Novel intracellular components of RIG-I-like receptor pathway (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. van der Lee R, Feng Q, Langereis MA, Ter Horst R, Szklarczyk R, Netea MG, Andeweg AC, van Kuppeveld FJ, Huynen MA; ''Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response.''; PLoS Comput Biol, 2015 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	123636	view	09:43, 7 August 2022	Egonw	Modified title
	123123	view	18:07, 4 July 2022	Egonw	Made four pathways clickable
	106524	view	23:45, 5 September 2019	Khanspers	Modified description
	105798	view	22:48, 15 August 2019	Khanspers	Modified description
	104869	view	19:51, 21 June 2019	AlexanderPico	Modified description
	104868	view	19:48, 21 June 2019	AlexanderPico	Modified title
	104581	view	12:47, 2 June 2019	Yt	Modified title
	88186	view	00:44, 30 July 2016	AlexanderPico	Added newly discovered viral RNA-host RLR components
	88185	view	00:39, 30 July 2016	AlexanderPico	Ontology Term : 'viral infectious disease' added !
	88184	view	00:38, 30 July 2016	AlexanderPico	Ontology Term : 'signaling pathway in the innate immune response' added !
	88183	view	00:38, 30 July 2016	AlexanderPico	Ontology Term : 'signaling pathway' added !
	88182	view	00:38, 30 July 2016	AlexanderPico	Modified description
	88181	view	00:23, 30 July 2016	AlexanderPico	Added literature reference
	88180	view	00:22, 30 July 2016	AlexanderPico	fixed complex position
	88179	view	00:21, 30 July 2016	AlexanderPico	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
5'ppp-RNA	Rna
ATG12	GeneProduct	ENSG00000145782 (Ensembl)
ATG5	GeneProduct	ENSG00000057663 (Ensembl)
AZI2	GeneProduct	ENSG00000163512 (Ensembl)
Apoptosis	Pathway	WP254 (WikiPathways)
CASP10	GeneProduct	ENSG00000003400 (Ensembl)
CASP8	GeneProduct	ENSG00000064012 (Ensembl)
CHUK	GeneProduct	ENSG00000213341 (Ensembl)
CXCL10	GeneProduct	ENSG00000169245 (Ensembl)
CXCL12	GeneProduct	ENSG00000107562 (Ensembl)
CXCL8	GeneProduct	ENSG00000169429 (Ensembl)
CYLD	GeneProduct	ENSG00000083799 (Ensembl)
DAK	GeneProduct	ENSG00000149476 (Ensembl)
DDX17	GeneProduct	ENSG00000100201 (Ensembl)
DDX3X	GeneProduct	ENSG00000215301 (Ensembl)
DDX3Y	GeneProduct	ENSG00000067048 (Ensembl)
DDX58	GeneProduct	ENSG00000107201 (Ensembl)
DHX58	GeneProduct	ENSG00000108771 (Ensembl)
FADD	GeneProduct	ENSG00000168040 (Ensembl)
IFIH1	GeneProduct	ENSG00000115267 (Ensembl)
IFNA1	GeneProduct	ENSG00000197919 (Ensembl)
IFNB1	GeneProduct	ENSG00000171855 (Ensembl)
IFNE	GeneProduct	ENSG00000184995 (Ensembl)
IFNG	GeneProduct	ENSG00000111537 (Ensembl)
IFNK	GeneProduct	ENSG00000147896 (Ensembl)
IKBKB	GeneProduct	ENSG00000104365 (Ensembl)
IKBKE	GeneProduct	ENSG00000263528 (Ensembl)
IKBKG	GeneProduct	ENSG00000269335 (Ensembl)
IRF3	GeneProduct	ENSG00000126456 (Ensembl)
IRF7	GeneProduct	ENSG00000185507 (Ensembl)
ISG15	GeneProduct	ENSG00000187608 (Ensembl)
MAP3K1	GeneProduct	ENSG00000095015 (Ensembl)
MAP3K7	GeneProduct	ENSG00000135341 (Ensembl)
MAPK signaling	Pathway	WP382 (WikiPathways)
MAPK10	GeneProduct	ENSG00000109339 (Ensembl)
MAPK11	GeneProduct	ENSG00000185386 (Ensembl)
MAPK12	GeneProduct	ENSG00000188130 (Ensembl)
MAPK13	GeneProduct	ENSG00000156711 (Ensembl)
MAPK14	GeneProduct	ENSG00000112062 (Ensembl)
MAPK8	GeneProduct	ENSG00000107643 (Ensembl)
MAPK9	GeneProduct	ENSG00000050748 (Ensembl)
MAVS	GeneProduct	ENSG00000088888 (Ensembl)
NFKB1	GeneProduct	ENSG00000109320 (Ensembl)
NFKBIA	GeneProduct	ENSG00000100906 (Ensembl)
NFKBIB	GeneProduct	ENSG00000104825 (Ensembl)
NLRX1	GeneProduct	ENSG00000160703 (Ensembl)
OTUD5	GeneProduct	ENSG00000068308 (Ensembl)
PIN1	GeneProduct	ENSG00000127445 (Ensembl)
RELA	GeneProduct	ENSG00000173039 (Ensembl)
RIPK1	GeneProduct	ENSG00000137275 (Ensembl)
RNF125	GeneProduct	ENSG00000101695 (Ensembl)
SIKE1	GeneProduct	ENSG00000052723 (Ensembl)
SNW1	GeneProduct	ENSG00000100603 (Ensembl)
TANK	GeneProduct	ENSG00000136560 (Ensembl)
TBK1	GeneProduct	ENSG00000183735 (Ensembl)
TBKBP1	GeneProduct	ENSG00000198933 (Ensembl)
TMEM173	GeneProduct	ENSG00000184584 (Ensembl)
TNFA	Protein	ENSG00000232810 (Ensembl)
TRADD	GeneProduct	ENSG00000102871 (Ensembl)
TRAF2	GeneProduct	ENSG00000127191 (Ensembl)
TRAF3	GeneProduct	ENSG00000131323 (Ensembl)
TRAF6	GeneProduct	ENSG00000175104 (Ensembl)
TRIM25	GeneProduct	ENSG00000121060 (Ensembl)
Ub-mediated proteolysis	Pathway	WP183 (WikiPathways)
long dsRNA	Rna
short dsRNA	Rna

Annotated Interactions

No annotated interactions