G13 signaling pathway (Bos taurus)

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1Anti-ApoptoticGActin ReorganizationCell-Cell AdhesionActivated Rho AActin PolymerizationContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber Contraction13Disassembly of ActinStress FiberDisappearanceCytokinesisActin PolymerizationFilopodia FormationMembrane RufflingARHGEF1PIK3CBRHPN2FCHSD1SH3RF1CYFIP1IQGAP1ARHGDIGPIK3CDRHOAARHGDIBROCK1PIK3R2IQGAP2CFL1WASLRTKNGNA13CITRPS6KB1LIMK1WASMAPK10CFL2PIK3CAPAK3ROCK2MYL1MAP3K4PFN1MYBPHCDC42PKN1PPP1CBTNK2CALM1PIP4K2ARAC1


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP524 (r95116) with a 92.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117519view11:08, 21 May 2021EweitzModified title
95752view14:07, 19 January 2018MkutmonHomology conversion update
80871view15:29, 30 June 2015Mkutmonhomology conversion
72019view12:39, 24 October 2013Mkutmonfixed unconnected lines
71394view19:00, 17 October 2013MaintBotAutomated update of data sources
67273view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
63313view21:05, 9 May 2013MaintBotUpdated to 2013 gpml schema
62700view23:16, 1 May 2013MaintBotUpdated UniProt data source
40494view19:28, 1 March 2011MaintBotRemoved redundant pathway information and comments
35421view10:44, 12 February 2010ThomasModified description
35420view10:44, 12 February 2010Thomasadded literature, fixed connection
33738view23:55, 8 December 2009MaintBotAutomatic update of empty xrefs
32521view12:56, 17 August 2009MaintBotFixed text labels
32370view16:35, 15 August 2009MaintBotFixed text labels
32208view12:41, 15 August 2009MaintBotFixed text labels
31696view11:48, 14 August 2009MaintBotFixed group labels
31219view19:41, 13 August 2009MaintBotFixed text labels
30632view22:26, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIBGeneProductENSBTAG00000006039 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:397
ARHGDIGGeneProductENSBTAG00000027854 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:398
ARHGEF1GeneProductENSBTAG00000018912 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:9138
CALM1GeneProductNo homologues found for original id L:801
CDC42GeneProductNo homologues found for original id L:998
CFL1GeneProductNo homologues found for original id L:1072
CFL2GeneProductENSBTAG00000015053 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:1073
CITGeneProductENSBTAG00000008963 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:11113
CYFIP1GeneProductENSBTAG00000016894 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:23191
FCHSD1GeneProductENSBTAG00000030499 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:1729
GNA13GeneProductENSBTAG00000046174 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10672
IQGAP1GeneProductENSBTAG00000013060 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:8826
IQGAP2GeneProductENSBTAG00000000897 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10788
LIMK1GeneProductENSBTAG00000044083 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:3984
MAP3K4GeneProductENSBTAG00000020079 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4216
MAPK10GeneProductENSBTAG00000020048 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5602
MYBPHGeneProductENSBTAG00000011465 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4608
MYL1GeneProductENSBTAG00000009707 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4632
PAK3GeneProductENSBTAG00000015670 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5063
PFN1GeneProductENSBTAG00000018312 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5216
PIK3CAGeneProductENSBTAG00000009232 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5290
PIK3CBGeneProductENSBTAG00000006909 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5291
PIK3CDGeneProductENSBTAG00000018984 (Ensembl)
  • P42338
  • Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5293
PIK3R2GeneProductENSBTAG00000002350 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5296
PIP4K2AGeneProductENSBTAG00000018033 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5305
PKN1GeneProductENSBTAG00000017037 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5585
PPP1CBGeneProductENSBTAG00000012447 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5500
RAC1GeneProductENSBTAG00000009233 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5879
RHOAGeneProductENSBTAG00000004279 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:387
RHPN2GeneProductENSBTAG00000003089 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:85415
ROCK1GeneProductENSBTAG00000008403 (Ensembl)
  • S69211
  • Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6093
ROCK2GeneProductENSBTAG00000005847 (Ensembl)
  • BAA31594
  • Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:9475
RPS6KB1GeneProductENSBTAG00000016851 (Ensembl)
  • A41687
  • Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6198
RTKNGeneProductENSBTAG00000000490 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6242
SH3RF1GeneProductENSBTAG00000001508 (Ensembl)
  • Posh
  • Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:57630
TNK2GeneProductENSBTAG00000021364 (Ensembl)
  • S33596
  • Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10188
WASGeneProductENSBTAG00000046555 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:7454
WASLGeneProductENSBTAG00000004643 (Ensembl) Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:8976

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1063"
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