Alanine and aspartate metabolism (Bos taurus)
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1, 2
Protein
L-Alanyl-tRNA
Citrate cycle (TCA cycle)
Fatty acid metabolism
2.6.1.12
3.5.1.7
Selenoamino acid metabolism
4.1.1.12
2-Oxosuccinamate
ASL
Nicotinate and nicotinamide metabolism
Reductive carboxylate
cycle (CO2 fixation)
1.4.3.15
PC
2.6.1.14
Reductive carboxylate cycle (CO2 fixation)
beta-Alanine metabolism
Carnosine
Pyruvate
Lysine biosynthesis
Urea cycel and metabolism of amino groups
ASPA
4.3.1.1
Histidine metabolism
L-aspartate
DARS
N-Acetyl-L-aspartate
D-aspartate
4.3.2.2
L-Alanine
L-Asparagine
1.2.1.18
2.6.1.18
b-Alanine
L-Asparagine acid
Acetyl-CoA
5.1.1.13
Glycine, serine and threonine metabolism
DARS
L-Argininosuccinate
tRNA(Asp)
Pyrimidine metabolism
GPT
2.3.1.7
3.5.1.38
Succinate
3.5.1.1
6.3.5.4
6.1.1.22
6.3.4.4
4.1.1.11
Arginine and Proline metabolism
1.4.3.2
Cyanoamino acid metabolism
6.3.2.11
AGXT
Malonate semialdehyde
tRNA (Asn)
Glycolysis & gluconeogenesis
L-Asparagine acid
D-Ala metabolism
Malate
2.1.3.2
2-Oxoglutarate
Nicotinate and nicotinamide metabolism
1.4.3.1
Fumarate
6.3.5.6
N-Carbamoyl-L-aspartate
3.4.13.3
Adenylosuccinate
GAD1
GOT1
ASS1
Oxaloacetate
Pantothenate and CoA biosynthesis
tRNA (Asn)
O-Acetylcarnitine
ABAT
3.5.1.3
1.4.3.16
5.1.1.1
6.1.1.7
GAD2
L-Aspartic acid
GOT2
Citric acid
D-Alanine
6.3.1.1
Description
No description
Comments
GenMAPP notes
Converted from rat to human using ortholog information. Link to original KEGG map:
http://www.genome.ad.jp/dbget-bin/show
pathway?rno00252
GenMAPP remarks
Edited by Sebastien Burel.
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP106(74147)
with a 29.0% conversion rate.
Try the New WikiPathways
View approved pathways at
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Wu G; ''Intestinal mucosal amino acid catabolism.''; J Nutr, 1998
PubMed
Europe PMC
Scholia
Curien G, Bastien O, Robert-Genthon M, Cornish-Bowden A, Cárdenas ML, Dumas R; ''Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters.''; Mol Syst Biol, 2009
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
123267
view
09:07, 9 July 2022
Egonw
Made three pathways clickable
107073
view
14:16, 17 September 2019
MaintBot
ChEBI identifier normalization
105967
view
11:49, 16 August 2019
MaintBot
HMDB identifier normalization
102419
view
10:03, 23 December 2018
Egonw
Replaced a deleted CAS number with the active one.
92990
view
18:16, 21 July 2017
Khanspers
fixed unconnected
92989
view
18:11, 21 July 2017
Khanspers
Modified description
92988
view
18:10, 21 July 2017
Khanspers
removed GenMAPP notes
92895
view
19:09, 14 July 2017
Egonw
Replace a CAS number for a totally different compound with the ChEBI ID for L-alanine.
80904
view
15:30, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
1.2.1.18
GeneProduct
1.4.3.1
GeneProduct
1.4.3.15
GeneProduct
1.4.3.16
GeneProduct
1.4.3.2
GeneProduct
2-Oxoglutarate
Metabolite
C00026 (KEGG Compound)
2-Oxosuccinamate
Metabolite
2.1.3.2
GeneProduct
2.3.1.7
GeneProduct
2.6.1.12
GeneProduct
2.6.1.14
GeneProduct
2.6.1.18
GeneProduct
3.4.13.3
GeneProduct
3.5.1.1
GeneProduct
3.5.1.3
GeneProduct
3.5.1.38
GeneProduct
3.5.1.7
GeneProduct
4.1.1.11
GeneProduct
4.1.1.12
GeneProduct
4.3.1.1
GeneProduct
4.3.2.2
GeneProduct
5.1.1.1
GeneProduct
5.1.1.13
GeneProduct
6.1.1.22
GeneProduct
6.1.1.7
GeneProduct
6.3.1.1
GeneProduct
6.3.2.11
GeneProduct
6.3.4.4
GeneProduct
6.3.5.4
GeneProduct
6.3.5.6
GeneProduct
ABAT
GeneProduct
ENSBTAG00000004038 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:18
AGXT
GeneProduct
ENSBTAG00000005797 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:189
ASL
GeneProduct
ENSBTAG00000015314 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:435
ASPA
GeneProduct
ENSBTAG00000003629 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:443
ASS1
GeneProduct
ENSBTAG00000020747 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:445
Acetyl-CoA
Metabolite
72-89-9 (CAS)
Acetyl-CoA
Adenylosuccinate
Metabolite
Arginine and Proline metabolism
Pathway
Carnosine
Metabolite
305-84-0 (CAS)
Carnosine
Citric acid
Metabolite
HMDB00094 (HMDB)
Cyanoamino acid metabolism
Pathway
D-Ala metabolism
Pathway
D-Alanine
Metabolite
338-69-2 (CAS)
D-Alanine
D-aspartate
Metabolite
C00402 (KEGG Compound)
DARS
GeneProduct
ENSBTAG00000009949 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1615
Fatty acid metabolism
Pathway
WP143 (WikiPathways)
Fumarate
Metabolite
C00122 (KEGG Compound)
GAD1
GeneProduct
ENSBTAG00000007258 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2571
GAD2
GeneProduct
ENSBTAG00000008056 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2572
GOT1
GeneProduct
ENSBTAG00000011960 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2805
GOT2
GeneProduct
ENSBTAG00000007172 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2806
GPT
GeneProduct
ENSBTAG00000007835 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2875
Glycine, serine and threonine metabolism
Pathway
Glycolysis & gluconeogenesis
Pathway
WP534 (WikiPathways)
Histidine metabolism
Pathway
L-Alanine
Metabolite
CHEBI:16977 (ChEBI)
L-Argininosuccinate
Metabolite
CHEBI:15682 (ChEBI)
L-Asparagine acid
Metabolite
70-47-3 (CAS)
L-Asparagine
Metabolite
70-47-3 (CAS)
L-Asparagine
L-Aspartic acid
Metabolite
C00049 (KEGG Compound)
L-aspartate
Metabolite
C00049 (KEGG Compound)
Lysine biosynthesis
Pathway
Malate
Metabolite
617-48-1 (CAS)
(S)-Malate
Malonate semialdehyde
Metabolite
33190 (ChEBI)
N-Acetyl-L-aspartate
Metabolite
N-Carbamoyl-L-aspartate
Metabolite
15859 (ChEBI)
Nicotinate and nicotinamide metabolism
Pathway
O-Acetylcarnitine
Metabolite
3040-38-8 (CAS)
Oxaloacetate
Metabolite
C00036 (KEGG Compound)
PC
GeneProduct
ENSBTAG00000019700 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
Pantothenate and CoA biosynthesis
Pathway
Pyrimidine metabolism
Pathway
Pyruvate
Metabolite
32816 (ChEBI)
Reductive carboxylate cycle (CO2 fixation)
Pathway
Reductive carboxylate cycle (CO2 fixation)
Pathway
Selenoamino acid metabolism
Pathway
Succinate
Metabolite
C00042 (KEGG Compound)
Urea cycel and metabolism of amino groups
Pathway
WP497 (WikiPathways)
b-Alanine
Metabolite
6912-68-1 (CAS)
beta-alanine
beta-Alanine metabolism
Pathway
tRNA (Asn)
GeneProduct
tRNA(Asp)
GeneProduct
Annotated Interactions
No annotated interactions
Views
Pathway
Discussion
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No annotated interactions