Superpathway of pyridoxal 5'-phosphate biosynthesis and salvage (Solanum lycopersicum)

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3, 9-11, 18D-erythrose-4-phosphate 1.2.1.72 32erythronate-4-phosphate 2-oxo-3-hydroxy-4-phosphobutanoate 4-(phosphonooxy)-threonine (2S)-2-amino-3-oxo-4-phosphonooxybutanoate3-amino-1-hydroxyacetone 1-phosphateD-glyceraldehyde-3-phosphate 6, 8, 22, 271-deoxy-D-xylulose 5-phosphate 16pyridoxine-5'-phosphate pyridoxal 5'-phosphate 23, 261, 2, 4, 5, 7...pyridoxal 26, 29pyridoxine pyridoxamine 31pyridoxamine 5'-phosphate 262.6.1.52 26, 301.1.1.2622.2.1.7 1.1.1.290 2.6.99.2 2.7.1.- 2.7.1.35 1.4.3.5 1.4.3.5 2.7.1.35


Description

Pyridoxal 5'-phosphate (PLP) is the biochemically active form of pyridoxine 5'-phosphate (PNP)or vitamin B6. PLP is an essential cofactor of numerous metabolic enzymes, predominantly in amino acid metabolism

Comments

 
Synonyms: vitamin B6 biosynthesis and salvage / This superpathway shows the various ways that E. coli can obtain pyridoxal 5'-phosphate, a coenzyme for many enzymes that participate in amino acid and glycogen metabolism.
 
This pathway has been manually created based on Lycocyc content: Lyco: PWY0-845

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Ontology Terms

 

Bibliography

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  24. Miller AD, Packman LC, Hart GJ, Alefounder PR, Abell C, Battersby AR; ''Evidence that pyridoxal phosphate modification of lysine residues (Lys-55 and Lys-59) causes inactivation of hydroxymethylbilane synthase (porphobilinogen deaminase).''; Biochem J, 1989 PubMed Europe PMC Scholia
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History

View all...
CompareRevisionActionTimeUserComment
107271view14:36, 17 September 2019MaintBotChEBI identifier normalization
87608view08:54, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
73656view17:41, 12 February 2014AndraChanged the layout to reflect the source
73655view16:41, 12 February 2014AndraAdded literature
73653view11:46, 12 February 2014AndraModified description
73652view11:41, 12 February 2014Andra
73648view23:48, 11 February 2014LarsEijssenNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
(2S)-2-amino-3-oxo-4-phosphonooxybutanoateMetabolite441260 (PubChem-compound)
1-deoxy-D-xylulose 5-phosphate Metabolite16493 (ChEBI)
1.1.1.262GeneProduct1.1.1.262 (Enzyme Nomenclature)
1.1.1.290 GeneProduct1.1.1.290 (Enzyme Nomenclature)
1.2.1.72 GeneProduct1.2.1.72 (Enzyme Nomenclature)
1.4.3.5 GeneProduct1.4.3.5 (Enzyme Nomenclature)
2-oxo-3-hydroxy-4-phosphobutanoate Metabolite27951 (ChEBI)
2.2.1.7 GeneProduct2.2.1.7 (Enzyme Nomenclature)
2.6.1.52 GeneProduct2.6.1.52 (Enzyme Nomenclature)
2.6.99.2 GeneProduct2.6.99.2 (Enzyme Nomenclature)
2.7.1.- GeneProduct2.7.1.- (Enzyme Nomenclature)
2.7.1.35 GeneProduct2.7.1.35 (Enzyme Nomenclature)
3-amino-1-hydroxyacetone 1-phosphateMetabolite1449 (ChEBI)
4-(phosphonooxy)-threonine Metabolite18336 (ChEBI)
D-erythrose-4-phosphate Metabolite48153 (ChEBI)
D-glyceraldehyde-3-phosphate Metabolite17138 (ChEBI)
erythronate-4-phosphate Metabolite49003 (ChEBI)
pyridoxal Metabolite17310 (ChEBI)
pyridoxal 5'-phosphate Metabolite18405 (ChEBI)
pyridoxamine Metabolite16410 (ChEBI)
pyridoxamine 5'-phosphate Metabolite18335 (ChEBI)
pyridoxine Metabolite16709 (ChEBI)
pyridoxine-5'-phosphate Metabolite28803 (ChEBI)

Annotated Interactions

No annotated interactions
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