T cell receptor signaling pathway (Canis familiaris)

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(Protein-protein interaction)DCY->PMGlycosylationMTAntigenNUMethylationCY->NUPlasma membraneCYDTranslocationExtracellularEndoplasmic reticulumSumoylationMolecular associationDesumoylationLigandUbiquitinationAcetylationActivationDeacetylationDephosphorylationMitochondrionControlDemethylationCytoplasmRecruitmentReceptorPMInhibitionDeubiquitinationPalmitoylationReaction through unknown mechanisms/moleculesProteolytic cleavageEREndosomeEnzyme complexECGene SymbolCY->NUAutophosphorylationGOProteins in a complex interactionNucleusGolgi apparatusPhosphorylationENMolecule in the pathwayNU->CYAccession Number: NetPath_11ACP1RAP1APIK3R2PTK2BZAP70VAV2TRA@ITPR1NFATC2WIPF1CRKLLOC478556PTPN11PLCG1SLA2PTPN12LOC487343LYNLIME1CTNNB1HOMER3PTPRJCABIN1CISHLCKRAPGEF1CD3ESOS2ENAHSHBCD2APVAV1CD3ZCREBBPDNM2ARHGDIBSKAP2PTPN6CD4STAT1DEF6LOC486589UNC119LAX1TUBA4ADUSP3CARD11NCLLOC607448SH3BP2SIT1FYNLOC486589ABI1NCK1SLAMAP4K1DTX1SOS1PAG1FYBBCL10AKT1PAK1ARHGEF6JUNTRB@DLG1FOSGIT2RASGRP2PTPN22CD3ZMAP2K1DBNLNCK1GRB2MAPK3MUC1PPP3CBCRKPTK2MAP2K2MAPK7PXNCD3ESYKKHDRBS1YWHAQSRCSTAT5AVASPSTAT5BPSTPIP1MAP3K1PRKD2VAV3NEDD9FCRL3SH2D3CLCP2LNKGRAP2ARHGEF7STAT5BLATRIPK2PTPRHGRAPLOC489383GAB2CBLPIK3R1DOCK2LOC479419PRKCQRAC2RASA1PTPRCBRAFSH2D2APTPN3STK39SKAP1SHC1WASCDC42TUBBSTAT5ALCP2TXKITKLIME1CD8AFYBEVLCD5MAPK1JAK3CEBPBCBLBJUNABL1CREB1NFAM1


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 85% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
118024view11:42, 23 May 2021EweitzModified title
87696view08:58, 25 July 2016MirellaKalafatiOntology Term : 'signaling pathway' added !
87695view08:57, 25 July 2016MirellaKalafatiOntology Term : 'T cell' added !
68566view22:51, 5 July 2013MaintBotUpdated to 2013 gpml schema
40724view21:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
34003view18:39, 9 December 2009MaintBotAutomatic update of empty xrefs
32562view13:09, 17 August 2009MaintBotFixed text labels
31260view19:54, 13 August 2009MaintBotFixed text labels
30699view22:48, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI1GeneProduct607247 (Entrez Gene)
ABL1GeneProduct491292 (Entrez Gene)
ACP1GeneProduct
AKT1GeneProduct490878 (Entrez Gene)
ARHGDIBGeneProduct486666 (Entrez Gene)
ARHGEF6GeneProduct610290 (Entrez Gene)
ARHGEF7GeneProduct485552 (Entrez Gene)
BCL10GeneProduct490183 (Entrez Gene)
BRAFGeneProduct475526 (Entrez Gene)
CABIN1GeneProduct486403 (Entrez Gene)
CARD11GeneProduct489887 (Entrez Gene)
CBLGeneProduct
CBLBGeneProduct487965 (Entrez Gene)
CD2APGeneProduct474928 (Entrez Gene)
CD3EGeneProduct442981 (Entrez Gene)
CD3ZGeneProduct
CD4GeneProduct403931 (Entrez Gene)
CD5GeneProduct612338 (Entrez Gene)
CD8AGeneProduct403157 (Entrez Gene)
CDC42GeneProduct607535 (Entrez Gene)
CEBPBGeneProduct
CISHGeneProduct484757 (Entrez Gene)
CREB1GeneProduct607922 (Entrez Gene)
CREBBPGeneProduct479866 (Entrez Gene)
CRKGeneProduct
CRKLGeneProduct608125 (Entrez Gene)
CTNNB1GeneProduct477032 (Entrez Gene)
DBNLGeneProduct607412 (Entrez Gene)
DEF6GeneProduct
DLG1GeneProduct488036 (Entrez Gene)
DNM2GeneProduct484949 (Entrez Gene)
DOCK2GeneProduct489128 (Entrez Gene)
DTX1GeneProduct
DUSP3GeneProduct480505 (Entrez Gene)
ENAHGeneProduct
EVLGeneProduct480433 (Entrez Gene)
FCRL3GeneProduct612046 (Entrez Gene)
FOSGeneProduct490792 (Entrez Gene)
FYBGeneProduct479355 (Entrez Gene)
FYNGeneProduct475032 (Entrez Gene)
GAB2GeneProduct485167 (Entrez Gene)
GIT2GeneProduct477520 (Entrez Gene)
GRAP2GeneProduct481241 (Entrez Gene)
GRAPGeneProduct489534 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
HOMER3GeneProduct484813 (Entrez Gene)
ITKGeneProduct489159 (Entrez Gene)
ITPR1GeneProduct476548 (Entrez Gene)
JAK3GeneProduct610004 (Entrez Gene)
JUNGeneProduct609429 (Entrez Gene)
KHDRBS1GeneProduct487316 (Entrez Gene)
LATGeneProduct607947 (Entrez Gene)
LAX1GeneProduct
LCKGeneProduct478151 (Entrez Gene)
LCP2GeneProduct489126 (Entrez Gene)
LIME1GeneProduct
LNKGeneProduct
LOC478556GeneProduct478556 (Entrez Gene)
LOC479419GeneProduct479419 (Entrez Gene)
LOC486589GeneProduct486589 (Entrez Gene)
LOC487343GeneProduct487343 (Entrez Gene)
LOC489383GeneProduct489383 (Entrez Gene)
LOC607448GeneProduct607448 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAP3K1GeneProduct478061 (Entrez Gene)
MAP4K1GeneProduct484527 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK7GeneProduct489532 (Entrez Gene)
MUC1GeneProduct448784 (Entrez Gene)
NCK1GeneProduct485677 (Entrez Gene)
NCLGeneProduct608445 (Entrez Gene)
NEDD9GeneProduct488220 (Entrez Gene)
NFAM1GeneProduct609583 (Entrez Gene)
NFATC2GeneProduct485930 (Entrez Gene)
PAG1GeneProduct610895 (Entrez Gene)
PAK1GeneProduct607885 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PLCG1GeneProduct485874 (Entrez Gene)
PPP3CBGeneProduct479248 (Entrez Gene)
PRKCQGeneProduct478013 (Entrez Gene)
PRKD2GeneProduct484427 (Entrez Gene)
PSTPIP1GeneProduct
PTK2GeneProduct475108 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PTPN12GeneProduct483277 (Entrez Gene)
PTPN22GeneProduct483124 (Entrez Gene)
PTPN3GeneProduct610692 (Entrez Gene)
PTPN6GeneProduct486717 (Entrez Gene)
PTPRCGeneProduct490255 (Entrez Gene)
PTPRHGeneProduct
PTPRJGeneProduct483617 (Entrez Gene)
PXNGeneProduct486299 (Entrez Gene)
RAC2GeneProduct481271 (Entrez Gene)
RAP1AGeneProduct483225 (Entrez Gene)
RAPGEF1GeneProduct491286 (Entrez Gene)
RASA1GeneProduct479158 (Entrez Gene)
RASGRP2GeneProduct612101 (Entrez Gene)
RIPK2GeneProduct477936 (Entrez Gene)
SH2D2AGeneProduct
SH2D3CGeneProduct491326 (Entrez Gene)
SH3BP2GeneProduct488797 (Entrez Gene)
SHBGeneProduct481619 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SIT1GeneProduct611919 (Entrez Gene)
SKAP1GeneProduct480543 (Entrez Gene)
SKAP2GeneProduct482366 (Entrez Gene)
SLA2GeneProduct485859 (Entrez Gene)
SLAGeneProduct608259 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
SOS2GeneProduct490682 (Entrez Gene)
SRCGeneProduct485864 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)
STK39GeneProduct478779 (Entrez Gene)
SYKGeneProduct484196 (Entrez Gene)
TRA@GeneProduct
TRB@GeneProduct
TUBA4AGeneProduct478918 (Entrez Gene)
TUBBGeneProduct474830 (Entrez Gene)
TXKGeneProduct482139 (Entrez Gene)
UNC119GeneProduct491169 (Entrez Gene)
VASPGeneProduct403936 (Entrez Gene)
VAV1GeneProduct485016 (Entrez Gene)
VAV2GeneProduct608060 (Entrez Gene)
VAV3GeneProduct479921 (Entrez Gene)
WASGeneProduct491867 (Entrez Gene)
WIPF1GeneProduct488409 (Entrez Gene)
YWHAQGeneProduct607060 (Entrez Gene)
ZAP70GeneProduct100271860 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1130"
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