Regulation of sister chromatid separation at the metaphase-anaphase transition (Homo sapiens)

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1Spindle checkpoint ONUbiquitin-mediateddegradationChromosomes attach to spindleChromosomes alignSMC1ACDC20ESPL1MAD1L1MAD2L1PBUB1BUB1BBUB3CENPEANAPC2ANAPC11PTTG1ESPL1PTTG1UbPrometaphaseMetaphaseAnaphaseSeparation of sister chromatidsSMC3RAD21STAG1ESPL1PChromosomes separateSpindle checkpoint OFF


Description

No description

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Ontology Terms

 

Bibliography

  1. Pino MS, Chung DC; ''The chromosomal instability pathway in colon cancer.''; Gastroenterology, 2010 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
127399view20:40, 29 September 2023Khansperscorrected gene id
127395view19:46, 29 September 2023Khanspersremoved phospho site
127250view17:38, 28 August 2023KhanspersAdded literature reference and updated description
106495view21:43, 4 September 2019KhanspersModified description
105506view05:58, 8 August 2019KhanspersModified description
96623view17:27, 23 March 2018KhanspersModified description
96621view17:23, 23 March 2018KhanspersOntology Term : 'cell cycle pathway, mitotic' added !
96620view17:20, 23 March 2018KhanspersModified description
96619view17:19, 23 March 2018KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ANAPC11GeneProductENSG00000141552 (Ensembl)
ANAPC2GeneProductENSG00000176248 (Ensembl)
BUB1BGeneProductENSG00000156970 (Ensembl)
BUB1GeneProductENSG00000169679 (Ensembl)
BUB3GeneProductENSG00000154473 (Ensembl)
CDC20GeneProductENSG00000117399 (Ensembl)
CENPEGeneProductENSG00000138778 (Ensembl)
ESPL1GeneProductENSG00000135476 (Ensembl)
MAD1L1GeneProductENSG00000002822 (Ensembl)
MAD2L1GeneProductENSG00000164109 (Ensembl)
PTTG1GeneProductENSG00000164611 (Ensembl)
RAD21GeneProductENSG00000164754 (Ensembl)
SMC1AGeneProductENSG00000072501 (Ensembl)
SMC3GeneProductENSG00000108055 (Ensembl)
STAG1GeneProductENSG00000118007 (Ensembl)

Annotated Interactions

No annotated interactions

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