Electron transport chain (Rattus norvegicus)

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Complex IIIntermembraneSpaceSuccinate-UbiquinoneOxidoreductasebinds ATP Synthase betaF1 ComplexComplex IAdenine NucleotideTranslocatorNADH-UbiquinoneOxidoreductaseUncoupling ProteinMatrixCytochrome COxidaseC subunitComplex IIIStalkAssemblyComplex VATP Synthase F0 ComplexUbiquinol-Cytochrome CReductaseComplex IVNdufb5Cox5aNdufa5Cox4i1Ndufb6Cox6a1Ndufa1Slc25a5Surf4Cox7a1Atp5g2Cox6b1ATPe-UqcrbUqcr10Ndufa7FADNdufc1Cytochrome CO2Mt-nd6LOC100361879TCA CycleH+Ndufb10H+Ndufab1Cox7bLOC100362798Cox15Ndufs1Mt-cybSLC25A6Uqcrfs1Mt-nd3Ndufb2Ndufa12Ndufb8ATP5A1COX11Atp5sNdufv2Ndufa10LOC684509LOC100911417Atp5j2LOC103694107AC096404.1Ndufb9Ndufa2H+H+Mt-nd5Ndufs4SdhcUqcrc2H+Ndufv1Slc25a4Atp5oAtp5bMt-atp8Cox6a2Cox17FADH2Cox8aNDUFB1Ndufb7Atp5hSlc25a14UbiquinoneSdhdMt-atp6SdhbUcp1COX7A3Ndufa6H2ONdufa9SdhaNADHNdufs8Ndufs2Cox6cLOC100363268Mt-nd4lMt-co1Cox7a2lNdufa4e-Slc25a27Atp5dSuccinateNAD+Atpif1Ndufs7LOC679739Atp5lH+ATP5C1Ndufv3Mt-nd1H+e-Sco1Mt-nd2Mt-nd4ATP5G1Ndufc2Ndufs3Atp5jMt-cox3Atp5iNdufa8Uqcrc1Ndufb4COX7CUqcrhUqcrqUcp2Mt-co2Atp5g3Cox7a2Ucp3


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP111 (r95118) with a 93.0% conversion rate.

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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
128031view17:04, 21 January 2024EweitzRefine orthologs, remove those missing in rat; all WikiPathways content is CC0
128030view16:52, 21 January 2024EweitzAdjust label positions to mitigate occlusion
128029view16:50, 21 January 2024EweitzRefine layout, standardize case
116956view10:07, 16 May 2021EweitzModified title
113947view06:14, 11 December 2020EgonwAnother clickable pathway
109405view17:43, 16 March 2020L DupuisFixed interaction
107001view13:45, 17 September 2019MaintBotHMDB identifier normalization
95793view14:40, 19 January 2018MkutmonHomology conversion update
79221view13:42, 15 March 2015EgonwReplaced the HMDB H2 identifier with H+ from ChEBI.
71772view20:30, 17 October 2013MaintBotAutomated update of data sources
71294view16:57, 17 October 2013MaintBotAutomated update of data sources
69341view18:51, 8 July 2013MaintBotUpdated to 2013 gpml schema
68397view07:38, 5 July 2013EgonwRemoved HMDB as data source where no identifier was given.
67193view10:19, 26 June 2013Christine ChichesterOntology Term : 'electron transport chain pathway' added !
62844view05:03, 3 May 2013MaintBotUpdated UniProt data source
41653view02:34, 2 March 2011MaintBotRemoved redundant pathway information and comments
38664view14:02, 23 September 2010FerryJagersLinked TCA Cycle
35241view19:46, 11 February 2010AlexanderPicoModified description
34051view19:02, 9 December 2009MaintBotAutomatic update of empty xrefs
32473view17:31, 15 August 2009MaintBotFixed text labels
32162view14:05, 14 August 2009MaintBotFixed group labels
31481view21:24, 13 August 2009MaintBotFixed text labels
30948view00:42, 30 July 2009MaintBotConverted from Homo sapiens
20801view11:29, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Electron Transport Chain]] moved to [[Pathway:WP59]]: Moved to stable identifier
8012view13:46, 7 January 2008MaintBot[[Pathway:Rat:Electron Transport Chain]] moved to [[Pathway:Rattus norvegicus:Electron Transport Chain]]: Renaming species
7629view16:05, 18 December 2007MaintBotfixed category names
7342view12:42, 4 November 2007MaintBotAdded categories to GPML
19423view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:Electron_Transport_Chain]]
6534view22:20, 22 May 2007Kdahlquistgpml file for [[Rat:Electron_Transport_Chain]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AC096404.1GeneProductENSRNOG00000000574 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1329
ATP5A1GeneProductENSRNOG00000054846 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:498
ATP5C1GeneProductNo homologues found for original id L:509
ATP5G1GeneProductNo homologues found for original id L:516
ATPMetaboliteC00002 (KEGG Compound)
Atp5bGeneProductENSRNOG00000002840 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:506
Atp5dGeneProductENSRNOG00000014625 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:513
Atp5g2GeneProductENSRNOG00000015320 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:517
Atp5g3GeneProductENSRNOG00000001596 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:518
Atp5hGeneProductENSRNOG00000003626 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10476
Atp5iGeneProductENSRNOG00000000064 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:521
Atp5j2GeneProductENSRNOG00000027049 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9551
Atp5jGeneProductENSRNOG00000001551 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:522
Atp5lGeneProductENSRNOG00000028884 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10632
Atp5oGeneProductENSRNOG00000001991 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:539
Atp5sGeneProductENSRNOG00000004893 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:27109
Atpif1GeneProductENSRNOG00000013300 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:93974
COX11GeneProductMultiple homologues found: En:ENSRNOG00000002474;En:ENSRNOG00000052096;
COX7A3GeneProduct
COX7CGeneProduct
Cox15GeneProductENSRNOG00000017230 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1355
Cox17GeneProductENSRNOG00000038951 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10063
Cox4i1GeneProductENSRNOG00000017817 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1327
Cox5aGeneProductENSRNOG00000018816 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9377
Cox6a1GeneProductENSRNOG00000001170 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1337
Cox6a2GeneProductENSRNOG00000019851 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1339
Cox6b1GeneProductENSRNOG00000024309 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1340
Cox6cGeneProductENSRNOG00000010807 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1345
Cox7a1GeneProductENSRNOG00000047364 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1346
Cox7a2GeneProductENSRNOG00000042903 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1347
Cox7a2lGeneProductENSRNOG00000004526 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9167
Cox7bGeneProductENSRNOG00000054689 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1349
Cox8aGeneProductENSRNOG00000021177 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1351
Cytochrome CMetaboliteC00524 (KEGG Compound)
FADMetaboliteC00016 (KEGG Compound)
FADH2MetaboliteC01352 (KEGG Compound)
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteHMDB02111 (HMDB)
LOC100361879GeneProductENSRNOG00000045749 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:514
LOC100362798GeneProductENSRNOG00000026875 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10975
LOC100363268GeneProductENSRNOG00000029339 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4725
LOC100911417GeneProductENSRNOG00000016000 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:515
LOC103694107GeneProductENSRNOG00000048888 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4709
LOC679739GeneProductENSRNOG00000023387 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4726
LOC684509GeneProductENSRNOG00000050514 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4696
Mt-atp6GeneProductENSRNOG00000031979 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4508
Mt-atp8GeneProductENSRNOG00000033299 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4509
Mt-co1GeneProductENSRNOG00000034234 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4512
Mt-co2GeneProductENSRNOG00000030371 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4513
Mt-cox3GeneProductENSRNOG00000030700 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4514
Mt-cybGeneProductENSRNOG00000031766 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4519
Mt-nd1GeneProductENSRNOG00000030644 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4535
Mt-nd2GeneProductENSRNOG00000031033 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4536
Mt-nd3GeneProductENSRNOG00000033615 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4537
Mt-nd4GeneProductENSRNOG00000029707 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4538
Mt-nd4lGeneProductENSRNOG00000031053 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4539
Mt-nd5GeneProductENSRNOG00000029971 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4540
Mt-nd6GeneProductENSRNOG00000029042 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4541
NAD+MetaboliteC00003 (KEGG Compound)
NADHMetaboliteC00004 (KEGG Compound)
NDUFB1GeneProductNo homologues found for original id L:4707
Ndufa10GeneProductENSRNOG00000016470 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4705
Ndufa12GeneProductENSRNOG00000007407 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:55967
Ndufa1GeneProductENSRNOG00000052226 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4694
Ndufa2GeneProductENSRNOG00000017571 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4695
Ndufa4GeneProductENSRNOG00000005512 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4697
Ndufa5GeneProductENSRNOG00000005698 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4698
Ndufa6GeneProductENSRNOG00000008569 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4700
Ndufa7GeneProductENSRNOG00000006939 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4701
Ndufa8GeneProductENSRNOG00000005668 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4702
Ndufa9GeneProductENSRNOG00000061684 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4704
Ndufab1GeneProductENSRNOG00000018129 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4706
Ndufb10GeneProductENSRNOG00000014568 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4716
Ndufb2GeneProductENSRNOG00000026616 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4708
Ndufb4GeneProductENSRNOG00000002721 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4710
Ndufb5GeneProductENSRNOG00000011949 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4711
Ndufb6GeneProductENSRNOG00000024539 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4712
Ndufb7GeneProductENSRNOG00000028717 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4713
Ndufb8GeneProductENSRNOG00000014078 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4714
Ndufb9GeneProductENSRNOG00000009364 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4715
Ndufc1GeneProductENSRNOG00000038218 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4717
Ndufc2GeneProductENSRNOG00000012383 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4718
Ndufs1GeneProductENSRNOG00000011849 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4719
Ndufs2GeneProductENSRNOG00000038372 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4720
Ndufs3GeneProductENSRNOG00000009155 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4722
Ndufs4GeneProductENSRNOG00000011383 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4724
Ndufs7GeneProductENSRNOG00000024568 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:374291
Ndufs8GeneProductENSRNOG00000017446 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4728
Ndufv1GeneProductENSRNOG00000018117 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4723
Ndufv2GeneProductENSRNOG00000042503 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4729
Ndufv3GeneProductENSRNOG00000001182 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4731
O2MetaboliteHMDB01377 (HMDB)
SLC25A6GeneProductNo homologues found for original id L:293
Sco1GeneProductENSRNOG00000028699 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6341
SdhaGeneProductENSRNOG00000013331 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6389
SdhbGeneProductENSRNOG00000007967 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6390
SdhcGeneProductENSRNOG00000003163 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6391
SdhdGeneProductENSRNOG00000022980 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6392
Slc25a14GeneProductENSRNOG00000006871 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9016
Slc25a27GeneProductENSRNOG00000010592 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9481
Slc25a4GeneProductENSRNOG00000010830 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:291
Slc25a5GeneProductENSRNOG00000039980 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:292
SuccinateMetaboliteC00042 (KEGG Compound)
Surf4GeneProductENSRNOG00000060005 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6834
TCA CyclePathwayWP78 (WikiPathways)
UbiquinoneMetaboliteHMDB02012 (HMDB)
Ucp1GeneProductENSRNOG00000003580 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7350
Ucp2GeneProductENSRNOG00000017854 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7351
Ucp3GeneProductENSRNOG00000017716 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7352
Uqcr10GeneProductENSRNOG00000059061 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:29796
UqcrbGeneProductENSRNOG00000032204 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7381
Uqcrc1GeneProductENSRNOG00000032134 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7384
Uqcrc2GeneProductENSRNOG00000036742 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7385
Uqcrfs1GeneProductENSRNOG00000018281 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7386
UqcrhGeneProductENSRNOG00000012550 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7388
UqcrqGeneProductENSRNOG00000048174 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:27089
e-MetaboliteC05359 (KEGG Compound)

Annotated Interactions

No annotated interactions
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