TLR4 signaling and tolerance (Homo sapiens)

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1, 2MyD88 DependentDNADNAMyD88 independentIL6IFNBIkkiIKKbNFKBTAB1MYD88IKKaTBK1RIP1TRAF3TIRAPIRAK-MIRF7MALNEMOIkBaTNFaTRAMTLR4MAP KinasesTAB2TAK1NAP1IRAK4TRIFTRAF6IRAK1IRF3SHIP1IRF3IRF7NFKB


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Fang Y, Hu J; ''Toll-like receptor and its roles in myocardial ischemic/reperfusion injury.''; Med Sci Monit, 2011 PubMed Europe PMC Scholia
  2. Marsh BJ, Stenzel-Poore MP; ''Toll-like receptors: novel pharmacological targets for the treatment of neurological diseases.''; Curr Opin Pharmacol, 2008 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
121712view04:53, 26 February 2022EweitzUse gene symbols
117847view15:16, 22 May 2021EweitzModified title
105835view23:09, 15 August 2019KhanspersModified description
90114view22:52, 13 October 2016Khanspersconnected line
90021view19:30, 8 October 2016AlexanderPicoModified description
89944view13:58, 6 October 2016EgonwModified description
89753view00:08, 30 September 2016KhanspersModified title
89736view23:31, 29 September 2016Khanspersrestored lost information
89735view23:23, 29 September 2016Khanspersconnected interactions
89640view22:51, 22 September 2016Khansperscleanup and added interaction coloring
88719view17:59, 12 August 2016AAR&CoAdded Data Node
88718view17:55, 12 August 2016AAR&CoOntology Term : 'neurological disorder disease pathway' added !
88717view17:54, 12 August 2016AAR&CoAdded New Data Nodes
88716view17:45, 12 August 2016AAR&CoPeriodical save, work in progress
88712view17:35, 12 August 2016AAR&CoPeriodical save, work in progress
88709view17:24, 12 August 2016AAR&CoPeriodical save, work in progress
88576view19:04, 11 August 2016Mkutmonfix unconnected lines
87411view11:29, 22 July 2016MkutmonOntology Term : 'regulatory pathway' added !
87285view17:14, 20 July 2016AAR&CoModified description
87210view14:15, 19 July 2016AAR&CoAdded details from another source and cited
87206view14:08, 19 July 2016AAR&CoPeriodical save, work in progress
87183view19:57, 18 July 2016AAR&CoNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
IFNBGeneProductENSG00000171855 (Ensembl)
IKKaGeneProduct62241001 (NCBI Protein)
IKKbGeneProduct1034660199 (NCBI Protein)
IL6GeneProductENSG00000136244 (Ensembl)
IRAK-MGeneProduct322510038 (NCBI Protein)
IRAK1GeneProductENSG00000184216 (Ensembl)
IRAK4GeneProductENSG00000198001 (Ensembl)
IRF3GeneProductENSG00000126456 (Ensembl)
IRF7GeneProductENSG00000185507 (Ensembl)
IkBaGeneProduct6706211 (NCBI Protein)
IkkiGeneProduct300937401 (NCBI Protein)
MALGeneProduct2654296 (NCBI Protein)
MAP KinasesGeneProductGeneral Term
MYD88GeneProductENSG00000172936 (Ensembl)
NAP1GeneProduct37359287 (NCBI Protein)
NEMOGeneProduct5031141 (NCBI Protein)
NFKBGeneProductENSG00000109320 (Ensembl) NFKB not specified
RIP1GeneProduct60393639 (NCBI Protein)
SHIP1GeneProduct64085167 (NCBI Protein)
TAB1GeneProductENSG00000100324 (Ensembl)
TAB2GeneProductENSG00000055208 (Ensembl)
TAK1GeneProduct1351190 (NCBI Protein)
TBK1GeneProductENSG00000183735 (Ensembl)
TIRAPGeneProductENSG00000150455 (Ensembl)
TLR4GeneProductENSG00000136869 (Ensembl)
TNFaGeneProduct37212 (NCBI Protein)
TRAF3GeneProductENSG00000131323 (Ensembl)
TRAF6GeneProductENSG00000175104 (Ensembl)
TRAMGeneProductENSG00000067167 (Ensembl) TRAM not specified
TRIFGeneProduct41281981 (NCBI Protein)

Annotated Interactions

No annotated interactions

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