PI3K-Akt signaling (Homo sapiens)

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GYS2CCND2CCNE1CCNE21-18, 20GYS1PPPPTSC2PPAntigenCytokineHypoxiaECMCytokineRChemokine SignalingPathwayPIP2VEGF SignalingPathwayNitric oxideFoxO SignalingPathwayAngiogenesisApoptosisITGA5Glycolysis and GluconeogenesisCell CycleCell proliferationInsulin SignalingPathwayJAK/STATSignaling PathwaymTOR SignalingPathwayFocal AdhesionErbB SignalingPathwayToll-like ReceptorSignaling PathwayDNA RepairB Cell Receptor Signaling PathwayPIP3AMPMAPK SignalingPathwayTSC1PPPIK3CACSF3GRB2JAK3JAK2EPOCOL4A2CHADITGB7TNRCOL4A5LAMB3IFNA1CSH1COMPCOL1A2ITGB4FN1THBS2IL3RAPIK3R1COL6A3AKT1PPPRELNPTK2LAMC3IL2RBIFNA4LAMC2IFNAR1LAMB1ITGA7ITGB6ITGA2BITGA9ITGA2PIK3R2COL4A6ITGA1OSMRDDIT4ITGA3TNCCOL6A6LAMA4ITGA8COL4A1LAMA3LAMC1LAMB2THBS4COL2A1JAK1PIK3CBTHBS3ITGA10ITGAVPRLRIL7RITGA6LAMA5IL6RITGB1IBSPCOL6A2VWFTNXBITGB5TNNSPP1PTENLAMA2CSF3RIL2RAEPORCOL6A1IL4RLAMA1SOS1ITGB3PIK3CDITGB8VTNTHBS1AKT3P19COL1A1COL4A3PIK3R3COL6A5IL2RGIFNA2IFNAR2COL4A4AKT2PPITGA4GHRITGA11PIK3R5EFNA1FGF1FGF11FGF10EFNA2EGFFGF12CSF1ANGPT4ANGPT2ANGPT1VEGFAEFNA3EFNA4EFNA5FGF14FGF5FGF19FGF17FGF18FGF2FGF3FGF4FGF6FGF7FGF8FGF9VEGFDHGFIGF1IGF2INSKITLGKik1b4FLT3LGVEGFCVEGFBPDGFBPGFPDGFANGFPDGFCFGF21FGF23FGF22PDGFDFGF20FGF13Growth FactorFGFR2KDRINSRFGFR3IGF1RKITFGFR1EPHA2EGFRCSF1RFGFR4FLT1FLT4NGFRMETPDGFRAPDGFRBTEKRTKIFNA5IFNA6IFNA7IFNA8IFNA10IFNA14IFNB1IL2OSMPRLIFNA13CHRM1LPAR1F2RCHRM2LPAR5LPAR2LPAR3LPAR6LPAR4GPCRGNB2GNB1GNB4GNGT1GNG10GNG12GNB3GByGNG2GNG3GNG4GNG5GNG7GNG8GNGT2GNG13GNG11PIK3CGNRASKRASHRASChemokines, Homones, NeurotransmittersPRKAA1PRKAA2MLST8RHEBMTORRPTORTHEM4CDC37HSP90AB1PHLPP1TCL1APDPK1PPP2CBPPP2CAPPP2R2APPP2R5DPPP2R5BPPP2R2BPPP2R1BPPP2R3BPPP2R3APPP2R5CPPP2R5EPPP2R2CPPP2R1APPP2R2DPPP2R5APPP2R3CHSP90AA1HSP90B1PHLPP2Mtcp1TCL1BRAF1MAP2K2MAP2K1MAPK1MAPK3GSK3BPFOXO3PPPPPPIKBKBPPBADPCASP9PMDM2PPPIKBKGPPCDKN1BPCDKN1APATF2CREB3CREB1PATF4CREB3L2CREB3L3ATF6BCREB3L1CREB3L4CREB5Cell SurvivalCell Cycle ProgressionProtein SynethesisMetabolism-pRPS6KB1PPPPPPPPRPS6KB2PPPEIF4EBP1PPPPEIF4BPRPS6PPEIF4EEIF4E2EIF4E1BIRS1PIK3R6CSH2GH1GH2IFNA16IFNA17IFNA21IL3IL4IL6IL7GNB5CD19PPIK3AP1BCRSYKTLR2TLR4Pathogen-associatedmolecular patterns(PAMPS)RAC1SOS2LAMB4COL9A1COL9A2COL9A3TP53CHUKNFKB1RELABCL2L1MYBFGF19NTF3NTF4BDNFTGFAFLT3NTRK1NTRK2STK11BCL2MCL1BCL2BCL2L1RBL2CDKN1BFASLGBCL2L11CDK2CDK4CDK6CCND1PCCND3PCK1PCK2G6PCG6PC2G6PC3MYCPPBRCA1PNOS3PRKCAPPPKN1PPKN2PPPPPKN3Glucose uptakeVesicle transportActin reorganizationC8orf44-SGK3SGK1PPSGK2PSGK3PSurvival signal,Growth and proliferation


Description

PI3K-Akt Signaling Pathway

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Bibliography

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  1. Blume-Jensen P, Hunter T; ''Oncogenic kinase signalling.''; Nature, 2001 PubMed Europe PMC Scholia
  2. Song G, Ouyang G, Bao S; ''The activation of Akt/PKB signaling pathway and cell survival.''; J Cell Mol Med, 2005 PubMed Europe PMC Scholia
  3. Okkenhaug K, Vanhaesebroeck B; ''PI3K in lymphocyte development, differentiation and activation.''; Nat Rev Immunol, 2003 PubMed Europe PMC Scholia
  4. Noguchi M, Ropars V, Roumestand C, Suizu F; ''Proto-oncogene TCL1: more than just a coactivator for Akt.''; FASEB J, 2007 PubMed Europe PMC Scholia
  5. Duronio V; ''The life of a cell: apoptosis regulation by the PI3K/PKB pathway.''; Biochem J, 2008 PubMed Europe PMC Scholia
  6. Hornbeck PV, Zhang B, Murray B, Kornhauser JM, Latham V, Skrzypek E; ''PhosphoSitePlus, 2014: mutations, PTMs and recalibrations.''; Nucleic Acids Res, 2015 PubMed Europe PMC Scholia
  7. Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR; ''Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.''; Biochem J, 1998 PubMed Europe PMC Scholia
  8. Hers I, Vincent EE, Tavaré JM; ''Akt signalling in health and disease.''; Cell Signal, 2011 PubMed Europe PMC Scholia
  9. Engelman JA, Luo J, Cantley LC; ''The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism.''; Nat Rev Genet, 2006 PubMed Europe PMC Scholia
  10. Richardson CJ, Schalm SS, Blenis J; ''PI3-kinase and TOR: PIKTORing cell growth.''; Semin Cell Dev Biol, 2004 PubMed Europe PMC Scholia
  11. West KA, Castillo SS, Dennis PA; ''Activation of the PI3K/Akt pathway and chemotherapeutic resistance.''; Drug Resist Updat, 2002 PubMed Europe PMC Scholia
  12. Koyasu S; ''The role of PI3K in immune cells.''; Nat Immunol, 2003 PubMed Europe PMC Scholia
  13. Skaper SD; ''The neurotrophin family of neurotrophic factors: an overview.''; Methods Mol Biol, 2012 PubMed Europe PMC Scholia
  14. Georgescu MM; ''PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control.''; Genes Cancer, 2010 PubMed Europe PMC Scholia
  15. Moelling K, Schad K, Bosse M, Zimmermann S, Schweneker M; ''Regulation of Raf-Akt Cross-talk.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
  16. Lemmon MA, Schlessinger J; ''Cell signaling by receptor tyrosine kinases.''; Cell, 2010 PubMed Europe PMC Scholia
  17. Zhang X, Tang N, Hadden TJ, Rishi AK; ''Akt, FoxO and regulation of apoptosis.''; Biochim Biophys Acta, 2011 PubMed Europe PMC Scholia
  18. Wymann MP, Pirola L; ''Structure and function of phosphoinositide 3-kinases.''; Biochim Biophys Acta, 1998 PubMed Europe PMC Scholia
  19. Kikani CK, Dong LQ, Liu F; ''"New"-clear functions of PDK1: beyond a master kinase in the cytosol?''; J Cell Biochem, 2005 PubMed Europe PMC Scholia
  20. Kim D, Chung J; ''Akt: versatile mediator of cell survival and beyond.''; J Biochem Mol Biol, 2002 PubMed Europe PMC Scholia
  21. Osaki M, Oshimura M, Ito H; ''PI3K-Akt pathway: its functions and alterations in human cancer.''; Apoptosis, 2004 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
137597view15:44, 5 March 2025EgonwModified description
134839view16:53, 27 July 2024Eweitz"CytokineR" -> "Cytokine receptor"
129658view00:38, 22 May 2024EweitzModified title
128769view23:08, 21 February 2024EweitzUpgrade disease node
128035view17:28, 21 January 2024EweitzFix typos, tailor node dimensions, standardize case
127493view18:34, 11 October 2023Khanspersupdated phosphosites, updated line type, corrected node height
127444view23:39, 2 October 2023Khanspersupdated phosphosites
127442view23:24, 2 October 2023Khanspersupdated AKT phospho sites
127243view00:26, 26 August 2023Khanspersadded lit ref and updated description
122580view16:46, 17 April 2022EgonwMade multiple pathways clickable
116400view00:03, 7 May 2021EweitzModified title
112040view20:02, 16 September 2020Khanspersupdated phosphosites
106781view13:26, 17 September 2019MaintBotHMDB identifier normalization
106516view21:14, 5 September 2019KhanspersModified description
105775view19:41, 15 August 2019KhanspersModified description
96453view11:31, 15 March 2018EgonwReplaced a secondary ChEBI identifier with a primary identifier.
95701view19:55, 18 January 2018KhanspersOntology Term : 'cell cycle pathway' added !
95695view19:49, 18 January 2018KhanspersModified description
95694view19:48, 18 January 2018KhanspersModified description
95693view19:48, 18 January 2018KhanspersModified description
95684view18:19, 18 January 2018AriuttaOntology Term : 'cancer pathway' added !
95683view18:18, 18 January 2018AriuttaOntology Term : 'cancer' added !
95682view18:08, 18 January 2018AriuttaModified description
95163view00:42, 18 November 2017KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProductENSG00000142208 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11651
AKT2GeneProductENSG00000105221 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11652
AKT3GeneProductENSG00000117020 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23797
AMPMetaboliteCHEBI:2356 (ChEBI)
ANGPT1GeneProductENSG00000154188 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11600
ANGPT2GeneProductENSG00000091879 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11601
ANGPT4GeneProductENSG00000101280 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11602
ATF2GeneProductENSG00000115966 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11909
ATF4GeneProductENSG00000128272 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11911
ATF6BGeneProductENSG00000213676 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12915
AngiogenesisPathwayWP1539 (WikiPathways)
ApoptosisPathwayWP254 (WikiPathways)
B Cell Receptor Signaling PathwayPathwayWP23 (WikiPathways)
BADGeneProductENSG00000002330 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12015
BCL2GeneProductENSG00000171791 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
BCL2L11GeneProductENSG00000153094 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
BCL2L1GeneProductENSG00000171552 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
BCRGeneProduct102723407 (Entrez Gene) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
BDNFGeneProductENSG00000176697 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785
BRCA1GeneProductENSG00000012048 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
C8orf44-SGK3GeneProductENSG00000270024 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
CASP9GeneProductENSG00000132906 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12371
CCND1GeneProductENSG00000110092 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CCND2GeneProductENSG00000118971 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CCND3GeneProductENSG00000112576 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CCNE1GeneProductENSG00000105173 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CCNE2GeneProductENSG00000175305 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CD19GeneProductENSG00000177455 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
CDC37GeneProductENSG00000105401 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12539
CDK2GeneProductENSG00000123374 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CDK4GeneProductENSG00000135446 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CDK6GeneProductENSG00000105810 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CDKN1AGeneProductENSG00000124762 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12575
CDKN1BGeneProductENSG00000111276 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
CHADGeneProductENSG00000136457 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12643
CHRM1GeneProductENSG00000168539 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12669
CHRM2GeneProductENSG00000181072 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:243764
CHUKGeneProductENSG00000213341 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151
COL1A1GeneProductENSG00000108821 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12842
COL1A2GeneProductENSG00000164692 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12843
COL2A1GeneProductENSG00000139219 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12824
COL4A1GeneProductENSG00000187498 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12826
COL4A2GeneProductENSG00000134871 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12827
COL4A3GeneProductENSG00000169031 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12814
COL4A4GeneProductENSG00000081052 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12829
COL4A5GeneProductENSG00000188153 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12815
COL4A6GeneProductENSG00000197565 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:94216
COL6A1GeneProductENSG00000142156 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12825
COL6A2GeneProductENSG00000142173 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12834
COL6A3GeneProductENSG00000163359 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12831
COL6A5GeneProductENSG00000172752 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867
COL6A6GeneProductENSG00000206384 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12832
COL9A1GeneProductENSG00000112280 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867
COL9A2GeneProductENSG00000049089 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867
COL9A3GeneProductENSG00000092758 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867
COMPGeneProductENSG00000105664 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12845
CREB1GeneProductENSG00000118260 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12912
CREB3GeneProductENSG00000107175 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12913
CREB3L1GeneProductENSG00000157613 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26427
CREB3L2GeneProductENSG00000182158 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208647
CREB3L3GeneProductENSG00000060566 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208677
CREB3L4GeneProductENSG00000143578 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78284
CREB5GeneProductENSG00000146592 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:231991
CSF1GeneProductENSG00000184371 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12977
CSF1RGeneProductENSG00000182578 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12978
CSF3GeneProductENSG00000108342 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12985
CSF3RGeneProductENSG00000119535 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
CSH1GeneProductENSG00000136488 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599
CSH2GeneProductENSG00000213218 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599
Cell CyclePathwayWP179 (WikiPathways)
Cell proliferationPathway
Chemokine Signaling PathwayPathwayWP3929 (WikiPathways)
DDIT4GeneProductENSG00000168209 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
DNA RepairPathwayWP707 (WikiPathways)
EFNA1GeneProductENSG00000169242 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13636
EFNA2GeneProductENSG00000099617 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13637
EFNA3GeneProductENSG00000143590 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13638
EFNA4GeneProductENSG00000243364 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13639
EFNA5GeneProductENSG00000184349 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640
EGFGeneProductENSG00000138798 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13645
EGFRGeneProductENSG00000146648 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13649
EIF4BGeneProductENSG00000063046 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75705
EIF4E1BGeneProductENSG00000175766 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:218268
EIF4E2GeneProductENSG00000135930 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26987
EIF4EBP1GeneProductENSG00000187840 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13685
EIF4EGeneProductENSG00000151247 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13684
EPHA2GeneProductENSG00000142627 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13836
EPOGeneProductENSG00000130427 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13856
EPORGeneProductENSG00000187266 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13857
ErbB Signaling PathwayPathwayWP673 (WikiPathways)
F2RGeneProductENSG00000181104 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14062
FASLGGeneProductENSG00000117560 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
FGF10GeneProductENSG00000070193 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14165
FGF11GeneProductENSG00000161958 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14166
FGF12GeneProductENSG00000114279 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14167
FGF13GeneProductENSG00000129682 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80903
FGF14GeneProductENSG00000102466 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14169
FGF17GeneProductENSG00000158815 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14171
FGF18GeneProductENSG00000156427 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172
FGF19GeneProductENSG00000162344 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172
FGF1GeneProductENSG00000113578 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14164
FGF20GeneProductENSG00000078579 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80857
FGF21GeneProductENSG00000105550 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56636
FGF22GeneProductENSG00000070388 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67112
FGF23GeneProductENSG00000118972 (Ensembl)
FGF2GeneProductENSG00000138685 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14173
FGF3GeneProductENSG00000186895 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14174
FGF4GeneProductENSG00000075388 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14175
FGF5GeneProductENSG00000138675 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14168
FGF6GeneProductENSG00000111241 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14177
FGF7GeneProductENSG00000140285 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14178
FGF8GeneProductENSG00000107831 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14179
FGF9GeneProductENSG00000102678 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14180
FGFR1GeneProductENSG00000077782 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14182
FGFR2GeneProductENSG00000066468 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14183
FGFR3GeneProductENSG00000068078 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14184
FGFR4GeneProductENSG00000160867 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14186
FLT1GeneProductENSG00000102755 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14254
FLT3GeneProductENSG00000122025 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257
FLT3LGGeneProductENSG00000090554 (Ensembl)
FLT4GeneProductENSG00000037280 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257
FN1GeneProductENSG00000115414 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14268
FOXO3GeneProductENSG00000118689 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56484
Focal AdhesionPathwayWP306 (WikiPathways)
FoxO Signaling PathwayPathway
G6PC2GeneProductENSG00000152254 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
G6PC3GeneProductENSG00000141349 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
G6PCGeneProductENSG00000131482 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
GH1GeneProductENSG00000259384 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599
GH2GeneProductENSG00000136487 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599
GHRGeneProductENSG00000112964 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14600
GNB1GeneProductENSG00000078369 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14688
GNB2GeneProductENSG00000172354 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14693
GNB3GeneProductENSG00000111664 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14695
GNB4GeneProductENSG00000114450 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14696
GNB5GeneProductENSG00000069966 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702
GNG10GeneProductENSG00000242616 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14700
GNG11GeneProductENSG00000127920 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:66066
GNG12GeneProductENSG00000172380 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14701
GNG13GeneProductENSG00000127588 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64337
GNG2GeneProductENSG00000186469 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702
GNG3GeneProductENSG00000162188 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14704
GNG4GeneProductENSG00000168243 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14706
GNG5GeneProductENSG00000174021 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14707
GNG7GeneProductENSG00000176533 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14708
GNG8GeneProductENSG00000167414 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14709
GNGT1GeneProductENSG00000127928 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14699
GNGT2GeneProductENSG00000167083 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14710
GRB2GeneProductENSG00000177885 (Ensembl)
  • GRB2; growth factor receptor-bound protein 2
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14784
GSK3BGeneProductENSG00000082701 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56637
GYS1GeneProductENSG00000104812 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
GYS2GeneProductENSG00000111713 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
Glycolysis and GluconeogenesisPathwayWP534 (WikiPathways)
HGFGeneProductENSG00000019991 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15234
HRASGeneProductENSG00000174775 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15461
HSP90AA1GeneProductENSG00000080824 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15519
HSP90AB1GeneProductENSG00000096384 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15516
HSP90B1GeneProductENSG00000166598 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22027
IBSPGeneProductENSG00000029559 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15891
IFNA10GeneProductENSG00000186803 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15972
IFNA13GeneProductENSG00000233816 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:404549
IFNA14GeneProductENSG00000228083 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974
IFNA16GeneProductENSG00000147885 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974
IFNA17GeneProductENSG00000234829 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974
IFNA1GeneProductENSG00000197919 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15962
IFNA21GeneProductENSG00000137080 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974
IFNA2GeneProductENSG00000188379 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15964
IFNA4GeneProductENSG00000236637 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15965
IFNA5GeneProductENSG00000147873 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15967
IFNA6GeneProductENSG00000120235 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15968
IFNA7GeneProductENSG00000214042 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15969
IFNA8GeneProductENSG00000120242 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15970
IFNAR1GeneProductENSG00000142166 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15975
IFNAR2GeneProductENSG00000159110 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15976
IFNB1GeneProductENSG00000171855 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15977
IGF1GeneProductENSG00000017427 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16000
IGF1RGeneProductENSG00000140443 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16001
IGF2GeneProductENSG00000167244 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16333
IKBKBGeneProductENSG00000104365 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16150
IKBKGGeneProductENSG00000269335 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151
IL2GeneProductENSG00000109471 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183
IL2RAGeneProductENSG00000134460 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16184
IL2RBGeneProductENSG00000100385 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16185
IL2RGGeneProductENSG00000147168 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16186
IL3GeneProductENSG00000164399 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183
IL3RAGeneProductENSG00000185291 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16188
IL4GeneProductENSG00000113520 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183
IL4RGeneProductENSG00000077238 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16190
IL6GeneProductENSG00000136244 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183
IL6RGeneProductENSG00000160712 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16194
IL7GeneProductENSG00000104432 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183
IL7RGeneProductENSG00000168685 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16197
INSGeneProductENSG00000254647 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16334
INSRGeneProductENSG00000171105 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16337
IRS1GeneProductENSG00000169047 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367
ITGA10GeneProductENSG00000143127 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000090210
ITGA11GeneProductENSG00000137809 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:319480
ITGA1GeneProductENSG00000213949 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105083
ITGA2BGeneProductENSG00000005961 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16399
ITGA2GeneProductENSG00000164171 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16398
ITGA3GeneProductENSG00000005884 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16400
ITGA4GeneProductENSG00000115232 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16401
ITGA5GeneProductENSG00000161638 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16402
ITGA6GeneProductENSG00000091409 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16403
ITGA7GeneProductENSG00000135424 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16404
ITGA8GeneProductENSG00000077943 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:241226
ITGA9GeneProductENSG00000144668 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:104099
ITGAVGeneProductENSG00000138448 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = M:MGI:96608
ITGB1GeneProductENSG00000150093 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16412
ITGB3GeneProductENSG00000259207 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16416
ITGB4GeneProductENSG00000132470 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:192897
ITGB5GeneProductENSG00000082781 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16419
ITGB6GeneProductENSG00000115221 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16420
ITGB7GeneProductENSG00000139626 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16421
ITGB8GeneProductENSG00000105855 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320910
Insulin Signaling PathwayPathwayWP481 (WikiPathways)
JAK/STAT Signaling PathwayPathwayWP2593 (WikiPathways)
JAK1GeneProductENSG00000162434 (Ensembl)
  • CAV1; caveolin 1 caveolae protein 22kD
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16451
JAK2GeneProductENSG00000096968 (Ensembl)
  • CAV2; caveolin 2
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16452
JAK3GeneProductENSG00000105639 (Ensembl)
  • CAV3; caveolin 3
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16453
KDRGeneProductENSG00000128052 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16542
KITGeneProductENSG00000157404 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16590
KITLGGeneProductENSG00000049130 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17311
KRASGeneProductENSG00000133703 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16653
Kik1b4GeneProduct
LAMA1GeneProductENSG00000101680 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16772
LAMA2GeneProductENSG00000196569 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16773
LAMA3GeneProductENSG00000053747 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024421
LAMA4GeneProductENSG00000112769 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16775
LAMA5GeneProductENSG00000130702 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16776
LAMB1GeneProductENSG00000091136 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16777
LAMB2GeneProductENSG00000172037 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16779
LAMB3GeneProductENSG00000196878 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16780
LAMB4GeneProductENSG00000091128 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867
LAMC1GeneProductENSG00000135862 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226519
LAMC2GeneProductENSG00000058085 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16782
LAMC3GeneProductENSG00000050555 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23928
LPAR1GeneProductENSG00000198121 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14745
LPAR2GeneProductENSG00000064547 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53978
LPAR3GeneProductENSG00000171517 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:65086
LPAR4GeneProductENSG00000147145 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78134
LPAR5GeneProductENSG00000184574 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381810
LPAR6GeneProductENSG00000139679 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67168
MAP2K1GeneProductENSG00000169032 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26395
MAP2K2GeneProductENSG00000126934 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26396
MAPK Signaling PathwayPathwayWP382 (WikiPathways)
MAPK1GeneProductENSG00000100030 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26413
MAPK3GeneProductENSG00000102882 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26417
MCL1GeneProductENSG00000143384 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
MDM2GeneProductENSG00000135679 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
METGeneProductENSG00000105976 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17295
MLST8GeneProductENSG00000167965 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56716
MTORGeneProductENSG00000198793 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56717
MYBGeneProductENSG00000118513 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
MYCGeneProductENSG00000136997 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
Mtcp1GeneProductMultiple homologues found: En:ENSG00000214827;En:ENSG00000182712;
NFKB1GeneProductENSG00000109320 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
NGFGeneProductENSG00000134259 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18049
NGFRGeneProductENSG00000064300 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18053
NOS3GeneProductENSG00000164867 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
NRASGeneProductENSG00000213281 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18176
NTF3GeneProductENSG00000185652 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654
NTF4GeneProductENSG00000225950 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654
NTRK1GeneProductENSG00000198400 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687
NTRK2GeneProductENSG00000148053 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687
Nitric oxideMetaboliteHMDB03378 (HMDB)
OSMGeneProductENSG00000099985 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18413
OSMRGeneProductENSG00000145623 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18414
PCK1GeneProductENSG00000124253 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
PCK2GeneProductENSG00000100889 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
PDGFAGeneProductENSG00000197461 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18590
PDGFBGeneProductENSG00000100311 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18591
PDGFCGeneProductENSG00000145431 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:54635
PDGFDGeneProductENSG00000170962 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785
PDGFRAGeneProductENSG00000134853 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18595
PDGFRBGeneProductENSG00000113721 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18596
PDPK1GeneProductENSG00000140992 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18607
PGFGeneProductENSG00000119630 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654
PHLPP1GeneProductENSG00000081913 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:98432
PHLPP2GeneProductENSG00000040199 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:244650
PIK3AP1GeneProductENSG00000155629 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
PIK3CAGeneProductENSG00000121879 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18706
PIK3CBGeneProductENSG00000051382 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74769
PIK3CDGeneProductENSG00000171608 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18707
PIK3CGGeneProductENSG00000105851 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:30955
PIK3R1GeneProductENSG00000145675 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18708
PIK3R2GeneProductENSG00000105647 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18709
PIK3R3GeneProductENSG00000117461 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75669
PIK3R5GeneProductENSG00000141506 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207
PIK3R6GeneProductENSG00000276231 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207
PIP2MetaboliteCHEBI:18348 (ChEBI)
PIP3MetaboliteHMDB04249 (HMDB)
PKN1GeneProductENSG00000123143 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
PKN2GeneProductENSG00000065243 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
PKN3GeneProductENSG00000160447 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
PPP2CAGeneProductENSG00000113575 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19052
PPP2CBGeneProductENSG00000104695 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19053
PPP2R1AGeneProductENSG00000105568 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:51792
PPP2R1BGeneProductENSG00000137713 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:73699
PPP2R2AGeneProductENSG00000221914 (Ensembl)
PPP2R2BGeneProductENSG00000156475 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72930
PPP2R2CGeneProductENSG00000074211 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269643
PPP2R2DGeneProductENSG00000175470 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:52432
PPP2R3AGeneProductENSG00000073711 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:235542
PPP2R3BGeneProductENSG00000167393 (Ensembl)
PPP2R3CGeneProductENSG00000092020 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59032
PPP2R5AGeneProductENSG00000066027 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226849
PPP2R5BGeneProductENSG00000068971 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:225849
PPP2R5CGeneProductENSG00000078304 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26931
PPP2R5DGeneProductENSG00000112640 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21770
PPP2R5EGeneProductENSG00000154001 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26932
PRKAA1GeneProductENSG00000132356 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105787
PRKAA2GeneProductENSG00000162409 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:108079
PRKCAGeneProductENSG00000154229 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
PRLGeneProductENSG00000172179 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19109
PRLRGeneProductENSG00000113494 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19116
PTENGeneProductENSG00000171862 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19211
PTK2GeneProductENSG00000169398 (Ensembl)
  • DOCK1; dedicator of cyto-kinesis
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14083
RAC1GeneProductENSG00000136238 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367
RAF1GeneProductENSG00000132155 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:110157
RBL2GeneProductENSG00000103479 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
RELAGeneProduct5970 (Entrez Gene)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
RELNGeneProductENSG00000189056 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19699
RHEBGeneProductENSG00000106615 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19744
RPS6GeneProductENSG00000137154 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20104
RPS6KB1GeneProductENSG00000108443 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72508
RPS6KB2GeneProductENSG00000175634 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:58988
RPTORGeneProductENSG00000141564 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74370
SGK1GeneProductENSG00000118515 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
SGK2GeneProductENSG00000101049 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
SGK3GeneProductENSG00000104205 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
SOS1GeneProductENSG00000115904 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662
SOS2GeneProductENSG00000100485 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662
SPP1GeneProductENSG00000118785 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20750
STK11GeneProductENSG00000118046 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
SYKGeneProductENSG00000165025 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
TCL1AGeneProductENSG00000100721 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21432
TCL1BGeneProductENSG00000213231 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27379
TEKGeneProductENSG00000120156 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687
TGFAGeneProductENSG00000163235 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640
THBS1GeneProductENSG00000137801 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21825
THBS2GeneProductENSG00000186340 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21826
THBS3GeneProductENSG00000169231 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21827
THBS4GeneProductENSG00000113296 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21828
THEM4GeneProductENSG00000159445 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74343
TLR2GeneProductENSG00000137462 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
TLR4GeneProductENSG00000136869 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
TNCGeneProductENSG00000041982 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21923
TNNGeneProductENSG00000120332 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:329278
TNRGeneProductENSG00000116147 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21960
TNXBGeneProductENSG00000168477 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:81877
TP53GeneProductENSG00000141510 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
TSC1GeneProductENSG00000165699 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64930
TSC2GeneProductENSG00000103197 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22084
Toll-like Receptor Signaling PathwayPathwayWP75 (WikiPathways)
VEGF Signaling PathwayPathwayWP3888 (WikiPathways)
VEGFAGeneProductENSG00000112715 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22339
VEGFBGeneProductENSG00000173511 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22340
VEGFCGeneProductENSG00000150630 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22341
VEGFDGeneProductENSG00000165197 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14205
VTNGeneProductENSG00000109072 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22370
VWFGeneProductENSG00000110799 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22371
mTOR Signaling PathwayPathway

Annotated Interactions

No annotated interactions

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