Ciliary landscape (Homo sapiens)

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1complex 53MAK/ICK/KIAA0556ANKS/NEKcomplex FOX/RFXcomplex 31IFT-AHSF1/HSPA1L/MAPRE2U5-snRNPexocyst-1BBSomeNEFNOTcomplex 5GIDcomplex 21ARL/NPHP/UNC119ExosomeBasal bodyAxonemecomplex 7complex 5complex 28complex 16complex 26complex 9TRAPPMCMNucleuscomplex 49complex 15U4/U6-snRNPcomplex 12Dynein-1complex 29complex 19IQ/CALM1complex 39complex 47IFT-B1complex 3ProteasomeTUBG/NMECOP9 signalosomecomplex 44Cell membraneCiliumTransition zoneRPGRTFAP2CCOPS1NDUFA5RBM14UBE2D2NME8LCA5APCDCAF7CDR2SSNA1DVL3DGKEMCM8MFAP1NUDCIFT46ARHGDIARABEP2ARL8BTMED1RAB3IL1ECHS1SNAP29TFAP2ACDH23ARFGAP3RB1ERFTFAP2BNUP88CTSANINLCNOT10RHBDD2H3F3AMCM3COPS3EFTUD2IFT52HDAC2IFT20SNRPB2TNKS1BP1NUP133TSSC1COPS7ACEP170RQCD1USH1CCLTIFT27GDI1DYNLL1COPS6YAP1MCM6CEP97POM121TFAP2EIFT140MCM5AIMP1CTNNB1MKS1MCM2NFKB1COPS4MCM9RAB14ACSL3RAB21CCDC40CNOT1TFAP2DCOPS8CBSHDAC1CTBP2LSM4MCM7IFT81DNPEPMCM10IFT43COPS7BCAMK2AGLAEHBP1COPS2IFT57CD2BP2MCM4IFT74DYNLL2RAB2AUQCC1MSH2DCAF11SPATA7EXOSC9COPS5IFT122CNOT6LNDUFA9WNK1WEE1CREBBPCytosolcomplex 46exocyst-2IFT-BIFT88IFT80IFT172IFT-B2DynactinDynein-2


Description

Ciliary landscape pathway - according to Boldt et al. 2016

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Quality Tags

Ontology Terms

 

Bibliography

  1. Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R; ''An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.''; Nat Commun, 2016 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134800view02:56, 27 July 2024EweitzOntology Term : 'Meckel syndrome' added !
134799view02:55, 27 July 2024EweitzOntology Term : 'Bardet-Biedl syndrome' added !
134798view02:55, 27 July 2024EweitzOntology Term : 'Usher syndrome' added !
134797view02:55, 27 July 2024EweitzOntology Term : 'polycystic kidney disease' added !
102218view20:44, 11 December 2018Khanspersfixed unconnected interactions
98719view14:32, 1 October 2018FehrhartProteasome
98718view14:20, 1 October 2018FehrhartIQ/GAP
98717view14:07, 1 October 2018FehrhartGID
98716view13:45, 1 October 2018FehrhartNEF
98715view13:21, 1 October 2018Fehrhartadded BBSome and dynein complexes
98714view12:52, 1 October 2018Fehrhartadded complexes IFTB1 and B2
98599view14:12, 20 September 2018FehrhartModified description
98598view14:06, 20 September 2018FehrhartOntology Term : 'ciliopathy' added !
98597view14:05, 20 September 2018FehrhartOntology Term : 'transport pathway' added !
98596view13:56, 20 September 2018FehrhartNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACSL3GeneProductENSG00000123983 (Ensembl)
AIMP1GeneProductENSG00000164022 (Ensembl)
APCGeneProductENSG00000134982 (Ensembl)
ARFGAP3GeneProduct26286 (Entrez Gene)
ARHGDIAGeneProductENSG00000141522 (Ensembl)
ARL8BGeneProductENSG00000134108 (Ensembl)
CAMK2AGeneProductENSG00000070808 (Ensembl)
CBSGeneProductENSG00000160200 (Ensembl)
CCDC40GeneProductENSG00000141519 (Ensembl)
CD2BP2GeneProductENSG00000169217 (Ensembl)
CDH23GeneProductENSG00000107736 (Ensembl)
CDR2GeneProductENSG00000140743 (Ensembl)
CEP170GeneProductENSG00000143702 (Ensembl)
CEP97GeneProductENSG00000182504 (Ensembl)
CLTGeneProductno idea what that should be
CNOT10GeneProductENSG00000182973 (Ensembl)
CNOT1GeneProductENSG00000125107 (Ensembl)
CNOT6LGeneProductENSG00000138767 (Ensembl)
COPS1GeneProductno annotation found yet
COPS2GeneProductENSG00000166200 (Ensembl)
COPS3GeneProductENSG00000141030 (Ensembl)
COPS4GeneProductENSG00000138663 (Ensembl)
COPS5GeneProductCOPS5 (HGNC)
COPS6GeneProductENSG00000168090 (Ensembl)
COPS7AGeneProductENSG00000111652 (Ensembl)
COPS7BGeneProductENSG00000144524 (Ensembl)
COPS8GeneProductENSG00000198612 (Ensembl)
CREBBPGeneProductENSG00000005339 (Ensembl)
CTBP2GeneProductENSG00000175029 (Ensembl)
CTNNB1GeneProductENSG00000168036 (Ensembl)
CTSAGeneProductENSG00000064601 (Ensembl)
DCAF11GeneProductENSG00000100897 (Ensembl)
DCAF7GeneProductENSG00000136485 (Ensembl)
DGKEGeneProductENSG00000153933 (Ensembl)
DNPEPGeneProductENSG00000123992 (Ensembl)
DVL3GeneProductENSG00000161202 (Ensembl)
DYNLL1GeneProductENSG00000088986 (Ensembl)
DYNLL2GeneProductENSG00000264364 (Ensembl)
ECHS1GeneProductENSG00000127884 (Ensembl)
EFTUD2GeneProductENSG00000108883 (Ensembl)
EHBP1GeneProductENSG00000115504 (Ensembl)
ERFGeneProductENSG00000105722 (Ensembl)
EXOSC9GeneProductENSG00000123737 (Ensembl)
GDI1GeneProductENSG00000203879 (Ensembl)
GLAGeneProductENSG00000102393 (Ensembl)
H3F3AGeneProductENSG00000163041 (Ensembl)
HDAC1GeneProductENSG00000116478 (Ensembl)
HDAC2GeneProductENSG00000196591 (Ensembl)
IFT122GeneProductENSG00000163913 (Ensembl)
IFT140GeneProductENSG00000187535 (Ensembl)
IFT172GeneProductENSG00000138002 (Ensembl)
IFT20GeneProductENSG00000109083 (Ensembl)
IFT27GeneProductENSG00000100360 (Ensembl)
IFT43GeneProductENSG00000119650 (Ensembl)
IFT46GeneProductENSG00000118096 (Ensembl)
IFT52GeneProductENSG00000101052 (Ensembl)
IFT57GeneProductENSG00000114446 (Ensembl)
IFT74GeneProductENSG00000096872 (Ensembl)
IFT80GeneProductENSG00000068885 (Ensembl)
IFT81GeneProductENSG00000122970 (Ensembl)
IFT88GeneProductENSG00000032742 (Ensembl)
LCA5GeneProductENSG00000135338 (Ensembl)
LSM4GeneProductENSG00000130520 (Ensembl)
MCM10GeneProductENSG00000065328 (Ensembl)
MCM2GeneProductENSG00000073111 (Ensembl)
MCM3GeneProductENSG00000112118 (Ensembl)
MCM4GeneProductENSG00000104738 (Ensembl)
MCM5GeneProductENSG00000100297 (Ensembl)
MCM6GeneProductENSG00000076003 (Ensembl)
MCM7GeneProductENSG00000166508 (Ensembl)
MCM8GeneProductENSG00000125885 (Ensembl)
MCM9GeneProductENSG00000111877 (Ensembl)
MFAP1GeneProductENSG00000140259 (Ensembl)
MKS1GeneProductENSG00000011143 (Ensembl)
MSH2GeneProductENSG00000095002 (Ensembl)
NDUFA5GeneProductENSG00000128609 (Ensembl)
NDUFA9GeneProductENSG00000139180 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
NINLGeneProductENSG00000101004 (Ensembl)
NME8GeneProductENSG00000086288 (Ensembl)
NUDCGeneProductENSG00000090273 (Ensembl)
NUP133GeneProductENSG00000069248 (Ensembl)
NUP88GeneProductENSG00000108559 (Ensembl)
POM121GeneProductENSG00000196313 (Ensembl)
RAB14GeneProductENSG00000119396 (Ensembl)
RAB21GeneProductENSG00000080371 (Ensembl)
RAB2AGeneProductENSG00000104388 (Ensembl)
RAB3IL1GeneProductENSG00000167994 (Ensembl)
RABEP2GeneProductENSG00000177548 (Ensembl)
RB1GeneProductENSG00000139687 (Ensembl)
RBM14GeneProductENSG00000239306 (Ensembl)
RHBDD2GeneProductENSG00000005486 (Ensembl)
RPGRGeneProductENSG00000156313 (Ensembl)
RQCD1ProteinD5MQE1 (Uniprot-TrEMBL)
SNAP29GeneProductENSG00000099940 (Ensembl)
SNRPB2GeneProductENSG00000125870 (Ensembl)
SPATA7GeneProductENSG00000042317 (Ensembl)
SSNA1GeneProductENSG00000176101 (Ensembl)
TFAP2AGeneProductENSG00000137203 (Ensembl)
TFAP2BGeneProductENSG00000008196 (Ensembl)
TFAP2CGeneProductENSG00000087510 (Ensembl)
TFAP2DGeneProductENSG00000008197 (Ensembl)
TFAP2EGeneProductENSG00000116819 (Ensembl)
TMED1GeneProductENSG00000099203 (Ensembl)
TNKS1BP1GeneProductENSG00000149115 (Ensembl)
TSSC1GeneProductENSG00000032389 (Ensembl)
UBE2D2GeneProductENSG00000131508 (Ensembl)
UQCC1GeneProductENSG00000101019 (Ensembl)
USH1CGeneProductENSG00000006611 (Ensembl)
WEE1GeneProductENSG00000166483 (Ensembl)
WNK1GeneProductENSG00000060237 (Ensembl)
YAP1GeneProductENSG00000137693 (Ensembl)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP4352"
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