Tryptophan metabolism (Mus musculus)
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C00877
Cinnavalininate
Benzoate degradation via hydroxylation
4-(2-Amino-3-hydroxyphenyl)
-2,4-dioxobutanoate
Isophenoxazine
4-(2-Amino-5-hydroxyphenyl)
-2,4-dioxobutanoate
2-Oxoglutarate
N-Methyltryptamine
Glycolysis / Gluconeogenesis
Indolelactate
5-Hydroxy-N-formylkynurenine
4,6-Dihydroxyquinoline
3-Methyldioxyindole
3-Hydroxykynurenamine
L-Tryptophanyl-tRNA
Anthranilate
Anthranilate
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
5-Hydroxyindoleacetate
2-Formylaminobenzaldehyde
2-Oxoadipate
2-Formamino
benzoylacetate
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
Indole-3-acetate
Kynurenate
3-Indoleglycolaldehyde
5-Hydroxykynurenamine
(Z)-5-Oxohex-2-enedioate
3-Hydroxy-
L-kynurenine
C00527
5-Hydroxyindoleacetaldehyde
N-Methylserotonin
N-Acetylindoxyl
C00332
2-Amino-3-carboxymuconate
Melatonin
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate
2-Aminomuconate
3-(2-Aminoethyl)
-1H-indol-5-ol
6-Hydroxykynurenate
7,8-Dihydroxykynurenate
3-Methoxyanthranilate
3-Methylindolepyruvate
Glucobrassicin
C01144
5-Hydroxyindolepyruvate
Quinolinate
PhenylAla, Tyr and Trp biosynthesis
3-Hydroxyanthranilate
5-Hydroxy-
L-tryptophan
4,8-Dihydroxyquinoline
Oxaloacetate
Indole-3-acetaldoxime
Xanthurenic
Nicotinate and nicotinamide metabolism
4-(2-Aminophenyl)-2,4-dioxobutanoate
Formyl-5-hydroxykynurenamine
6-Hydroxyindolelactate
Indole-3-ethanol
8-Methoxykynurenate
Indole-3-acetaldehyde
2-Aminomuconate
2,3-Dihydroxyindole
5-Methoxyindoleacetate
Benzoate degradation via hydroxylation
Indolepyruvate
Formylanthranilate
7,8-Dihydro-7,8-dihydroxykynurenate
5-Hydroxyindoleacetylglycine
Formyl-N-acetyl-5-
methoxykynurenamine
Ido1
Tdo2
N-Acetylisatin
Cyp2f2
1.13.12.3
Prmt1
Aldh3a2
1.13.11.23
2.1.1.49
Aldh3a2
Kynu
Rnf25
Acat1
Tryptamine
Ddc
2-Aminophenol
1.1.1.190
Aadat
L-Tryptophan
Cyp2c12
Cyp2d2
N-Acetylserotonin
Formylkynurenine
1.1.1.191
3.2.1.147
3-Indoleacetonitrile
Tph1
3.5.1.9
3.5.1.4
L-Kynurenine
Maob
Aldh1a2
Kynu
Aox1
Prmt1
1.14.16.3
Aldh1a4
Dhcr24
Maob
Ogdh
2.6.1.27
1.5.1.-
Gcdh
Cyp2a1
Aadat
4.1.99.1
ASMT
Abp1
Mdm2
Cyp1a1
Cyp1a2
4.1.1.43
Maob
1.7.3.2
1.1.1.110
Aldh2
1.13.11.17
Aldh1a1
3.5.1.49
1.14.13.9
Ido1
ASMT
3.5.5.1
6-Hydroxymelatonin
Echs1
Hadh
1.14.99.2
Ido1
Indole
Ddc
Prmt1
Inmt
1.13.11.10
5-Hydroxykynurenine
3.5.99.5
5-Methoxytryptamine
Cyp2c55
1.3.1.18
1.13.11.-
Mdm2
1.2.1.32
2.1.1.47
Aldh1a1
Indole-3-acetamide
Aldh9a1
Cyp4f14
1.2.3.7
Kynu
Cyp19a1
Cyp7b1
Haao
Ubr5
Cyp2b15
Aldh2
Cyp2j6
Ube3a
Mdm2
Aldh1a2
4.2.1.84
Wars
4.1.1.-
1.13.99.3
Acetyl-CoA
2.6.1.27
Afmid
Ube3a
Maob
Cyp2a2
Aldh9a1
Cat
Cyp1b1
CYP3A4
1.4.3.2
Rnf25
Hsd17b10
Gcdh
Ddc
2.6.1.27
Aanat
CYP2A13
Acmsd
1.2.1.-
1.10.3.4
1.14.16.-
Cyp2e1
Aldh1a4
Description
No description
Comments
GenMAPP notes
Converted from rat to human using ortholog information. Link to original KEGG map:
http://www.genome.ad.jp/dbget-bin/show
pathway?rno00380
GenMAPP remarks
Edited by Sebastien Burel
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP465(r30270)
with a 57% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
128037
view
18:00, 21 January 2024
Eweitz
Upgrade label to identified pathway, fix some truncated labels
104913
view
19:21, 24 June 2019
Khanspers
Modified description
104912
view
19:21, 24 June 2019
Khanspers
removed genmapp comments
104819
view
12:55, 19 June 2019
Fehrhart
Modified description
91016
view
07:21, 21 December 2016
Egonw
One more ChemSpider ID update.
91009
view
00:38, 21 December 2016
AlexanderPico
updated deprecated chemspider id
91008
view
17:51, 20 December 2016
AlexanderPico
updated deprecated chemspider id
79761
view
07:02, 10 April 2015
Egonw
Replaced an incorrectly KEGG Compound formatted identifier with a ChEBI identifier.
76163
view
15:21, 13 June 2014
Egonw
Added a few missing metabolite identifiers.
73389
view
16:57, 25 January 2014
Egonw
Added a bunch of missing metabolite identifiers.
73231
view
20:11, 12 January 2014
Egonw
Added a bunch of missing metabolite identifiers.
72319
view
07:39, 3 November 2013
Egonw
Added a few metabolite identifiers.
71752
view
20:20, 17 October 2013
MaintBot
Automated update of data sources
71178
view
14:19, 11 October 2013
Egonw
Added metabolite identifiers.
70995
view
15:19, 22 September 2013
Egonw
Added ChemSpider and ChEBI identifiers for metabolites.
69193
view
18:23, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67726
view
11:55, 26 June 2013
Ddigles
Ontology Term : 'tryptophan metabolic pathway' added !
54741
view
13:17, 8 December 2012
Egonw
Replaced multiple general nodes by Metabolite DataNode's.
47759
view
05:02, 6 April 2012
Khanspers
updated xrefs
47756
view
04:53, 6 April 2012
Khanspers
updated xrefs
41384
view
00:29, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34424
view
23:19, 9 December 2009
MaintBot
Automatic update of empty xrefs
33468
view
15:04, 30 November 2009
MaintBot
Removed group label
31518
view
21:39, 13 August 2009
MaintBot
Fixed text labels
30850
view
00:07, 30 July 2009
MaintBot
Converted from Homo sapiens
20845
view
11:30, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Tryptophane Metabolism KEGG]] moved to [[Pathway:WP79]]: Moved to stable identifier
8466
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Tryptophane Metabolism KEGG]] moved to [[Pathway:Mus musculus:Tryptophane Metabolism KEGG]]: Renaming species
7849
view
16:23, 18 December 2007
MaintBot
fixed category names
7408
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
6506
view
22:19, 22 May 2007
L.M.Ferrante
gpml file for [[Mouse:Tryptophane_Metabolism_KEGG]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
(Z)-5-Oxohex-2-enedioate
Metabolite
CHEBI:16967 (ChEBI)
(Z)-5-Oxohex-2-enedioate
1.1.1.110
GeneProduct
1.1.1.190
GeneProduct
1.1.1.191
GeneProduct
1.10.3.4
GeneProduct
1.13.11.-
GeneProduct
1.13.11.10
GeneProduct
1.13.11.17
GeneProduct
1.13.11.23
GeneProduct
1.13.12.3
GeneProduct
1.13.99.3
GeneProduct
1.14.13.9
GeneProduct
1.14.16.-
GeneProduct
1.14.16.3
GeneProduct
1.14.99.2
GeneProduct
1.2.1.-
GeneProduct
1.2.1.32
GeneProduct
1.2.3.7
GeneProduct
1.3.1.18
GeneProduct
1.4.3.2
GeneProduct
1.5.1.-
GeneProduct
1.7.3.2
GeneProduct
2,3-Dihydroxyindole
Metabolite
CHEBI:17828 (ChEBI)
2-Amino-3-carboxymuconate
Metabolite
2-Amino-3-carboxymuconate
2-Aminomuconate
Metabolite
27 (Chemspider)
2-Aminomuconate
2-Aminophenol
Metabolite
CHEBI:18112 (ChEBI)
2-Aminophenol
2-Formamino benzoylacetate
Metabolite
2-Formaminobenzoylacetate
2-Formylaminobenzaldehyde
Metabolite
CHEBI:18033 (ChEBI)
2-Oxoadipate
Metabolite
70 (Chemspider)
2-Oxoadipate
2-Oxoglutarate
Metabolite
CHEBI:30916 (ChEBI)
2-Oxoglutarate
2.1.1.47
GeneProduct
2.1.1.49
GeneProduct
2.6.1.27
GeneProduct
3-(2-Aminoethyl) -1H-indol-5-ol
Metabolite
5202 (PubChem-compound)
3-(2-Aminoethyl)-1H-indol-5-ol
3-Hydroxy- L-kynurenine
Metabolite
CHEBI:17380 (ChEBI)
3-Hydroxy-L-kynurenine
3-Hydroxyanthranilate
Metabolite
7822291 (Chemspider)
3-Hydroxyanthranilate
3-Hydroxykynurenamine
Metabolite
144400 (Chemspider)
3-Hydroxykynurenamine
3-Indoleacetonitrile
Metabolite
CHEBI:17566 (ChEBI)
3-Indoleacetonitrile
3-Indoleglycolaldehyde
Metabolite
CHEBI:15976 (ChEBI)
3-Methoxyanthranilate
Metabolite
CHEBI:20109 (ChEBI)
3-Methoxyanthranilate
3-Methyldioxyindole
Metabolite
CHEBI:28254 (ChEBI)
3-Methylindolepyruvate
Metabolite
440740 (PubChem-compound)
3-Methylindolepyruvate
3.2.1.147
GeneProduct
3.5.1.4
GeneProduct
3.5.1.49
GeneProduct
3.5.1.9
GeneProduct
3.5.5.1
GeneProduct
3.5.99.5
GeneProduct
4,6-Dihydroxyquinoline
Metabolite
389609 (Chemspider)
4,6-Dihydroxyquinoline
4,8-Dihydroxyquinoline
Metabolite
CHEBI:28883 (ChEBI)
4,8-Dihydroxyquinoline
4-(2-Amino-3-hydroxyphenyl) -2,4-dioxobutanoate
Metabolite
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
4-(2-Amino-5-hydroxyphenyl) -2,4-dioxobutanoate
Metabolite
20016012 (Chemspider)
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate
4-(2-Aminophenyl)-2,4-dioxobutanoate
Metabolite
CHEBI:58147 (ChEBI)
4-(2-Aminophenyl)-2,4-dioxobutanoate
4.1.1.-
GeneProduct
4.1.1.43
GeneProduct
4.1.99.1
GeneProduct
4.2.1.84
GeneProduct
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
Metabolite
389619 (Chemspider)
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
Metabolite
389618 (Chemspider)
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin
Metabolite
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate
Metabolite
389620 (Chemspider)
5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
5-Hydroxy- L-tryptophan
Metabolite
CHEBI:17780 (ChEBI)
5-Hydroxy-L-tryptophan
5-Hydroxy-N-formylkynurenine
Metabolite
389615 (Chemspider)
5-Hydroxy-N-formylkynurenine
5-Hydroxyindoleacetaldehyde
Metabolite
74688 (PubChem-compound)
5-Hydroxyindoleacetaldehyde
5-Hydroxyindoleacetate
Metabolite
1826 (PubChem-compound)
5-Hydroxyindoleacetate
5-Hydroxyindoleacetylglycine
Metabolite
440806 (PubChem-compound)
5-Hydroxyindolepyruvate
Metabolite
389613 (Chemspider)
5-Hydroxykynurenamine
Metabolite
144400 (Chemspider)
5-Hydroxykynurenamine
5-Hydroxykynurenine
Metabolite
389616 (Chemspider)
5-Methoxyindoleacetate
Metabolite
18986 (PubChem-compound)
5-Methoxyindoleacetate
5-Methoxytryptamine
Metabolite
CHEBI:2089 (ChEBI)
6-Hydroxyindolelactate
Metabolite
CHEBI:27524 (ChEBI)
6-Hydroxyindolelactate
6-Hydroxykynurenate
Metabolite
20477287 (Chemspider)
6-Hydroxykynurenate
6-Hydroxymelatonin
Metabolite
1864 (PubChem-compound)
7,8-Dihydro-7,8-dihydroxykynurenate
Metabolite
388563 (Chemspider)
7,8-Dihydro-7,8-dihydroxykynurenate
7,8-Dihydroxykynurenate
Metabolite
CHEBI:58171 (ChEBI)
7,8-Dihydroxykynurenate
8-Methoxykynurenate
Metabolite
CHEBI:20109 (ChEBI)
8-Methoxykynurenate
ASMT
GeneProduct
107626 (Entrez Gene)
Aadat
GeneProduct
23923 (Entrez Gene)
Aanat
GeneProduct
11298 (Entrez Gene)
Abp1
GeneProduct
76507 (Entrez Gene)
Acat1
GeneProduct
110446 (Entrez Gene)
Acetyl-CoA
Metabolite
CHEBI:15351 (ChEBI)
Acetyl-CoA
Acmsd
GeneProduct
266645 (Entrez Gene)
Afmid
GeneProduct
71562 (Entrez Gene)
Aldh1a1
GeneProduct
11668 (Entrez Gene)
Aldh1a2
GeneProduct
19378 (Entrez Gene)
Aldh1a4
GeneProduct
Aldh2
GeneProduct
11669 (Entrez Gene)
Aldh3a2
GeneProduct
11671 (Entrez Gene)
Aldh9a1
GeneProduct
56752 (Entrez Gene)
Anthranilate
Metabolite
CHEBI:16567 (ChEBI)
Anthranilate
Aox1
GeneProduct
11761 (Entrez Gene)
C00332
Metabolite
C00332 (KEGG Compound)
Acetoacetyl-CoA
C00527
Metabolite
C00527 (KEGG Compound)
Glutaryl-CoA
C00877
Metabolite
C00877 (KEGG Compound)
Crotonoyl-CoA
C01144
Metabolite
C01144 (KEGG Compound)
(S)-3-Hydroxybutanoyl-CoA
CYP2A13
GeneProduct
CYP3A4
GeneProduct
Cat
GeneProduct
12359 (Entrez Gene)
Cinnavalininate
Metabolite
102864 (Chemspider)
Cinnavalininate
Cyp19a1
GeneProduct
13075 (Entrez Gene)
Cyp1a1
GeneProduct
13076 (Entrez Gene)
Cyp1a2
GeneProduct
13077 (Entrez Gene)
Cyp1b1
GeneProduct
13078 (Entrez Gene)
Cyp2a1
GeneProduct
Cyp2a2
GeneProduct
Cyp2b15
GeneProduct
Cyp2c12
GeneProduct
Cyp2c55
GeneProduct
72082 (Entrez Gene)
Cyp2d2
GeneProduct
Cyp2e1
GeneProduct
13106 (Entrez Gene)
Cyp2f2
GeneProduct
13107 (Entrez Gene)
Cyp2j6
GeneProduct
13110 (Entrez Gene)
Cyp4f14
GeneProduct
64385 (Entrez Gene)
Cyp7b1
GeneProduct
13123 (Entrez Gene)
Ddc
GeneProduct
13195 (Entrez Gene)
Dhcr24
GeneProduct
74754 (Entrez Gene)
predicted
Echs1
GeneProduct
93747 (Entrez Gene)
Formyl-5-hydroxykynurenamine
Metabolite
440743 (PubChem-compound)
Formyl-N-acetyl-5- methoxykynurenamine
Metabolite
171161 (PubChem-compound)
Formyl-N-acetyl-5-methoxykynurenamine
Formylanthranilate
Metabolite
CHEBI:18410 (ChEBI)
Formylanthranilate
Formylkynurenine
Metabolite
CHEBI:30249 (ChEBI)
Formylkynurenine
Gcdh
GeneProduct
270076 (Entrez Gene)
predicted
Glucobrassicin
Metabolite
CHEBI:29028 (ChEBI)
Glucobrassicin
Haao
GeneProduct
107766 (Entrez Gene)
Hadh
GeneProduct
15107 (Entrez Gene)
Hsd17b10
GeneProduct
15108 (Entrez Gene)
Ido1
GeneProduct
15930 (Entrez Gene)
Indole-3-acetaldehyde
Metabolite
CHEBI:18086 (ChEBI)
Indole-3-acetaldehyde
Indole-3-acetaldoxime
Metabolite
CHEBI:28311 (ChEBI)
Indole-3-acetaldoxime
Indole-3-acetamide
Metabolite
CHEBI:16031 (ChEBI)
Indole-3-acetamide
Indole-3-acetate
Metabolite
780 (Chemspider)
Indole-3-acetate
Indole-3-ethanol
Metabolite
10685 (PubChem-compound)
Indole
Metabolite
798 (PubChem-compound)
Indolelactate
Metabolite
92904 (PubChem-compound)
Indolelactate
Indolepyruvate
Metabolite
803 (PubChem-compound)
Indolepyruvate
Inmt
GeneProduct
21743 (Entrez Gene)
Isophenoxazine
Metabolite
65565 (Chemspider)
Isophenoxazine
Kynu
GeneProduct
70789 (Entrez Gene)
Kynurenate
Metabolite
CHEBI:18344 (ChEBI)
4-Hydroxy-2-quinolinecarboxylic
L-Kynurenine
Metabolite
CHEBI:16946 (ChEBI)
L-Kynurenine
L-Tryptophan
Metabolite
6305 (PubChem-compound)
L-Tryptophanyl-tRNA
Unknown
Maob
GeneProduct
109731 (Entrez Gene)
Mdm2
GeneProduct
17246 (Entrez Gene)
Melatonin
Metabolite
896 (PubChem-compound)
N-Acetylindoxyl
Metabolite
CHEBI:15363 (ChEBI)
N-Acetylindoxyl
N-Acetylisatin
Metabolite
CHEBI:16050 (ChEBI)
N-Acetylisatin
N-Acetylserotonin
Metabolite
CHEBI:17697 (ChEBI)
N-Acetylserotonin
N-Methylserotonin
Metabolite
150885 (PubChem-compound)
N-Methylserotonin
N-Methyltryptamine
Metabolite
CHEBI:28136 (ChEBI)
N-Methyltryptamine
Ogdh
GeneProduct
18293 (Entrez Gene)
Oxaloacetate
Metabolite
CHEBI:16452 (ChEBI)
Oxaloacetate
Prmt1
GeneProduct
15469 (Entrez Gene)
Quinolinate
Metabolite
2777129 (Chemspider)
Rnf25
GeneProduct
57751 (Entrez Gene)
Tdo2
GeneProduct
56720 (Entrez Gene)
Tph1
GeneProduct
21990 (Entrez Gene)
Tryptamine
Metabolite
CHEBI:16765 (ChEBI)
Ube3a
GeneProduct
22215 (Entrez Gene)
Ubr5
GeneProduct
70790 (Entrez Gene)
Wars
GeneProduct
22375 (Entrez Gene)
Xanthurenic
Metabolite
5497 (Chemspider)
Xanthurenic
Annotated Interactions
No annotated interactions
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