Folate metabolism (Bos taurus)

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45, 87, 94, 105, 141...210, 30359, 6145, 97, 253, 275, 30997197144, 21140146, 279841127, 188, 24995, 178167MicronutrientsGlycogenesisSelenium statusEnzymesProtein*InhibitionReactionStimulationNegative EffectLEGENDNecessary stimulationCleavageProtein with polymorphismMetabolitesis composed ofBiomarker forLipoprotein melabolismCofactor conversionProtein tyrosine nitrationProcess or metabolism involved in Se PathwaySelenoproteinsFrom intracellular part to the plasmaOther proteinsConversionCatalysisProstaglandins metabolismCofactorsTranscription factorBindingOverarching processLipid peroxidationIntracellularMethylation reactionsApoptosisNovo purine biosynthetic pathwayDNA oxidationPlasmaRELAPGE1NFKB2PGE2SLC46A1F2-IsoprostaneThromboxane A2CCL2F2-IsoprostaneThromboxane B2TP53FOLR1NFKB1FOLR2CCL2FOLR48-Isoprostaglandin F2aFOLR3PGF2aPGE1PGE2SLC19A1Thromboxane B2PGF2a8-Isoprostaglandin F2a225, 28993, 225225, 28911, 18, 105, 183, 188...93, 22522131322137, 82, 22531337296196242230, 29637196196196313313242MTRMTHFD2SHMT2DHFRMAT1AAHCYMTHFD1MTRR68, 213, 291, 3212725, 178301, 3211135, 72, 133178171, 178CBS291, 318NADP+NADP+NADP+NADP+NADP+NADP+NADP+NOSMPOMPOCAT97, 23123024, 120, 252, 30924, 120, 252, 309CysteineCysteinePLGF2SERPINE1PLGSERPINE1F7PLATF2F7PLAT123139, 176176, 326123123139, 176123176, 326123123GPX4H2O2Dihydrofolate5-Formyl-THFGAR5,10-Methylene-THFFGAR10-Formyl-THF5,10-Methenyl-THF(11S)-hydroxymethylene-THF(11R)-hydroxymethylene-THF95, 17817817817872, 17895, 178178721785-methyl-THFFolateFolate5-methyl-THF11, 34, 39, 72, 154...72, 21372ECSODECSODRFK79H2OGPX3GPX3CTH291Heme97, 231, 318THF72NADPHNADPHNADPHNADPHNADPHNADPHNADPHGPX6ManganeseManganeseFolic acidFolic acid68, 72, 10468, 72, 104GPX2GPX 1RNS40, 97MTHFSSHMT1MTHFRGART17868, 7295, 178178HomocysteineHomocysteine13927, 45, 52, 139, 213...SOD1Pyridoxal 5'-phosphatePyridoxal 5'-phosphate42, 116, 23042, 116L-ArginineSerineGlycineGlycine171, 178154171, 178171, 178FMNTAGSAA1HDL/APOA1SAA4APOBACTHDLoxLDLHDL-CVLDL-TAGSAA3ACTAPOA1HDLVLDLVLDLVLDL/APOBAPOA1SCARB1HDL-CLDLRCholesterolAPOBAPOA1VLDL-TAGHDL/SAAABCA1LDLSAA2LDLoxLDLCholesterolTAG211, 212181207, 21144, 144, 252, 266181207, 21118144, 144, 252, 26690, 18131, 23321139, 21139, 44, 144, 252, 2662112111812112113118139, 211207, 211207, 21118131, 23339, 44, 144, 252, 26621190, 181211294257181207, 211, 212212O2146FAD8-OHdGFADCob(I)alaminCob(II)alamin8-OHdGCob(I)alamin25716753, 301, 32153, 301, 321167321301, 321ADPADPMagnesiumChlorineChlorineMagnesiumS-nitrosohomocysteineCystathionine52SOD2Serine171, 178ATPZincZincNO2HNO2HOClNOO3NO24, 52, 120, 18824, 120TNFCSF1TNFIFNGIFNGD-dimerIFNGIL4INSFibrinIR-AIL1BFibrinCRPHbA1cHBBALBCSF1IL4IL2INSIL6FibrinogenHbA1cICAM1FibrinogenD-dimerHBA1ALBIL6IL1BIFNGIL2183, 285191, 21016, 45, 94, 268123, 32616, 34, 44, 230, 279...196191, 21016, 218, 32231794196148317141123, 3261098765, 12310931718, 45, 191, 236183, 285156, 26865, 12318, 23616, 8718384, 90, 26845, 14118331714884, 90, 268Riboflavin71O2 S-Adenosylhomocysteine S-Adenosylmethionine S-AdenosylmethionineMethionine S-AdenosylhomocysteineMethionine72, 15772, 213, 31972, 278, 32172, 15731911, 72, 278, 321ADPNitrotyrosineNitrotyrosineONOO/ONOOHTetrahydrobiopterin4040154ATPATPFructosamineGlucoseGlucoseFructosamine10984, 31784, 317109IronIron121121FLAD179, 163


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This pathway was inferred from Homo sapiens pathway WP176(79883) with a 82.0% conversion rate.

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History

View all...
CompareRevisionActionTimeUserComment
134297view06:15, 20 July 2024EgonwFixed a reference
120905view14:16, 29 January 2022EgonwReplaced an old HMDB identifier with the current one
120356view15:27, 28 November 2021EgonwFixed a PubMed ID
117520view11:08, 21 May 2021EweitzModified title
107053view14:14, 17 September 2019MaintBotChEBI identifier normalization
106009view11:53, 16 August 2019MaintBotHMDB identifier normalization
98246view14:20, 14 August 2018EgonwReplace a PubChem SID with a Wikidata ID (which has more links out).
96339view15:36, 8 March 2018MkutmonUpdated homology conversion
96338view15:35, 8 March 2018MkutmonOntology Term : 'folate metabolic pathway' added !
86818view16:41, 11 July 2016EgonwConnecting lines.
85065view11:31, 10 April 2016EgonwReplaced a Wikipedia ID with a ChEBI ID.
82706view08:57, 23 October 2015EgonwoxLDL has a separate identifier.
80891view15:30, 30 June 2015Mkutmonhomology conversion
74466view16:08, 24 April 2014EgonwFixed a PubMed ID.
72574view15:52, 23 November 2013EgonwReplaced an outdated HMDB identifier with the 3.5 one.
72367view09:46, 13 November 2013EgonwReplaced old PubChem data sources with their new equivalents.
72366view09:40, 13 November 2013EgonwFixed the type of two proteins.
71408view19:01, 17 October 2013MaintBotAutomated update of data sources
63348view22:21, 9 May 2013MaintBotUpdated to 2013 gpml schema
58813view23:18, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40522view19:29, 1 March 2011MaintBotRemoved redundant pathway information and comments
33765view00:04, 9 December 2009MaintBotAutomatic update of empty xrefs
33195view18:18, 5 November 2009KhanspersModified categories
32527view12:58, 17 August 2009MaintBotFixed text labels
32214view12:44, 15 August 2009MaintBotFixed text labels
31708view11:51, 14 August 2009MaintBotFixed group labels
31225view19:43, 13 August 2009MaintBotFixed text labels
30644view22:31, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
S-AdenosylhomocysteineMetaboliteHMDB00939 (HMDB)
S-AdenosylmethionineMetaboliteHMDB01185 (HMDB)
(11R)-hydroxymethylene-THFMetabolite(11R)-hydroxymethylenetetrahydrofolate
(11S)-hydroxymethylene-THFMetabolite(11S)-hydroxymethylenetetrahydrofolate
10-Formyl-THFMetaboliteHMDB00972 (HMDB) 10-formyltetrahydrofolate
5,10-Methenyl-THFMetaboliteHMDB01354 (HMDB) 5,10-Methenyltetrahydrofolic acid
5,10-Methylene-THFMetaboliteHMDB01533 (HMDB) 5,10-Methylenetetrahydrofolate
5-Formyl-THFMetaboliteHMDB01562 (HMDB) 5-Formyltetrahydrofolate
5-methyl-THFMetaboliteHMDB01396 (HMDB)
  • 5-methyltetrahydrofolate
  • Predominant food folate
8-Isoprostaglandin F2aMetaboliteHMDB05083 (HMDB)
8-OHdGMetaboliteHMDB03333 (HMDB) 8-Hydroxy-deoxyguanosine
ABCA1ProteinENSBTAG00000020661 (Ensembl)
  • ATP-binding cassette, sub-family A (ABC1), member 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:19
ACTProteinENSBTAG00000048094 (Ensembl)
  • alpha-1-antichymotrypsin
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:12
ADPMetaboliteHMDB01341 (HMDB) Adenosine diphosphate
AHCYProteinENSBTAG00000018101 (Ensembl)
  • EC 3.3.1.1
  • Adenosylhomocysteinase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:191
ALBProteinENSBTAG00000017121 (Ensembl)
  • albumin
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:213
APOA1ProteinENSBTAG00000002258 (Ensembl)
  • apolipoprotein A-I
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:335
APOBProteinENSBTAG00000008505 (Ensembl)
  • apolipoprotein B
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:338
ATPMetaboliteHMDB00538 (HMDB) Adenosine triphosphate
CATProteinENSBTAG00000020980 (Ensembl)
  • EC 1.11.1.6
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:847
CBSProteinENSBTAG00000000160 (Ensembl)
  • EC 4.2.1.22
  • cystathionine-beta-synthase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:875
CCL2GeneProductENSBTAG00000037811 (Ensembl)
  • Monocyte Chemotactic Protein 1
  • CCL2
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6347
CRPProteinENSBTAG00000013907 (Ensembl)
  • C-reactive protein, pentraxin-related
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1401
CSF1ProteinENSBTAG00000000283 (Ensembl)
  • colony stimulating factor 1 (macrophage)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1435
CTHProteinENSBTAG00000014791 (Ensembl)
  • EC 4.4.1.1
  • cystathionase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1491
ChlorineMetaboliteHMDB00492 (HMDB)
CholesterolMetaboliteHMDB00067 (HMDB)
Cob(I)alaminMetaboliteHMDB02174 (HMDB) Reduced cobalamin
Cob(II)alaminMetaboliteHMDB02174 (HMDB) oxidized cobalamin
CystathionineMetaboliteHMDB00099 (HMDB)
CysteineMetaboliteHMDB00574 (HMDB)
D-dimerProteinhttp://en.wikipedia.org/wiki/Fibrin_degradation_product
DHFRProteinENSBTAG00000007681 (Ensembl)
  • EC 1.5.1.3
  • Dihydrofolate reductase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1719
DihydrofolateMetaboliteHMDB01056 (HMDB)
ECSODProteinENSBTAG00000013980 (Ensembl)
  • EC 1.15.1.1
  • superoxide dismutase 3, extracellular
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6649
F2-IsoprostaneMetabolite53788444 (PubChem-substance)
F2ProteinENSBTAG00000007148 (Ensembl)
  • EC 3.4.21.5
  • coagulation factor II (thrombin)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2147
F7ProteinENSBTAG00000007411 (Ensembl)
  • EC 3.4.21.21
  • coagulation factor VII (serum prothrombin conversion accelerator)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2155
FADMetaboliteHMDB01248 (HMDB) Flavin adenine dinucleotide
FGARMetabolite18272 (ChEBI) formylglycinamide ribonucleotide
FLAD1ProteinENSBTAG00000000186 (Ensembl)
  • EC 2.7.7.2
  • FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:80308
FMNMetaboliteHMDB01520 (HMDB) Flavin Mononucleotide
FOLR1GeneProductENSBTAG00000021007 (Ensembl)
  • folate receptor 1 (adult)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2348
FOLR2GeneProductENSBTAG00000027684 (Ensembl)
  • folate receptor 2 (fetal)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2350
FOLR3GeneProductfolate receptor 3 (gamma)
FOLR4GeneProductfolate receptor 4 (delta) homolog (mouse)
FibrinMetabolite439199 (PubChem-compound)
FibrinogenProtein
FolateMetabolite37445 (ChEBI) Generic term used to denote both naturally occurring folate in foods (food folate) and the synthetic form of the vitamin (folic acid).
Folic acidMetaboliteHMDB00121 (HMDB) Synthetic folate
FructosamineMetaboliteHMDB02030 (HMDB)
GARMetaboliteHMDB02022 (HMDB) glycinamide ribonucleotide
GARTProteinENSBTAG00000009188 (Ensembl)
  • EC 2.1.2.2
  • phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2618
GPX 1Protein
  • EC 1.11.1.9
  • Selenoprotein-glutathione peroxidase 1
GPX2ProteinENSBTAG00000048112 (Ensembl)
  • EC 1.11.1.9
  • Selenoprotein-glutathione peroxidase 2
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2877
GPX3ProteinENSBTAG00000043553 (Ensembl)
  • EC 1.11.1.9
  • Selenoprotein-glutathione peroxidase 3
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2878
GPX4ProteinENSBTAG00000046926 (Ensembl)
  • EC 1.11.1.12
  • Selenoprotein-glutathione peroxidase 4
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2879
GPX6ProteinENSBTAG00000012023 (Ensembl)
  • EC 1.11.1.9
  • Selenoprotein-glutathione peroxidase 6
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:257202
GlucoseMetaboliteHMDB00122 (HMDB)
GlycineMetaboliteHMDB00123 (HMDB)
H2O2MetaboliteHMDB03125 (HMDB) Hydrogen peroxide
H2OMetaboliteHMDB02111 (HMDB) Glutathione disulfide
HBA1Protein
  • hemoglobin, alpha 1
  • HomologyConvert: Multiple homologues found: En:ENSBTAG00000026417;En:ENSBTAG00000026417;
HBBProteinENSBTAG00000038748 (Ensembl)
  • hemoglobin, beta
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3043
HDL-CMetabolite47775 (ChEBI)
  • high-density lipoprotein cholesterol
  • Cholesterol transport
HDL/APOA1Metabolite39025 (ChEBI)
  • high-density lipoprotein
  • ApoA-I is present on the majority of HDL particles and constitutes aprox 70% of the apolipoprotein content of HDL particles
HDL/SAAMetabolite39025 (ChEBI)
  • high-density lipoprotein
  • SAA circulates in plasma as a constituent of high density lipoproteins (HDL).
HDLMetabolite39025 (ChEBI) high-density lipoprotein
HNO2Metabolite25567 (ChEBI) Nitrous acid
HOClMetaboliteHMDB01050 (HMDB) Hypochlorite
HbA1cProtein
  • Glycated hemoglobin
  • http://en.wikipedia.org/wiki/Glycated_hemoglobin
HemeMetaboliteHMDB03178 (HMDB)
HomocysteineMetaboliteHMDB00742 (HMDB)
ICAM1ProteinENSBTAG00000010303 (Ensembl)
  • soluble intercellular adhesion molecule 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3383
IFNGProteinENSBTAG00000012529 (Ensembl)
  • interferon, gamma
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3458
IL1BProteinENSBTAG00000001321 (Ensembl)
  • interleukin 1, beta
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3553
IL2ProteinENSBTAG00000020883 (Ensembl)
  • interleukin 2
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3558
IL4ProteinENSBTAG00000015957 (Ensembl)
  • interleukin 4
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3565
IL6ProteinENSBTAG00000014921 (Ensembl)
  • interleukin 6 (interferon, beta 2)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3569
INSProteinInsulin
IR-AProteinENSBTAG00000012687 (Ensembl)
  • Insulin receptor
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3643
IronMetaboliteHMDB00692 (HMDB)
L-ArginineMetaboliteHMDB00517 (HMDB)
LDLMetabolite39026 (ChEBI) low-density lipoprotein
LDLRProteinENSBTAG00000012314 (Ensembl)
  • low density lipoprotein receptor
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3949
MAT1AProteinENSBTAG00000005963 (Ensembl)
  • EC 2.5.1.6
  • Methionine adenosyltransferase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4143
MPOProteinENSBTAG00000011616 (Ensembl)
  • EC 1.11.1.7
  • Myeloperoxidase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4353
MTHFD1ProteinENSBTAG00000009641 (Ensembl)
  • EC 1.5.1.5
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4522
MTHFD2ProteinENSBTAG00000004881 (Ensembl)
  • EC 3.5.4.9
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10797
MTHFRProteinENSBTAG00000020698 (Ensembl)
  • EC 1.5.1.20
  • 5,10-methylenetetrahydrofolate reductase
  • Homozygous of (MTHFR) 677C-T variant may have enzyme activities up to 50% lower than those without the polymorphism increasing the risk of hyperhomocysteinemia
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4524
MTHFSProtein
  • EC 6.3.3.2
  • 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
  • HomologyConvert: Multiple homologues found: En:ENSBTAG00000020023;En:ENSBTAG00000020023;
MTRProteinENSBTAG00000012251 (Ensembl)
  • EC 2.1.1.13
  • 5-methyltetrahydrofolate-homocysteine methyltransferase
  • Also known as MS
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4548
MTRRProteinENSBTAG00000009401 (Ensembl)
  • EC 1.16.1.8
  • 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4552
MagnesiumMetaboliteHMDB00547 (HMDB)
ManganeseMetaboliteHMDB01333 (HMDB)
MethionineMetaboliteHMDB00696 (HMDB)
NADP+MetaboliteHMDB00217 (HMDB) Nicotinamide adenine dinucleotide phosphate-Oxidized
NADPHMetaboliteHMDB00221 (HMDB) Nicotinamide adenine dinucleotide phosphate-Reduced
NFKB1GeneProductENSBTAG00000020270 (Ensembl)
  • nuclear factor NF-kappa-B p50 subunit
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4790
NFKB2GeneProductENSBTAG00000006017 (Ensembl)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4791
NO2Metabolite33101 (ChEBI) Nitrogen dioxide
NOMetaboliteHMDB03378 (HMDB) Nitric oxide
NOSProteinNitric oxide synthase
NitrotyrosineMetaboliteHMDB01904 (HMDB)
O2MetaboliteHMDB01377 (HMDB)
O2MetaboliteHMDB02168 (HMDB) Superoxide
O3Metabolite25812 (ChEBI) ozone
ONOO/ONOOHMetaboliteHMDB02179 (HMDB) Peroxynitrite
PGE1MetaboliteHMDB01442 (HMDB) Prostaglandin E1
PGE2MetaboliteHMDB01220 (HMDB) Prostaglandin E2
PGF2aMetaboliteHMDB01139 (HMDB) Prostaglandin F2a
PLATProteinENSBTAG00000001244 (Ensembl)
  • EC 3.4.21.68
  • plasminogen activator, tissue
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5327
PLGProteinENSBTAG00000001271 (Ensembl)
  • EC 3.4.21.7
  • Plasminogen
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5340
Pyridoxal 5'-phosphateMetaboliteHMDB01491 (HMDB)
RELAGeneProductENSBTAG00000013895 (Ensembl)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5970
RFKProteinENSBTAG00000019345 (Ensembl)
  • EC 2.7.1.26
  • riboflavin kinase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55312
RNSMetaboliteCHEBI:62764 (ChEBI)
  • reactive nitrogen species
  • http://en.wikipedia.org/wiki/Reactive_nitrogen_species
RiboflavinMetaboliteHMDB00244 (HMDB)
S-nitrosohomocysteineMetabolite3035701 (PubChem-compound)
SAA1Proteinserum amyloid A1
SAA2Proteinserum amyloid A2
SAA3Proteinserum amyloid A3 pseudogene
SAA4ProteinENSBTAG00000002963 (Ensembl)
  • serum amyloid A4, constitutive
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6291
SCARB1ProteinENSBTAG00000014269 (Ensembl)
  • scavenger receptor class B, member 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:949
SERPINE1ProteinENSBTAG00000014465 (Ensembl)
  • Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054
SHMT1ProteinENSBTAG00000017094 (Ensembl)
  • EC 2.1.2.1
  • Serine hydroxymethyltransferase 1 (soluble)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6470
SHMT2ProteinENSBTAG00000031500 (Ensembl)
  • EC 2.1.2.1
  • Serine hydroxymethyltransferase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6472
SLC19A1GeneProductENSBTAG00000024162 (Ensembl)
  • solute carrier family 19 (folate transporter), member 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6573
SLC46A1GeneProductENSBTAG00000002817 (Ensembl)
  • solute carrier family 46 (folate transporter), member 1
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:113235
SOD1ProteinENSBTAG00000018854 (Ensembl)
  • EC 1.15.1.1
  • superoxide dismutase 1, soluble
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6647
SOD2ProteinENSBTAG00000006523 (Ensembl)
  • EC 1.15.1.1
  • superoxide dismutase 2, mitochondrial
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6648
SerineMetaboliteHMDB00187 (HMDB)
TAGMetabolite17855 (ChEBI)
  • Triglyceride
  • Triacylglycerol
THFMetaboliteHMDB01846 (HMDB) Tetrahydrofolic acid
TNFProteinENSBTAG00000025471 (Ensembl)
  • tumor necrosis factor (TNF superfamily, member 2)
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7124
TP53GeneProductENSBTAG00000001069 (Ensembl)
  • tumor protein p53
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7157
TetrahydrobiopterinMetaboliteHMDB00027 (HMDB) H4B
Thromboxane A2MetaboliteHMDB01452 (HMDB)
Thromboxane B2MetaboliteHMDB03252 (HMDB)
VLDL-TAGMetabolite47776 (ChEBI)
  • very-low-density lipoprotein-triglyceride
  • Triglyceride transport
VLDL/APOBMetabolite39027 (ChEBI)
  • very-low-density lipoprotein
  • The VLDL is produced in the liver, contains one molecule of apoB100
VLDLMetabolite39027 (ChEBI) very-low-density lipoprotein
ZincMetaboliteHMDB01303 (HMDB)
oxLDLMetaboliteCHEBI:60151 (ChEBI) oxidized low-density lipoprotein

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1075"
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