Oxidation by cytochrome P450 (Bos taurus)
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Cytochrome P450 genes
CYP11A1
Fe2+
activated O2
CYP3A5
CYP4Z1
CYP2A7
CYP2F1
CYP7A1
CYP26C1
CYP7B1
Substrate-OH
CYP
CYP4F12
CYP2W1
O2
CYP4F22
CYP26B1
CYB5R1
NADH
CYP2A6
CYP2A13
CYP51A1
H2O
Substrate
CYP2S1
CYB5B
CYB5R4
Fe3+
CYP2J2
CYP1B1
Fe3+
CYP2C8
NAD+
CYP46A1
CYP39A1
O2
CYP21A2
Fe2+
CYB5A
CYP4V2
CYP2G1P
CYP3A4
Substrate
CYP2C18
CYP20A1
CYP27C1
CYP
CYP3A43
Substrate
CYP51A1
CYP4F2
CYP4A22
CYP11B2
CYP2R1
CYP17A1
CYP
CYP4F3
CYP2C19
CYP27B1
CYP4B1
Substrate
Fe3+
CYP19A1
CYP11B1
CYP2E1
CYP4F11
CYP4X1
Fe2+
Fe2+
Fe3+
NADPH
CYP27A1
NADP+
CYB5R2
Substrate
CYP2U1
CYB5R3
CYP1A1
CYB5B
CYP4F3
CYP3A7
CYB5B
CYB5A
POR
CYP4A11
CYP8B1
CYB5A
CYP2B6
CYP
CYP2C9
CYP1A2
CYP
MGC127055
CYP24A1
CYP26A1
Description
Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48.
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP43(79993)
with a 95.0% conversion rate.
Try the New WikiPathways
View approved pathways at
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.
Quality Tags
Ontology Terms
Saving...
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Bibliography
Niesink, R.J.M, Vries, de, J., Hollinger, M.A.; ''Toxicology; Principles and Applications''; , 1996
History
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Compare
Revision
Action
Time
User
Comment
125262
view
12:14, 31 January 2023
Larsgw
Add ISBN to publication
117586
view
11:24, 21 May 2021
Eweitz
Modified title
113856
view
06:17, 2 December 2020
Egonw
Added missing DataNode types
107055
view
14:14, 17 September 2019
MaintBot
ChEBI identifier normalization
105991
view
11:51, 16 August 2019
MaintBot
HMDB identifier normalization
102463
view
05:50, 24 December 2018
Egonw
Fixed a data source.
101941
view
06:26, 19 November 2018
Egonw
Replaced Wikipedia with Wikidata identifiers.
80775
view
15:25, 30 June 2015
Mkutmon
homology conversion
73517
view
23:31, 29 January 2014
Khanspers
Modified title
72372
view
09:55, 13 November 2013
Egonw
Fixed the PubChem-compound database name.
71405
view
19:01, 17 October 2013
MaintBot
Automated update of data sources
70162
view
00:26, 13 July 2013
AlexanderPico
Modified title
63345
view
22:21, 9 May 2013
MaintBot
Updated to 2013 gpml schema
58812
view
23:18, 20 February 2013
MaintBot
Updated Ensembl and UniProt data source
40519
view
19:29, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33762
view
00:03, 9 December 2009
MaintBot
Automatic update of empty xrefs
31710
view
11:52, 14 August 2009
MaintBot
Fixed group labels
30646
view
22:32, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CYB5A
GeneProduct
ENSBTAG00000012012 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166347
CYB5B
GeneProduct
ENSBTAG00000002412 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000103018
CYB5R1
GeneProduct
ENSBTAG00000019927 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000159348
CYB5R2
GeneProduct
ENSBTAG00000016142 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166394
CYB5R3
GeneProduct
ENSBTAG00000016516 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000100243
CYB5R4
GeneProduct
ENSBTAG00000013591 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000065615
CYP11A1
GeneProduct
ENSBTAG00000006934 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140459
CYP11B1
GeneProduct
ENSBTAG00000004596 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000160882
CYP11B2
GeneProduct
ENSBTAG00000004596 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000179142
CYP17A1
GeneProduct
ENSBTAG00000014335 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148795
CYP19A1
GeneProduct
ENSBTAG00000014890 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000137869
CYP1A1
GeneProduct
ENSBTAG00000001021 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140465
CYP1A2
GeneProduct
ENSBTAG00000000085 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505
CYP1B1
GeneProduct
ENSBTAG00000010531 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
CYP20A1
GeneProduct
ENSBTAG00000000851 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000119004
CYP21A2
GeneProduct
CYP24A1
GeneProduct
ENSBTAG00000002765 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000019186
CYP26A1
GeneProduct
ENSBTAG00000021118 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000095596
CYP26B1
GeneProduct
ENSBTAG00000012212 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000003137
CYP26C1
GeneProduct
ENSBTAG00000039973 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000187553
CYP27A1
GeneProduct
ENSBTAG00000013489 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000135929
CYP27B1
GeneProduct
ENSBTAG00000016906 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111012
CYP27C1
GeneProduct
ENSBTAG00000038275 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186684
CYP2A13
GeneProduct
ENSBTAG00000047815 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197838
CYP2A6
GeneProduct
ENSBTAG00000047815 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000255974
CYP2A7
GeneProduct
ENSBTAG00000047815 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000198077
CYP2B6
GeneProduct
ENSBTAG00000003871 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197408
CYP2C18
GeneProduct
ENSBTAG00000020375 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108242
CYP2C19
GeneProduct
ENSBTAG00000020375 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000165841
CYP2C8
GeneProduct
ENSBTAG00000020375 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138115
CYP2C9
GeneProduct
ENSBTAG00000020375 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138109
CYP2E1
GeneProduct
ENSBTAG00000018365 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000130649
CYP2F1
GeneProduct
ENSBTAG00000046805 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197446
CYP2G1P
GeneProduct
CYP2J2
GeneProduct
ENSBTAG00000013693 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000134716
CYP2R1
GeneProduct
ENSBTAG00000010419 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186104
CYP2S1
GeneProduct
ENSBTAG00000018240 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000167600
CYP2U1
GeneProduct
ENSBTAG00000012972 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000155016
CYP2W1
GeneProduct
ENSBTAG00000017701 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000073067
CYP39A1
GeneProduct
ENSBTAG00000003632 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146233
CYP3A43
GeneProduct
ENSBTAG00000047379 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000021461
CYP3A4
GeneProduct
ENSBTAG00000047379 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000160868
CYP3A5
GeneProduct
ENSBTAG00000047379 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106258
CYP3A7
GeneProduct
ENSBTAG00000047379 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000160870
CYP46A1
GeneProduct
ENSBTAG00000035544 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000036530
CYP4A11
GeneProduct
ENSBTAG00000000229 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000187048
CYP4A22
GeneProduct
ENSBTAG00000000229 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000162365
CYP4B1
GeneProduct
ENSBTAG00000011976 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000142973
CYP4F11
GeneProduct
ENSBTAG00000038549 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000171903
CYP4F12
GeneProduct
ENSBTAG00000038549 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186204
CYP4F22
GeneProduct
ENSBTAG00000047933 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000171954
CYP4F2
GeneProduct
ENSBTAG00000038549 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186115
CYP4F3
GeneProduct
ENSBTAG00000038549 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186529
CYP4F3
GeneProduct
ENSBTAG00000048257 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186526
CYP4V2
GeneProduct
ENSBTAG00000021263 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000145476
CYP4X1
GeneProduct
ENSBTAG00000015647 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186377
CYP4Z1
GeneProduct
CYP51A1
GeneProduct
ENSBTAG00000001992 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000001630
CYP7A1
GeneProduct
ENSBTAG00000005287 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000167910
CYP7B1
GeneProduct
ENSBTAG00000001299 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000172817
CYP8B1
GeneProduct
ENSBTAG00000034106 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000180432
CYP
GeneProduct
ENSBTAG00000020375 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1559
Fe2+
Metabolite
CHEBI:29033 (ChEBI)
Fe3+
Metabolite
CHEBI:29034 (ChEBI)
H2O
Metabolite
HMDB0002111 (HMDB)
MGC127055
GeneProduct
ENSBTAG00000026501 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000100197
NAD+
Metabolite
CHEBI:15846 (ChEBI)
NADH
Metabolite
CHEBI:16908 (ChEBI)
NADP+
Metabolite
CHEBI:18009 (ChEBI)
NADPH
Metabolite
CHEBI:16474 (ChEBI)
O2
Metabolite
HMDB0001377 (HMDB)
POR
GeneProduct
ENSBTAG00000017082 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000127948
Substrate-OH
Metabolite
Q542929 (Wikidata)
Substrate
Metabolite
Q12119506 (Wikidata)
activated O2
Metabolite
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
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No annotated interactions