Blood clotting cascade (Bos taurus)

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1Extrinsic PathwayEnv/PrMFactor IXaThrombolysis+Factor XIaFibrin PolymerFactor XIIIaPlasmin+ Fibrin Split ProductsFactor VIIIaTissue InjuryFibrin MonomerTissue FactorIntrinsic PathwayFactor VIIa Factor XIIaEnvSERPINE1ZincVWFF10F8A1KLKB1F10SERPINF2F2Factor VaProthrombinase ComplexFGAF10F7F13BF12F9KLK1F5PLGF8PLATPLAUFibrinFGBFGGSERPINB2F11F2


Description

Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP272(71361) with a 81.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Luchtman-Jones L, Broze GJ Jr; ''The current status of coagulation.''; Ann Med, 1995 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
120913view06:17, 31 January 2022EgonwReplaced an old HMDB identifier with the current one
117481view10:59, 21 May 2021EweitzModified title
105964view11:49, 16 August 2019MaintBotHMDB identifier normalization
86998view14:40, 15 July 2016MkutmonOntology Term : 'coagulation cascade pathway' added !
80884view15:29, 30 June 2015MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
F10GeneProductENSBTAG00000016385 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2159
F11GeneProductENSBTAG00000003572 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2160
F12GeneProductENSBTAG00000018872 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2161
F13BGeneProductENSBTAG00000000070 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2165
F2GeneProductENSBTAG00000007148 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2147
F5GeneProduct
F7GeneProductENSBTAG00000007411 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2155
F8A1GeneProduct
F8GeneProductENSBTAG00000010726 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2157
F9GeneProductENSBTAG00000004003 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2158
FGAGeneProduct
FGBGeneProductENSBTAG00000022120 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2244
FGGGeneProductENSBTAG00000006745 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2266
Factor VaGeneProduct
FibrinMetabolite9001-31-4 (CAS)
KLK1GeneProductENSBTAG00000018539 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3816
KLKB1GeneProductENSBTAG00000009501 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3818
PLATGeneProductENSBTAG00000001244 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5327
PLAUGeneProductENSBTAG00000005947 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5328
PLGGeneProductENSBTAG00000001271 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5340
Prothrombinase ComplexGeneProduct
SERPINB2GeneProductENSBTAG00000023198 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5055
SERPINE1GeneProductENSBTAG00000014465 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054
SERPINF2GeneProductENSBTAG00000020859 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5345
VWFGeneProductENSBTAG00000012265 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7450
ZincMetaboliteHMDB01303 (HMDB)

Annotated Interactions

No annotated interactions
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