GPCRs, class A rhodopsin-like (Canis familiaris)

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ThrombinC5a anaphylatoxinEndothelinOlfactory OtherCannabisClass A Orphan/otherPlatelet ADP & KI01 receptorsChemokine receptor-likeORPHLGR like (hormone receptors)BONZO receptors (CXC6R)Platelet activating factorNeuropeptide YOlfactoryAdrenoceptorsAlpha AdrenoceptorsOpioidSomatostatinPurinoceptorsAmineAcetylcholine (muscarinic)Neuropeptide Y / peptide YYAPJ likeC-X-C ChemokinePurinoceptor type YChemokineC-C ChemokineInterleukin-8Rhodopsin OtherHormone proteinFollicle stimulating hormoneNucleotide-likeAdenosine(Rhod)opsinRhodopsin VertebrateVasopressin-likeSREBOther Chemokine ReceptorsFmet-leu-pheBombesinLutropin-choriogonadotropic hormoneOrexin & neuropeptide FFBeta AdrenoceptorsAdrenomedullin (G10D)Thyrotropin-releasing hormone and SecretagogueGP40 likeMas proto-oncogeneCCKMelatoninClass A OrphansNeuromedin UMelanocortinGPR45 likeDopamineHRH3GALR2OR2B6GPR15OR10A5CXCR7P2RY4OPN1SWNPY2RGPR75BRS3IL8RAOR2N1PLHCGRLOC491573ADRA1DLOC611352OR1A2CXCR5RRHGPR77HRH2GPR45CYSLTR1CHRM1TRHROR2H1CYSLTR2AVPR1AADRA2BCMKLR1P2RY1GRPRGPR20NPFFR1Q9UDD9OPN3CCRL2HTR2CGPR74PTAFREDNRAMTNR1BEDNRBP2RY10LOC491216OR2J1OR04A12LOC607285F2RL3CXCR3CCBP2NPBWR1GPR34GPR44HTR1FLOC484871OR3A1OR1C1ADRA1AGPR8CCR8OR7A5GPR63F2RL2GPR87CCR5GPR42FSHROPRK1GPR17OR1D2DRD3OR1Q1IL8RBLOC482725GPR173MCHR1MLNRCCR3ADRA2COR2J2OPRL1HTR7OPN1MWGPR25HTR4CNR1ADRB3OR2B3HTR6PRLHRP2RY5P2RY11OPN4GALR1CCR7HTR2BHTR1EGPR18OXTROR1A1CXCR4OR5V1OR2F2CCKBRCCR10BDKRB1OPN1LWOR2AG1OR1G1PTGER3MAS1NMUR2PTGDRCHRM4OR2F1FPR1ProstaglandinSSTR1CHRM3PTGER4OPRM1P2RY12OR1D4ADRA1BDRD4RHOPTGER1OR10H3GPR6OR3A4GPR68GPR31CCR9GPR32ADRB1MAS1LGPR39NPY5RNMBRGPR4GPR171HCRTR2GPR27GPR174P2RY14FFAR3ADORA2BCCR4OR7C1CX3CR1OR2S2RgrAGTR1GALR3GPR3FFAR2CCKARGPR12GPR37MC3RAGTR2SUCNR1HistamineTBXA2RHTR5ASSTR5DRD1FPRL2PTGFRFFAR1GPR83BradykininOR2D2GPR161GPR35SerotoninHCRTR1OR10A04OR2B2OPRD1ADORA1PPYR1LOC483541P2RY2C3AR1HRH1MC2RFPR2DRD2CCR2MTNR1ANPY1RNTSR2CNR2GPR50OR2W1DTMTGPR85ADORA3cOR2T23GHSRADORA2AOR10H2OR2A4F2RSSTR4NPY6RCCR6HTR1DSSTR3HTR1BPTGIROR10J1F2RL1LOC489317GPR21OR5I1CHRM2APLNRAVPR2GPR52OR7A10cOR2C1BDKRB2XCR1SSTR2LOC485348HTR1AMC4ROR11A1MC5RAVPR1BADRA2AOR2J3OR10H1LOC484873LPAR4ADRB2GPR109BOR3A3LPAR5GPERCCRL1GPR65GPR1DRD5cOR8D6PTGER2Angiotensin IIP2RY6OR12D3CCR1P2RY13GPR81GPR19OR1F1OR28A08HTR2ANMUR1CHRM5LTB4RMC1RNTSR1GPR22OR2H2


Description

No description

Comments

GenMAPP notes 
This MAPP was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP455(r21638) with a 68% conversion rate.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117453view10:54, 21 May 2021EweitzModified title
106060view11:57, 16 August 2019MaintBotHMDB identifier normalization
87582view02:25, 25 July 2016AlexanderPicoOntology Term : 'signaling pathway' added !
71471view19:17, 17 October 2013MaintBotAutomated update of data sources
68555view22:40, 5 July 2013MaintBotUpdated to 2013 gpml schema
62720view03:17, 2 May 2013MaintBotUpdated UniProt data source
40711view21:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
33990view18:35, 9 December 2009MaintBotAutomatic update of empty xrefs
32267view13:03, 15 August 2009MaintBotFixed text labels
31798view12:18, 14 August 2009MaintBotFixed group labels
31295view20:08, 13 August 2009MaintBotFixed text labels
30757view23:10, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADORA1GeneProduct403961 (Entrez Gene)
ADORA2AGeneProduct403960 (Entrez Gene)
ADORA2BGeneProduct403410 (Entrez Gene)
ADORA3GeneProduct403805 (Entrez Gene)
ADRA1AGeneProduct403866 (Entrez Gene)
ADRA1BGeneProduct403962 (Entrez Gene)
ADRA1DGeneProduct552897 (Entrez Gene)
ADRA2AGeneProduct486888 (Entrez Gene)
ADRA2BGeneProduct611658 (Entrez Gene)
ADRA2CGeneProduct488793 (Entrez Gene)
ADRB1GeneProduct493972 (Entrez Gene)
ADRB2GeneProduct403910 (Entrez Gene)
ADRB3GeneProduct442979 (Entrez Gene)
AGTR1GeneProduct403836 (Entrez Gene)
AGTR2GeneProduct403835 (Entrez Gene)
APLNRGeneProduct483497 (Entrez Gene)
AVPR1AGeneProduct481142 (Entrez Gene)
AVPR1BGeneProduct488578 (Entrez Gene)
AVPR2GeneProduct403804 (Entrez Gene)
Angiotensin IIMetaboliteHMDB01035 (HMDB)
BDKRB1GeneProduct490847 (Entrez Gene)
BDKRB2GeneProduct403658 (Entrez Gene)
BRS3GeneProduct613002 (Entrez Gene)
BradykininMetabolite
C3AR1GeneProduct486704 (Entrez Gene)
CCBP2GeneProduct485618 (Entrez Gene)
CCKARGeneProduct488846 (Entrez Gene)
CCKBRGeneProduct485333 (Entrez Gene)
CCR10GeneProduct607528 (Entrez Gene)
CCR1GeneProduct484791 (Entrez Gene)
CCR2GeneProduct484790 (Entrez Gene)
CCR3GeneProduct448802 (Entrez Gene)
CCR4GeneProduct403541 (Entrez Gene)
CCR5GeneProduct484789 (Entrez Gene)
CCR6GeneProduct484080 (Entrez Gene)
CCR7GeneProduct491011 (Entrez Gene)
CCR8GeneProduct485600 (Entrez Gene)
CCR9GeneProduct484793 (Entrez Gene)
CCRL1GeneProduct608898 (Entrez Gene)
CCRL2GeneProduct484788 (Entrez Gene)
CHRM1GeneProduct483776 (Entrez Gene)
CHRM2GeneProduct403858 (Entrez Gene)
CHRM3GeneProduct403827 (Entrez Gene)
CHRM4GeneProduct611314 (Entrez Gene)
CHRM5GeneProduct487472 (Entrez Gene)
CMKLR1GeneProduct486321 (Entrez Gene)
CNR1GeneProduct481913 (Entrez Gene)
CNR2GeneProduct612289 (Entrez Gene)
CX3CR1GeneProduct485599 (Entrez Gene)
CXCR3GeneProduct491952 (Entrez Gene)
CXCR4GeneProduct483900 (Entrez Gene)
CXCR5GeneProduct489378 (Entrez Gene)
CXCR7GeneProduct403964 (Entrez Gene)
CYSLTR1GeneProduct608345 (Entrez Gene)
CYSLTR2GeneProduct485445 (Entrez Gene)
DRD1GeneProduct489110 (Entrez Gene)
DRD2GeneProduct403701 (Entrez Gene)
DRD3GeneProduct487984 (Entrez Gene)
DRD4GeneProduct448805 (Entrez Gene)
DRD5GeneProduct488824 (Entrez Gene)
DTMTGeneProduct491217 (Entrez Gene)
DopamineMetabolite
EDNRAGeneProduct450187 (Entrez Gene)
EDNRBGeneProduct403862 (Entrez Gene)
F2RGeneProduct488942 (Entrez Gene)
F2RL1GeneProduct488940 (Entrez Gene)
F2RL2GeneProduct607963 (Entrez Gene)
F2RL3GeneProduct484846 (Entrez Gene)
FFAR1GeneProduct612661 (Entrez Gene)
FFAR2GeneProduct484580 (Entrez Gene)
FFAR3GeneProduct612659 (Entrez Gene)
FPR1GeneProduct
FPR2GeneProduct611696 (Entrez Gene)
FPRL2GeneProduct
FSHRGeneProduct481367 (Entrez Gene)
GALR1GeneProduct483928 (Entrez Gene)
GALR2GeneProduct483325 (Entrez Gene)
GALR3GeneProduct610233 (Entrez Gene)
GHSRGeneProduct100101479 (Entrez Gene)
GPERGeneProduct480808 (Entrez Gene)
GPR109BGeneProduct
GPR12GeneProduct486034 (Entrez Gene)
GPR1GeneProduct478882 (Entrez Gene)
GPR15GeneProduct487947 (Entrez Gene)
GPR161GeneProduct490358 (Entrez Gene)
GPR17GeneProduct
GPR171GeneProduct485716 (Entrez Gene)
GPR173GeneProduct491892 (Entrez Gene)
GPR174GeneProduct
GPR18GeneProduct485531 (Entrez Gene)
GPR19GeneProduct
GPR20GeneProduct482061 (Entrez Gene)
GPR21GeneProduct612859 (Entrez Gene)
GPR22GeneProduct607459 (Entrez Gene)
GPR25GeneProduct
GPR27GeneProduct
GPR31GeneProduct484081 (Entrez Gene)
GPR32GeneProduct
GPR34GeneProduct
GPR3GeneProduct487344 (Entrez Gene)
GPR35GeneProduct486201 (Entrez Gene)
GPR37GeneProduct482275 (Entrez Gene)
GPR39GeneProduct610696 (Entrez Gene)
GPR42GeneProduct
GPR44GeneProduct483805 (Entrez Gene)
GPR4GeneProduct484440 (Entrez Gene)
GPR45GeneProduct481321 (Entrez Gene)
GPR50GeneProduct492213 (Entrez Gene)
GPR52GeneProduct
GPR63GeneProduct
GPR6GeneProduct481959 (Entrez Gene)
GPR65GeneProduct490821 (Entrez Gene)
GPR68GeneProduct
GPR74GeneProduct
GPR75GeneProduct
GPR77GeneProduct612145 (Entrez Gene)
GPR8GeneProduct
GPR81GeneProduct486252 (Entrez Gene)
GPR83GeneProduct403699 (Entrez Gene)
GPR85GeneProduct482410 (Entrez Gene)
GPR87GeneProduct485718 (Entrez Gene)
GRPRGeneProduct491754 (Entrez Gene)
HCRTR1GeneProduct487320 (Entrez Gene)
HCRTR2GeneProduct399545 (Entrez Gene)
HRH1GeneProduct403813 (Entrez Gene)
HRH2GeneProduct403812 (Entrez Gene)
HRH3GeneProduct477282 (Entrez Gene)
HTR1AGeneProduct487230 (Entrez Gene)
HTR1BGeneProduct403741 (Entrez Gene)
HTR1DGeneProduct403963 (Entrez Gene)
HTR1EGeneProduct481907 (Entrez Gene)
HTR1FGeneProduct
HTR2AGeneProduct403882 (Entrez Gene)
HTR2BGeneProduct403881 (Entrez Gene)
HTR2CGeneProduct450240 (Entrez Gene)
HTR4GeneProduct489198 (Entrez Gene)
HTR5AGeneProduct482814 (Entrez Gene)
HTR6GeneProduct487402 (Entrez Gene)
HTR7GeneProduct477762 (Entrez Gene)
HistamineMetabolite
IL8RAGeneProduct
IL8RBGeneProduct478906 (Entrez Gene)
LHCGRGeneProduct481365 (Entrez Gene)
LOC482725GeneProduct482725 (Entrez Gene)
LOC483541GeneProduct483541 (Entrez Gene)
LOC484871GeneProduct484871 (Entrez Gene)
LOC484873GeneProduct484873 (Entrez Gene)
LOC485348GeneProduct485348 (Entrez Gene)
LOC489317GeneProduct489317 (Entrez Gene)
LOC491216GeneProduct491216 (Entrez Gene)
LOC491573GeneProduct491573 (Entrez Gene)
LOC607285GeneProduct607285 (Entrez Gene)
LOC611352GeneProduct611352 (Entrez Gene)
LPAR4GeneProduct491978 (Entrez Gene)
LPAR5GeneProduct486724 (Entrez Gene)
LTB4RGeneProduct608461 (Entrez Gene)
MAS1GeneProduct484066 (Entrez Gene)
MAS1LGeneProduct
MC1RGeneProduct489652 (Entrez Gene)
MC2RGeneProduct483980 (Entrez Gene)
MC3RGeneProduct485938 (Entrez Gene)
MC4RGeneProduct483961 (Entrez Gene)
MC5RGeneProduct483981 (Entrez Gene)
MCHR1GeneProduct403563 (Entrez Gene)
MLNRGeneProduct608252 (Entrez Gene)
MTNR1AGeneProduct482904 (Entrez Gene)
MTNR1BGeneProduct607818 (Entrez Gene)
NMBRGeneProduct611644 (Entrez Gene)
NMUR1GeneProduct
NMUR2GeneProduct489170 (Entrez Gene)
NPBWR1GeneProduct486949 (Entrez Gene)
NPFFR1GeneProduct609566 (Entrez Gene)
NPY1RGeneProduct399518 (Entrez Gene)
NPY2RGeneProduct482661 (Entrez Gene)
NPY5RGeneProduct403712 (Entrez Gene)
NPY6RGeneProduct
NTSR1GeneProduct485963 (Entrez Gene)
NTSR2GeneProduct482972 (Entrez Gene)
OPN1LWGeneProduct403778 (Entrez Gene)
OPN1MWGeneProduct
OPN1SWGeneProduct482267 (Entrez Gene)
OPN3GeneProduct611646 (Entrez Gene)
OPN4GeneProduct611027 (Entrez Gene)
OPRD1GeneProduct487329 (Entrez Gene)
OPRK1GeneProduct486951 (Entrez Gene)
OPRL1GeneProduct485985 (Entrez Gene)
OPRM1GeneProduct484041 (Entrez Gene)
OR04A12GeneProduct484985 (Entrez Gene)
OR10A04GeneProduct491211 (Entrez Gene)
OR10A5GeneProduct
OR10H1GeneProduct
OR10H2GeneProduct
OR10H3GeneProduct
OR10J1GeneProduct
OR11A1GeneProduct
OR12D3GeneProduct
OR1A1GeneProduct
OR1A2GeneProduct
OR1C1GeneProduct
OR1D2GeneProduct
OR1D4GeneProduct
OR1F1GeneProduct
OR1G1GeneProduct
OR1Q1GeneProduct
OR28A08GeneProduct485351 (Entrez Gene)
OR2A4GeneProduct
OR2AG1GeneProduct
OR2B2GeneProduct
OR2B3GeneProduct
OR2B6GeneProduct
OR2D2GeneProduct
OR2F1GeneProduct
OR2F2GeneProduct
OR2H1GeneProduct
OR2H2GeneProduct
OR2J1GeneProduct
OR2J2GeneProduct
OR2J3GeneProduct
OR2N1PGeneProduct
OR2S2GeneProduct
OR2W1GeneProduct
OR3A1GeneProduct
OR3A3GeneProduct
OR3A4GeneProduct
OR5I1GeneProduct
OR5V1GeneProduct
OR7A10GeneProduct
OR7A5GeneProduct
OR7C1GeneProduct
OXTRGeneProduct484670 (Entrez Gene)
P2RY10GeneProduct491980 (Entrez Gene)
P2RY11GeneProduct
P2RY12GeneProduct442958 (Entrez Gene)
P2RY13GeneProduct609841 (Entrez Gene)
P2RY14GeneProduct485717 (Entrez Gene)
P2RY1GeneProduct449621 (Entrez Gene)
P2RY2GeneProduct485203 (Entrez Gene)
P2RY4GeneProduct
P2RY5GeneProduct
P2RY6GeneProduct485202 (Entrez Gene)
PPYR1GeneProduct489082 (Entrez Gene)
PRLHRGeneProduct486911 (Entrez Gene)
PTAFRGeneProduct487336 (Entrez Gene)
PTGDRGeneProduct610845 (Entrez Gene)
PTGER1GeneProduct610774 (Entrez Gene)
PTGER2GeneProduct403797 (Entrez Gene)
PTGER3GeneProduct403430 (Entrez Gene)
PTGER4GeneProduct403589 (Entrez Gene)
PTGFRGeneProduct479981 (Entrez Gene)
PTGIRGeneProduct484429 (Entrez Gene)
ProstaglandinMetabolite
Q9UDD9GeneProduct
RHOGeneProduct493763 (Entrez Gene)
RRHGeneProduct610525 (Entrez Gene)
RgrGeneProduct489072 (Entrez Gene)
SSTR1GeneProduct403455 (Entrez Gene)
SSTR2GeneProduct403472 (Entrez Gene)
SSTR3GeneProduct481272 (Entrez Gene)
SSTR4GeneProduct
SSTR5GeneProduct403454 (Entrez Gene)
SUCNR1GeneProduct485719 (Entrez Gene)
SerotoninMetabolite
TBXA2RGeneProduct485056 (Entrez Gene)
TRHRGeneProduct482007 (Entrez Gene)
XCR1GeneProduct484792 (Entrez Gene)
cOR2C1GeneProduct490037 (Entrez Gene)
cOR2T23GeneProduct482238 (Entrez Gene)
cOR8D6GeneProduct489330 (Entrez Gene)

Annotated Interactions

No annotated interactions
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