From WikiPathways
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Benzoate degradation via hydroxylation 6-Hydroxykynurenate 4-(2-Amino-5-hydroxyphenyl) -2,4-dioxobutanoate 5-Hydroxykynurenamine N-Acetylindoxyl 2,3-Dihydroxyindole 2-Oxoglutarate Oxaloacetate 5-(2'-Formylethyl)-4,6-dihydroxypicolinate 5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin 7,8-Dihydroxykynurenate 7,8-Dihydro-7,8-dihydroxykynurenate Kynurenate 4-(2-Aminophenyl)-2,4-dioxobutanoate 2-Formylaminobenzaldehyde 3-Indoleglycolaldehyde 5-Hydroxyindolepyruvate C01144 2-Oxoadipate 2-Aminomuconate 2-Aminomuconate Quinolinate 2-Amino-3-carboxymuconate 3-Hydroxyanthranilate 4,8-Dihydroxyquinoline 3-Hydroxykynurenamine 3-Hydroxy- L-kynurenine Isophenoxazine Cinnavalininate L-Tryptophanyl-tRNA 3-(2-Aminoethyl) -1H-indol-5-ol 5-Hydroxyindoleacetate Formyl-5-hydroxykynurenamine Formyl-N-acetyl-5- methoxykynurenamine Indolepyruvate Indolelactate 3-Methylindolepyruvate 6-Hydroxyindolelactate Indole-3-acetate Indole-3-acetaldehyde 5-Methoxyindoleacetate 5-Hydroxyindoleacetylglycine Indole-3-ethanol 3-Methyldioxyindole 2-Formamino benzoylacetate Indole-3-acetaldoxime Glucobrassicin 3-Methoxyanthranilate 8-Methoxykynurenate Anthranilate Anthranilate Formylanthranilate (Z)-5-Oxohex-2-enedioate 2.6.1.27 IDO1 ASMT HRMT1L2 AANAT IDO1 MAOB DDC 2.6.1.27 DDC IDO1 1.13.11.17 1.7.3.2 1.14.16.- 3.5.1.49 3.5.1.9 1.13.11.23 1.14.16.3 ACAT1 ECHS1 OGDH 1.2.1.32 ACMSD HAAO KYNU 1.14.13.9 KYNU KYNU TDO2 4.1.99.1 TPH1 WARS 1.13.99.3 CAT AADAT AADAT 1.10.3.4 MAOB 1.13.11.- 1.5.1.- DHCR24 1.13.11.10 1.3.1.18 1.14.99.2 1.13.12.3 DDC MAOB 4.1.1.43 1.2.3.7 2.1.1.47 1.1.1.110 CYP7B1 AFMID AOX1 1.2.1.- HRMT1L2 HRMT1L2 MAOB 4.2.1.84 3.5.1.4 3.5.5.1 3.2.1.147 1.1.1.190 1.1.1.191 ABP1 2.1.1.49 INMT 3.5.99.5 4.1.1.- ASMT 5-Hydroxykynurenine N-Acetylisatin Acetyl-CoA L-Kynurenine Formylkynurenine Indole Indole-3-acetamide L-Tryptophan 2-Aminophenol 5-Methoxytryptamine N-Acetylserotonin 6-Hydroxymelatonin Tryptamine 3-Indoleacetonitrile 4,6-Dihydroxyquinoline 5-Hydroxy-L-tryptophan 5-Hydroxy-N-formylkynurenine 5-Hydroxyindoleacetaldehyde N-Methylserotonin Melatonin N-Methyltryptamine Xanthurenic acid 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate Acetoacetyl-CoA Crotonoyl-CoA Glutaryl-CoA 5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate Benzoate degradation via hydroxylation Glycolysis/Gluconeogenesis Nicotinate and nicotinamide metabolism Phenylalanine, Tyrosine and Tryptophan metabolism ALDH3A2 ALDH1A2 ALDH1A1 Aldh1a4 ALDH2 ALDH9A1 CYP2J2 CYP1A1 CYP1A2 CYP2A13 Cyp2a1 Cyp2a2 Cyp2c12 Cyp2d2 CYP2E1 CYP19A1 CYP1B1 CYP3A4 CYP2C18 Cyp2b15 Cyp2c39 CYP2F1 CYP4F12 Group object MDM2 UBR5 MDM2 MDM2 UBE3A UBE3A RNF25 RNF25 Group object ALDH3A2 ALDH1A2 ALDH1A1 ALDH2 Aldh1a4 ALDH9A1 Group object GCDH GCDH Group object HSD17B10 HADH Group object 1.4.3.2 2.6.1.27 Group object Name: Tryptophan metabolism License: CC BY 2.0 Last Modified: 10/16/2013 Organism: Bos taurus
Description
Tryptophan (symbol Trp or W; encoded by the codon UGG) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a non-polar aromatic amino acid. Many animals (including humans) cannot synthesize tryptophan: they need to obtain it through their diet, making it an essential amino acid. Tryptophan is among the less common amino acids found in proteins, but it plays important structural or functional roles whenever it occurs. For instance, tryptophan and tyrosine residues play special roles in "anchoring" membrane proteins within the cell membrane. In addition, tryptophan functions as a biochemical precursor.
Comments
Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
Ontology Terms
Bibliography
No bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions