Regulation of cardiac hypertrophy by miR-208 (Mus musculus)
From WikiPathways
Description
MicroRNA-208a regulates cardiac hypertrophy pathways in mice.
MicroRNAs are shown in purple. Knock out and overexpression of miR-208a are shown in blue. Processes are shown at the top and include hypertrophy, atrial fibrilation and prolonged PR interval & abberand conduction.
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Ontology Terms
Bibliography
- Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ; ''MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.''; J Clin Invest, 2009 PubMed Europe PMC Scholia
- Lo CW; ''Role of gap junctions in cardiac conduction and development: insights from the connexin knockout mice.''; Circ Res, 2000 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Cx40 | Protein | 14613 (Entrez Gene) | |
Gata4 | GeneProduct | 14463 (Entrez Gene) | |
Hop | GeneProduct | 74318 (Entrez Gene) | |
Myostatin | Protein | 17700 (Entrez Gene) | |
Trap1 | Protein | 327987 (Entrez Gene) | |
beta-MHC | GeneProduct | 140781 (Entrez Gene) | |
miR-208a | Rna | MI0000555 (miRBase Sequence) | |
miR-208b | Rna | ENSMUSG00000077928 (Ensembl) | MI0005552 |
Annotated Interactions
No annotated interactions