Hypoxia-mediated EMT and stemness (Homo sapiens)

Revision as of 15:19, 12 August 2016 by Jmelius (Talk | contribs)

Description

Model of hypoxia mediated EMT and stemness.

View approved pathways at the new wikipathways.org.

Review changes for Approved

Pathway Ontology : disease pathway

Disease : heart disease

Cell Type : muscle cell cell of skeletal muscle

van den Beucken T, Koch E, Chu K, Rupaimoole R, Prickaerts P, Adriaens M, Voncken JW, Harris AL, Buffa FM, Haider S, Starmans MH, Yao CQ, Ivan M, Ivan C, Pecot CV, Boutros PC, Sood AK, Koritzinsky M, Wouters BG; ''Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.''; Nat Commun, 2014 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
128729 Approved	view	02:51, 21 February 2024	Eweitz	Upgrade disease node, economize layout, standardize case
117758	view	12:53, 22 May 2021	Eweitz	Modified title
88661	view	15:19, 12 August 2016	Jmelius	Ontology Term : 'regulatory pathway' added !
83778	view	15:12, 4 December 2015	Susan	Add IDs miRNAs and changed miRNA names
81089	view	21:17, 21 July 2015	Khanspers
80336	view	22:30, 5 June 2015	Khanspers	Modified description
80335	view	22:28, 5 June 2015	Khanspers	New pathway

Name	Type	Database reference
DICER1	GeneProduct	23405 (Entrez Gene)
ZEB1	GeneProduct	6935 (Entrez Gene)
hsa-miR-200a-3p	Rna	MIMAT0000682 (miRBase mature sequence)
hsa-miR-200b-3p	Rna	MIMAT0000318 (miRBase mature sequence)
hsa-miR-200c-3p	Rna	MIMAT0000617 (miRBase mature sequence)

No annotated interactions