Biogenic amine synthesis (Drosophila melanogaster)

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15-hydroxy-tryptophanPhenylalaninefollow solid arrows through enzymatic steps,GABAAcetylserotoninwhile degradation steps follow dashed arrows.TryptophanL-DOPAAcetylcholineDopamineCholineTyrosineEpinephrineGlutamateHistamineSynthesis pathways for biogenic amines (in blue)HistidineMelatoninNorepinephrineSerotoninDdcDdcMAOAGAD2ChaGad1TrhACHEHnAANATDdcTbhpleASMTPNMTHdcCOMTMAOA


Description

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

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Quality Tags

Ontology Terms

 

Bibliography

  1. Purves, Dale, Augustine, George J., Fitzpatrick, David, Katz, Lawrence C., LaMantia, Anthony-Samuel, McNamara, James O., Williams, S. Mark.; ''Neuroscience''; ISBN 0878937420, 2001

History

View all...
CompareRevisionActionTimeUserComment
135412view19:24, 3 September 2024Khanspersminor layout change to trigger update
135339view18:52, 26 August 2024Khanspersswitch ref to ISBN
135335view20:42, 23 August 2024Khanspersupdated lit ref
120778view22:11, 4 January 2022Khanspersadded missing xref
120777view22:07, 4 January 2022Khanspersconnected enzymes, added xrefs for metabolites
116914view11:56, 15 May 2021EweitzModified title
102068view00:25, 28 November 2018Elisson nlGene id added
92244view23:39, 15 May 2017MaintBotReverted to version '10:43, 16 September 2016' by MaintBot
92243view22:15, 15 May 2017KrasinQuick edit to datanode annotation or property
89510view10:43, 16 September 2016Mkutmonontology tag fix
89467view13:38, 15 September 2016Mkutmonremove space from ontology term id
77402view22:36, 5 September 2014MaintBotremoved homology mapp label
71543view19:25, 17 October 2013MaintBotAutomated update of data sources
70074view09:13, 12 July 2013Mkutmonfixed unconnected lines
67084view10:04, 26 June 2013Christine ChichesterOntology Term : 'biogenic amine biosynthetic pathway' added !
62150view10:43, 25 April 2013EgonwConverted labels into Metabolite DataNode's.
62147view10:41, 25 April 2013EgonwThe applet changed the coordinate space, so when I copied in the unconverted metabolite locations... :( Undo revision 62146 by [[Special:Contributions/Egonw|Egonw]] ([[User talk:Egonw|Talk]])
62146view10:34, 25 April 2013EgonwConverted labels into Metabolite DataNode's.
62145view10:33, 25 April 2013EgonwConnected dots
40892view22:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
35163view14:41, 11 February 2010ThomasModified description
35162view14:41, 11 February 2010Thomasadded literature
34158view21:08, 9 December 2009MaintBotAutomatic update of empty xrefs
20945view11:30, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Biogenic Amine Synthesis]] moved to [[Pathway:WP125]]: Moved to stable identifier
8588view14:04, 7 January 2008MaintBotAdded to category $category
8586view14:04, 7 January 2008AlexanderPicoUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5-hydroxy-tryptophanMetabolite
AANATGeneProduct
ACHEGeneProduct
ASMTGeneProduct
AcetylcholineMetabolite
AcetylserotoninMetabolite
COMTGeneProduct47091 (Entrez Gene)
ChaGeneProduct42249 (Entrez Gene)
CholineMetabolite
DdcGeneProduct35190 (Entrez Gene)
DopamineMetabolite
EpinephrineMetabolite
GABAMetabolite
GAD2GeneProduct
Gad1GeneProduct38484 (Entrez Gene)
GlutamateMetabolite
HdcGeneProduct36076 (Entrez Gene)
HistamineMetabolite
HistidineMetabolite
HnGeneProduct38871 (Entrez Gene)
L-DOPAMetabolite
MAOAGeneProduct
MelatoninMetabolite
NorepinephrineMetabolite
PNMTGeneProduct
PhenylalanineMetabolite
SerotoninMetabolite
TbhGeneProduct31718 (Entrez Gene)
TrhGeneProduct38121 (Entrez Gene)
TryptophanMetabolite
TyrosineMetabolite
pleGeneProduct38746 (Entrez Gene)

Annotated Interactions

No annotated interactions

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