Amplification and expansion of oncogenic pathways as metastatic traits (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Vanharanta S, Massagué J; ''Origins of metastatic traits.''; Cancer Cell, 2013 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	140880	view	00:51, 30 October 2025	Eweitz	Clear deprecated metadata rendering
	137096	view	22:44, 27 February 2025	Khanspers	Modified description
	128581	view	23:21, 14 February 2024	Eweitz	Economize layout
	117647	view	11:42, 22 May 2021	Eweitz	Modified title
	108162	view	10:45, 29 November 2019	Fehrhart	Ontology Term : 'cancer' added !
	105879	view	04:51, 16 August 2019	Khanspers	Modified description
	105526	view	05:59, 9 August 2019	Khanspers	Modified description
	90110	view	18:59, 13 October 2016	Khanspers	Modified description
	90109	view	18:59, 13 October 2016	Khanspers	Modified title
	90108	view	18:58, 13 October 2016	Khanspers	layout changes etc
	88755	view	18:45, 14 August 2016	AAR&Co	Ontology Term : 'von Hippel-Lindau disease' added !
	88754	view	18:43, 14 August 2016	AAR&Co	Ontology Term : 'cancer pathway' added !
	88547	view	01:32, 11 August 2016	AAR&Co	Modify Datanode
	88546	view	01:30, 11 August 2016	AAR&Co	Modify Datanodes
	88545	view	01:20, 11 August 2016	AAR&Co	Modified description
	88543	view	01:14, 11 August 2016	AAR&Co	Add citation
	88003	view	13:27, 25 July 2016	Elisa	Ontology Term : 'disease pathway' added !
	86272	view	12:49, 9 July 2016	AAR&Co	Change of Title
	86136	view	13:16, 1 July 2016	AAR&Co	Modified description
	86135	view	13:15, 1 July 2016	AAR&Co	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
AKT1	GeneProduct	ENSG00000142208 (Ensembl)
CXCL12	GeneProduct	ENSG00000107562 (Ensembl)
CXCR4	GeneProduct	ENSG00000121966 (Ensembl)
CYTIP	GeneProduct	ENSG00000115165 (Ensembl)
DNA demethylation	GeneProduct
HIF2A	GeneProduct	ENSG00000116016 (Ensembl)
Histone H3K27 demethylation
IGF1	GeneProduct	ENSG00000017427 (Ensembl)
IGF1rec	GeneProduct	ENSG00000140443 (Ensembl)
JAGGED	GeneProduct	ENSG00000101384 (Ensembl)
NOTCH	GeneProduct	ENSG00000148400 (Ensembl)
PI3K	GeneProduct	ENSG00000105851 (Ensembl)
Periostin	GeneProduct	ENSG00000133110 (Ensembl)
RTK	GeneProduct		receptor tyrosine kinase
SRC	GeneProduct	ENSG00000197122 (Ensembl)
TCF	GeneProduct
TNC	GeneProduct	ENSG00000041982 (Ensembl)
VCAM1	GeneProduct	ENSG00000162692 (Ensembl)
VEGFA	GeneProduct	ENSG00000112715 (Ensembl)
VHL	GeneProduct	ENSG00000134086 (Ensembl)
Wnt	GeneProduct

Annotated Interactions

No annotated interactions