Amplification and expansion of oncogenic pathways as metastatic traits (Homo sapiens)

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ChemotaxisstemnessCell survivalSurvivalBTumorigenesisAJAGGEDPeriostinCYTIPCXCR4DNA demethylationWntRTKVEGFACXCL12IGF1TCFVHLVCAM1NOTCHHIF2API3KIGF1recCXCR4TNCHistone H3K27 demethylationSRCAKT1PI3KAKT1Cell survival


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Bibliography

  1. Vanharanta S, Massagué J; ''Origins of metastatic traits.''; Cancer Cell, 2013 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
128581view23:21, 14 February 2024EweitzEconomize layout
117647view11:42, 22 May 2021EweitzModified title
108162view10:45, 29 November 2019FehrhartOntology Term : 'cancer' added !
105879view04:51, 16 August 2019KhanspersModified description
105526view05:59, 9 August 2019KhanspersModified description
90110view18:59, 13 October 2016KhanspersModified description
90109view18:59, 13 October 2016KhanspersModified title
90108view18:58, 13 October 2016Khansperslayout changes etc
88755view18:45, 14 August 2016AAR&CoOntology Term : 'von Hippel-Lindau disease' added !
88754view18:43, 14 August 2016AAR&CoOntology Term : 'cancer pathway' added !
88547view01:32, 11 August 2016AAR&CoModify Datanode
88546view01:30, 11 August 2016AAR&CoModify Datanodes
88545view01:20, 11 August 2016AAR&CoModified description
88543view01:14, 11 August 2016AAR&CoAdd citation
88003view13:27, 25 July 2016ElisaOntology Term : 'disease pathway' added !
86272view12:49, 9 July 2016AAR&CoChange of Title
86136view13:16, 1 July 2016AAR&CoModified description
86135view13:15, 1 July 2016AAR&CoNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProductENSG00000142208 (Ensembl)
CXCL12GeneProductENSG00000107562 (Ensembl)
CXCR4GeneProductENSG00000121966 (Ensembl)
CYTIPGeneProductENSG00000115165 (Ensembl)
DNA demethylationGeneProduct
HIF2AGeneProductENSG00000116016 (Ensembl)
Histone H3K27 demethylation
IGF1GeneProductENSG00000017427 (Ensembl)
IGF1rec GeneProductENSG00000140443 (Ensembl)
JAGGEDGeneProductENSG00000101384 (Ensembl)
NOTCHGeneProductENSG00000148400 (Ensembl)
PI3KGeneProductENSG00000105851 (Ensembl)
PeriostinGeneProductENSG00000133110 (Ensembl)
RTK GeneProductreceptor tyrosine kinase
SRCGeneProductENSG00000197122 (Ensembl)
TCFGeneProduct
TNCGeneProductENSG00000041982 (Ensembl)
VCAM1GeneProductENSG00000162692 (Ensembl)
VEGFAGeneProductENSG00000112715 (Ensembl)
VHLGeneProductENSG00000134086 (Ensembl)
WntGeneProduct

Annotated Interactions

No annotated interactions

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