Arylhydrocarbon receptor (AhR) signaling pathway (Bos taurus)
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Carcinogen
XRE
EGFR pathway
CDKN1B
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IGFBP1
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filaggrin
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AHR
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AIP
SRC
SRC
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AHR
TATA
ARNT
AHR
Cell proliferation
and differentiation
Biotransformation
Genes
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP2100(74081)
with a 92.0% conversion rate.
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Bibliography
Rowlands JC, Gustafsson JA; ''Aryl hydrocarbon receptor-mediated signal transduction.''; Crit Rev Toxicol, 1997
PubMed
Europe PMC
Scholia
Bock KW, Köhle C; ''Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions.''; Biochem Pharmacol, 2006
PubMed
Europe PMC
Scholia
Haarmann-Stemmann T, Bothe H, Abel J; ''Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways.''; Biochem Pharmacol, 2009
PubMed
Europe PMC
Scholia
History
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80804
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15:26, 30 June 2015
Mkutmon
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AHR
GeneProduct
ENSBTAG00000007746 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106546
AHRR
GeneProduct
ENSBTAG00000026527 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000063438
AIP
GeneProduct
ENSBTAG00000010478 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110711
ALDH3A1
GeneProduct
ENSBTAG00000021113 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108602
ARNT
GeneProduct
ENSBTAG00000021037 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:405
BAX
GeneProduct
ENSBTAG00000013340 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000087088
CDC37
GeneProduct
ENSBTAG00000011699 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105401
CDKN1A
GeneProduct
ENSBTAG00000008353 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000124762
CDKN1B
GeneProduct
ENSBTAG00000018254 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111276
CYP1A1
GeneProduct
ENSBTAG00000001021 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140465
CYP1A2
GeneProduct
ENSBTAG00000000085 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505
CYP1B1
GeneProduct
ENSBTAG00000010531 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
Carcinogen
Metabolite
CHEBI:50903 (ChEBI)
EGFR
GeneProduct
ENSBTAG00000011628 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146648
GSTA2
GeneProduct
ENSBTAG00000006546 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000244067
HES1
GeneProduct
ENSBTAG00000000569 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000114315
HSP90AA1
GeneProduct
ENSBTAG00000006270 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000080824
IGFBP1
GeneProduct
ENSBTAG00000046768 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146678
IL2
GeneProduct
ENSBTAG00000020883 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000109471
JUND
GeneProduct
JUN
GeneProduct
ENSBTAG00000004037 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000177606
NFE2L2
GeneProduct
ENSBTAG00000019255 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116044
NQO1
GeneProduct
ENSBTAG00000020632 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000181019
PTGES3
GeneProduct
ENSBTAG00000017967 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110958
SRC
GeneProduct
ENSBTAG00000008938 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197122
TNF
GeneProduct
ENSBTAG00000025471 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000232810
UGT1A1
GeneProduct
ENSBTAG00000026181 (Ensembl)
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000241635
UGT1A6
GeneProduct
filaggrin
GeneProduct
Annotated Interactions
No annotated interactions
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