Epigallocatechin-3-O-gallate / epigallocatechin / epicatechin breakdown pathway (Homo sapiens)

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5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone1-(3',4',5'-trihydroxyphenyl)-3-(2",4",6"-trihydroxy)propan-2-olMetabolite3',4'-dihydroxy-phenylacetic acidPyrocatechol1-(3',4'-dihydroxyphenyl)-3-(2",4",6"-trihydroxy)propan-2-ol(-)-Epigallocatechin-3-O-gallateMetabolite(-)-Epicatechin4'-hydroxy-phenylacetic acid(-)-EpigallocatechinMetaboliteHippuric acidPyrogallol5-(3',5'-dihydroxyphenyl)-gamma-valerolactone4-hydroxy-5(3',4'-didhydroxy-phenyl)-valeric acidMetabolite5-(3'-hydroxyphenyl)-gamma-valerolactone5-(4'-hydroxyphenyl)-gamma-valerolactoneGallic acid5-(3',4'-dihydroxyphenyl)-gamma-valerolactone1111111114-hydroxy-5-(3',5'-dihydroxyphenyl)-valeric acid11111114-hydroxy-5-(3',4',5'-trihydroxyphenyl)-valeric acid14-hydroxy-5-(3'-hydroxyphenyl)-valeric acid11


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Bibliography

  1. Roowi S, Stalmach A, Mullen W, Lean ME, Edwards CA, Crozier A; ''Green tea flavan-3-ols: colonic degradation and urinary excretion of catabolites by humans.''; J Agric Food Chem, 2010 PubMed Europe PMC Scholia
  2. van der Hooft JJJ, de Vos RC, Mihaleva V, Bino RJ, Ridder L, de Roo N, Jacobs DM, van Duynhoven JP, Vervoort J; ''Structural elucidation and quantification of phenolic conjugates present in human urine after tea intake.''; Analytical Chemistry, American Chemical Society, 2012 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
117712view12:27, 22 May 2021EweitzModified title
107147view14:23, 17 September 2019MaintBotChEBI identifier normalization
106198view12:09, 16 August 2019MaintBotHMDB identifier normalization
86207view10:41, 6 July 2016JjjvanderhooftChecked arrows - added lit ref to tea compounds (Roowi et al)
86203view07:10, 6 July 2016MaintBotAdded missing HMDB prefixes in the IDs.
86202view07:08, 6 July 2016MaintBotModified description
86193view17:55, 5 July 2016JjjvanderhooftModified description
86192view17:53, 5 July 2016MaintBotOntology Term : 'classic metabolic pathway' added !
86191view17:53, 5 July 2016MaintBotOntology Term : 'xenobiotic metabolic pathway' added !
86190view17:42, 5 July 2016JjjvanderhooftModified description
86189view15:18, 5 July 2016JjjvanderhooftModified title
86188view15:15, 5 July 2016JjjvanderhooftVersion 1 (copied from paper)
86187view15:14, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86186view15:03, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86185view14:52, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86184view14:42, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86183view14:28, 5 July 2016JjjvanderhooftSpecify description
86182view14:27, 5 July 2016JjjvanderhooftSpecify description
86181view14:20, 5 July 2016JjjvanderhooftSpecify description
86180view14:12, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86179view14:02, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86178view13:51, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86177view13:39, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86176view13:28, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86175view13:18, 5 July 2016JjjvanderhooftPeriodical save, work in progress
86174view13:07, 5 July 2016JjjvanderhooftNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(-)-EpicatechinMetabolite90 (ChEBI)
(-)-Epigallocatechin-3-O-gallateMetabolite4806 (ChEBI)
(-)-EpigallocatechinMetabolite42255 (ChEBI)
1-(3',4',5'-trihydroxyphenyl)- 3-(2",4",6"-trihydroxy)propan-2-olMetabolite
1-(3',4'-dihydroxyphenyl)- 3-(2",4",6"-trihydroxy)propan-2-olMetabolite
3',4'-dihydroxy- phenylacetic acidMetabolite
4'-hydroxy- phenylacetic acidMetabolite
4-hydroxy-5(3',4'-didhydroxy- phenyl)-valeric acidMetabolite41679 (HMDB)
4-hydroxy-5-(3',4',5'-trihydroxyphenyl)- valeric acidMetabolite
4-hydroxy-5-(3',5'-dihydroxyphenyl)- valeric acidMetabolite
4-hydroxy-5-(3'-hydroxyphenyl)- valeric acidMetabolite
5-(3',4',5'-trihydroxyphenyl) -gamma-valerolactoneMetabolite41691 (HMDB)
5-(3',4'-dihydroxyphenyl) -gamma-valerolactoneMetabolite89285 (ChEBI)
5-(3',5'-dihydroxyphenyl) -gamma-valerolactoneMetabolite29187 (HMDB)
5-(3'-hydroxyphenyl) -gamma-valerolactoneMetabolite
5-(4'-hydroxyphenyl) -gamma-valerolactoneMetabolite
Gallic acidMetabolite30778 (ChEBI)
Hippuric acidMetabolite18089 (ChEBI)
MetaboliteMetabolite
PyrocatecholMetabolite18135 (ChEBI)
PyrogallolMetabolite16164 (ChEBI)

Annotated Interactions

No annotated interactions

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