TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) (Bos taurus)
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Pyruvate Dehydrogenase Complex
Pyruvate
Isocitrate
FH
CS
DLAT
Succinoyl-CoA
ACO1
Fumarate
2-Hydroxy-ethyl-
ThPP
Succinate
ACLY
SDHA
PDHA1
Phosphoenol-
pyruvate
OGDH
MDH1
OGDH
Glycolysis
(S)-Malate
DLD
SUCLG2
ThPP
Oxaloacetate
S-Succinyl-
dihydrolipoamide-E
Citrate
IDH1
Lipoamide-E
Dihydro-
lipoamide-E
Acetyl-CoA
PC
Oxalosuccinate
PCK1
DLST
IDH1
3-carboxy-1-
hydroxypropyl-ThPP
IDH3A
2-Oxo-glutarate
S-Acetyldihydro-
lipoamide-E
PDHA1
ThPP
Dihydro-
lipoamide-E
Lipoamide-E
DLD
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP2453(80143)
with a 100.0% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
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Compare
Revision
Action
Time
User
Comment
117622
view
11:43, 21 May 2021
Eweitz
Modified title
107061
view
14:14, 17 September 2019
MaintBot
ChEBI identifier normalization
87730
view
09:24, 25 July 2016
MirellaKalafati
Ontology Term : 'pyruvate dehydrogenase complex deficiency pathway' added !
87729
view
09:23, 25 July 2016
MirellaKalafati
Ontology Term : 'PW:0001752' removed !
87728
view
09:23, 25 July 2016
MirellaKalafati
Ontology Term : 'pyruvate dehydrogenase complex deficiency pathway' added !
87727
view
09:22, 25 July 2016
MirellaKalafati
Ontology Term : 'citric acid cycle pathway' added !
87726
view
09:21, 25 July 2016
MirellaKalafati
Ontology Term : 'disease pathway' added !
87725
view
09:21, 25 July 2016
MirellaKalafati
Modified title
87364
view
09:50, 22 July 2016
MaintBot
added missing graphids
80712
view
15:23, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
(S)-Malate
Metabolite
C00149 (KEGG Compound)
2-Hydroxy-ethyl- ThPP
Metabolite
C05125 (KEGG Compound)
2-Oxo-glutarate
Metabolite
C00026 (KEGG Compound)
3-carboxy-1- hydroxypropyl-ThPP
Metabolite
ACLY
GeneProduct
ENSBTAG00000016740 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000131473
ACO1
GeneProduct
ENSBTAG00000000555 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000122729
Acetyl-CoA
Metabolite
C00024 (KEGG Compound)
CS
GeneProduct
ENSBTAG00000004371 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000062485
Citrate
Metabolite
C00158 (KEGG Compound)
DLAT
GeneProduct
ENSBTAG00000038327 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000150768
DLD
GeneProduct
ENSBTAG00000001908 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091140
DLST
GeneProduct
ENSBTAG00000006463 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000119689
Dihydro- lipoamide-E
Metabolite
Dihydro- lipoamide-E
Metabolite
80219 (ChEBI)
FH
GeneProduct
ENSBTAG00000021688 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091483
Fumarate
Metabolite
C00122 (KEGG Compound)
Glycolysis
Pathway
WP534 (WikiPathways)
IDH1
GeneProduct
ENSBTAG00000020527 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138413
IDH3A
GeneProduct
ENSBTAG00000006227 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166411
Isocitrate
Metabolite
C00311 (KEGG Compound)
Lipoamide-E
Metabolite
C15972 (KEGG Compound)
MDH1
GeneProduct
ENSBTAG00000019295 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000014641
OGDH
GeneProduct
ENSBTAG00000006029 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105953
Oxaloacetate
Metabolite
C00036 (KEGG Compound)
Oxalosuccinate
Metabolite
C05379 (KEGG Compound)
PC
GeneProduct
ENSBTAG00000019700 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
PCK1
GeneProduct
ENSBTAG00000001936 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000124253
PDHA1
GeneProduct
ENSBTAG00000019852 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000131828
Phosphoenol- pyruvate
Metabolite
C00074 (KEGG Compound)
Pyruvate
Metabolite
C00022 (KEGG Compound)
S-Acetyldihydro- lipoamide-E
Metabolite
C16255 (KEGG Compound)
S-Succinyl- dihydrolipoamide-E
Metabolite
SDHA
GeneProduct
ENSBTAG00000046019 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000073578
SUCLG2
GeneProduct
ENSBTAG00000009541 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000172340
Succinate
Metabolite
C00042 (KEGG Compound)
Succinoyl-CoA
Metabolite
C00091 (KEGG Compound)
ThPP
Metabolite
C00068 (KEGG Compound)
Annotated Interactions
No annotated interactions
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