Acetylcholine synthesis (Danio rerio)
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Description
Acetylcholine is an important neurotransmitter. It can be rapidly released in the synaptic cleft upon activation of the neuron. In the synaptic cleft the compound is degraded rapidly into choline and acetate, this is essential for proper neuronal functioning. Choline and Acetate are taken up into the cytosol and recycled for the next activation.
Quality Tags
Ontology Terms
Bibliography
- Blusztajn JK, Wurtman RJ; ''Choline and cholinergic neurons.''; Science, 1983 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Acetate | Metabolite | CHEBI:30089 (ChEBI) | |
Acetyl-CoA | Metabolite | CHEBI:57288 (ChEBI) | |
Acetylcholine | Metabolite | CHEBI:15355 (ChEBI) | |
Choline | Metabolite | CHEBI:15354 (ChEBI) | |
Choline | Metabolite | CHEBI:15354 (ChEBI) | |
Cytidine diphosphate choline | Metabolite | CHEBI:16436 (ChEBI) | |
Glycerophosphocholine | Metabolite | CHEBI:36313 (ChEBI) | |
Phosphorylcholine | Metabolite | CHEBI:18132 (ChEBI) | |
Posphatidylcholines | Metabolite | CHEBI:49183 (ChEBI) | |
Posphatidylethanolamines | Metabolite | CHEBI:16038 (ChEBI) | |
ache | GeneProduct | 114549 (Entrez Gene) | |
chat | GeneProduct | 100170938 (Entrez Gene) | |
chka | GeneProduct | ENSDARG00000041078 (Ensembl) | |
pcyt1aa | GeneProduct | 550327 (Entrez Gene) | |
pdha1a | GeneProduct | 406702 (Entrez Gene) | |
pdha2 | GeneProduct | ||
pemt | GeneProduct | 393127 (Entrez Gene) |
Annotated Interactions
No annotated interactions