G13 signaling pathway (Danio rerio)

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1Disassembly of ActinStress FiberDisappearanceAnti-ApoptoticMembrane RufflingGActivated Rho AContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber Contraction13CytokinesisActin ReorganizationCell-Cell AdhesionActin PolymerizationFilopodia FormationActin Polymerizationpip4k2abrps6kb1agna13aPAK3mybphblimk1apik3caarhgef1bCFL1PPP1CCcyfip1waslbsi:dkey-40c11.1pik3cbmap3k4rac1bpik3r2tnk2awasapfn1pik3cdcalm1bcfl2DIAPH1ARHGDIGrock1iqgap2arhgdigrhoabcitbrhpn2myl1cdc42l2iqgap1pkn1bsh3rf1mapk10rock2a


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP524 (r95116) with a 89.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116876view10:56, 15 May 2021EweitzModified title
95753view14:07, 19 January 2018MkutmonHomology conversion update
77431view12:09, 8 September 2014Mkutmonupdated gene labes and some xrefs
72021view12:41, 24 October 2013Mkutmonfixed unconnected lines
71517view19:22, 17 October 2013MaintBotAutomated update of data sources
68648view05:02, 6 July 2013MaintBotUpdated to 2013 gpml schema
67275view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
62789view16:32, 2 May 2013MaintBotUpdated UniProt data source
40816view22:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
35426view10:54, 12 February 2010ThomasModified description
35425view10:53, 12 February 2010Thomasremoved braces, fixed labels, added literature
34204view21:29, 9 December 2009MaintBotAutomatic update of empty xrefs
32372view16:44, 15 August 2009MaintBotFixed text labels
32341view13:34, 15 August 2009MaintBotFixed text labels
31957view13:04, 14 August 2009MaintBotFixed group labels
31387view20:44, 13 August 2009MaintBotFixed text labels
31093view01:38, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIGGeneProductNo homologues found for original id L:398
CFL1GeneProductNo homologues found for original id L:1072
DIAPH1GeneProductNo homologues found for original id L:1729
PAK3GeneProductNo homologues found for original id L:5063
PPP1CCGeneProductENSDARG00000099226 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5500
arhgdigGeneProductENSDARG00000004034 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:397
arhgef1bGeneProductENSDARG00000055837 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:9138
calm1bGeneProductENSDARG00000034187 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:801
cdc42l2GeneProductENSDARG00000057869 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:998
cfl2GeneProductENSDARG00000014106 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:1073
citbGeneProductENSDARG00000088825 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:11113
cyfip1GeneProductENSDARG00000044345 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:23191
gna13aGeneProductENSDARG00000073765 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:10672
iqgap1GeneProductENSDARG00000078888 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:8826
iqgap2GeneProductENSDARG00000060010 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:10788
limk1aGeneProductENSDARG00000103467 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:3984
map3k4GeneProductENSDARG00000104835 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:4216
mapk10GeneProductENSDARG00000102730 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5602
mybphbGeneProductENSDARG00000003081 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:4608
myl1GeneProductENSDARG00000014196 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:4632
pfn1GeneProductENSDARG00000088091 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5216
pik3caGeneProductENSDARG00000075456 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5290
pik3cbGeneProductENSDARG00000075253 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5291
pik3cdGeneProductENSDARG00000003250 (Ensembl)
  • P42338
  • Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5293
pik3r2GeneProductENSDARG00000018060 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5296
pip4k2abGeneProductENSDARG00000063544 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5305
pkn1bGeneProductENSDARG00000062748 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5585
rac1bGeneProductENSDARG00000087954 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:5879
rhoabGeneProductENSDARG00000094673 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:387
rhpn2GeneProductENSDARG00000014577 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:85415
rock1GeneProductENSDARG00000058993 (Ensembl)
  • S69211
  • Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:6093
rock2aGeneProductENSDARG00000017500 (Ensembl)
  • BAA31594
  • Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:9475
rps6kb1aGeneProductENSDARG00000018399 (Ensembl)
  • A41687
  • Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:6198
sh3rf1GeneProductENSDARG00000070470 (Ensembl)
  • Posh
  • Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:57630
si:dkey-40c11.1GeneProductENSDARG00000031345 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:6242
tnk2aGeneProductENSDARG00000090646 (Ensembl)
  • S33596
  • Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:10188
wasaGeneProductENSDARG00000015149 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:7454
waslbGeneProductENSDARG00000006283 (Ensembl) Homology Mapping from Homo sapiens to Danio rerio: Original ID = L:8976

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1381"
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