Complement and Coagulation Cascades (Gallus gallus)

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C3aPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation, etcZymosan,insulin, etc.Alternative PathwayCollagen,basement membrane,activated platelets, etc.Cell adhesion,migration,profileration, etcComplement CascadeC3ConvertaseC3bC3b/BbCross-linkedfibrin polymerMediatorsC4aCell lysisClotClassical PathwayDegredationAntibody/antigencomplexThrombinMuscle contraction,Chemotaxis,Phagocyte recruitmentInflammation, etc.Cell adhesion,migration,profileration, etcCoagulation CascadeFibrinolytic systemLectin PathwayVascular injurymembrane attack complexC5aC3b/4b, C3b, C3dExtrinsic pathwayC4b/2afibrin degredationproductsKinin kallikrein systemF2RC2C1QCTFPIF12Daf1VWFKNG1CRRYCR2C1SPLGC4F7F9KLKB1C6C8GF5CR1MBL1SERPINC1C1QBSERPINA5F10Daf2THBDHcPLAU109821PLAURPROS1MASP1CPB2BDKRB1FGBA2MC3CFHCFIADNFibrin monomerC1RH2-BFSERPIND1C1QAC9MASP2PLATC5AR1F2F3SERPINF2SERPING1C7PROCSERPINA1F13BC4BPBradykininMCPF8SERPINE1C3AR1CD59A


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP558(r22582) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
122619view08:30, 22 April 2022DdiglesReverted to version '03:59, 23 August 2016' by Ddigles
122584view10:00, 18 April 2022EweitzModified title
89198view03:59, 23 August 2016AriuttaOntology Term : 'hemostasis pathway' added !
89197view03:59, 23 August 2016AriuttaOntology Term : 'coagulation cascade pathway' added !
89196view03:59, 23 August 2016AriuttaOntology Term : 'complement system pathway' added !
74335view13:15, 13 April 2014EgonwAdded a missing metabolite identifier.
68852view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
40990view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
38705view19:28, 23 September 2010AlexanderPico
33912view18:04, 9 December 2009MaintBotAutomatic update of empty xrefs
33491view15:11, 30 November 2009MaintBotRemoved group label
31540view21:48, 13 August 2009MaintBotFixed text labels
30389view21:05, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2MGeneProduct418251 (Entrez Gene)
ADNGeneProduct
BDKRB1GeneProduct772372 (Entrez Gene)
BradykininMetaboliteCHEBI:3165 (ChEBI)
C1QAGeneProduct419504 (Entrez Gene)
C1QBGeneProduct428197 (Entrez Gene)
C1QCGeneProduct419503 (Entrez Gene)
C1RGeneProduct418295 (Entrez Gene)
C1SGeneProduct418294 (Entrez Gene)
C2GeneProduct419574 (Entrez Gene)
C3GeneProduct396370 (Entrez Gene)
C3AR1GeneProduct418198 (Entrez Gene)
C4GeneProduct426611 (Entrez Gene)
C4BPGeneProduct
C5AR1GeneProduct430484 (Entrez Gene)
C6GeneProduct431585 (Entrez Gene)
C7GeneProduct427187 (Entrez Gene) MGI:88235 LL:109828
C8GGeneProduct770691 (Entrez Gene)
C9GeneProduct
CD59AGeneProduct
CFHGeneProduct429057 (Entrez Gene)
CFIGeneProduct428773 (Entrez Gene)
CPB2GeneProduct418851 (Entrez Gene)
CR1GeneProduct
CR2GeneProduct
CRRYGeneProduct
Daf1GeneProduct
Daf2GeneProduct
F10GeneProduct395876 (Entrez Gene)
F12GeneProduct
F13BGeneProduct424355 (Entrez Gene)
F2GeneProduct395306 (Entrez Gene)
F2RGeneProduct427212 (Entrez Gene)
F3GeneProduct429084 (Entrez Gene)
F5GeneProduct374052 (Entrez Gene)
F7GeneProduct395086 (Entrez Gene)
F8GeneProduct422199 (Entrez Gene)
F9GeneProduct374258 (Entrez Gene)
FGBGeneProduct373926 (Entrez Gene)
Fibrin monomerMetabolite
H2-BFGeneProduct
HcGeneProduct
KLKB1GeneProduct
KNG1GeneProduct424957 (Entrez Gene)
MASP1GeneProduct407088 (Entrez Gene)
MASP2GeneProduct407089 (Entrez Gene)
MBL1GeneProduct
MCPGeneProduct
PLATGeneProduct426791 (Entrez Gene)
PLAUGeneProduct396424 (Entrez Gene)
PLAURGeneProduct
PLGGeneProduct421580 (Entrez Gene)
PROCGeneProduct395085 (Entrez Gene)
PROS1GeneProduct418430 (Entrez Gene)
SERPINA1GeneProduct423434 (Entrez Gene)
SERPINA5GeneProduct423435 (Entrez Gene)
SERPINC1GeneProduct424440 (Entrez Gene)
SERPIND1GeneProduct395877 (Entrez Gene)
SERPINE1GeneProduct
SERPINF2GeneProduct417561 (Entrez Gene)
SERPING1GeneProduct423132 (Entrez Gene)
TFPIGeneProduct423989 (Entrez Gene)
THBDGeneProduct428546 (Entrez Gene)
VWFGeneProduct419031 (Entrez Gene)
109821GeneProduct

Annotated Interactions

No annotated interactions
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