Isoleucine and valine biosynthesis (Saccharomyces cerevisiae)
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alpha-isopropylmalate
2-oxoglutarate
2-oxoglutarate
H+
2-keto-isovalerate
H+
CO2
NADP
NH3
2 pyruvate
2-keto-3-methyl-valerate
CO2
H2O
beta-isopropylmalate
CO2
2-oxobutanoate
2-aceto-lactate
H2O
H2O
pyruvate
2-oxoglutarate
alpha-ketoisocaproate
H2O
L-iso-leucine
H+
2,3-dihydroxy-3-methylvalerate
L-glutarate
NADP
2-aceto-2-hydroxy-butyrate
2,3-dihydroxy-isovalerate
NAD
H2O
NADPH
L-glutamate
ILV3
ILV6
BAT1
ILV1
Coenzyme A
LEU4
BAT2
NADPH
L-leucine
LEU2
NADH
ILV5
BAT1
LEU1
ILV5
ILV2
BAT2
ILV2
ILV6
ILV3
L-Valine
BAT1
L-threonine
BAT2
acetyl-CoA
L-glutamate
LEU9
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
117304
view
11:18, 20 May 2021
Eweitz
Modified title
89665
view
05:48, 24 September 2016
Egonw
Replace the CAS number of the salt with that of just the metabolite.
69861
view
17:24, 11 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
69626
view
20:35, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67415
view
10:58, 26 June 2013
Ddigles
Ontology Term : 'valine, leucine and isoleucine biosynthetic pathway' added !
41861
view
04:51, 2 March 2011
MaintBot
Removed redundant pathway information and comments
21431
view
11:31, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:Isoleucine Valine Biosynthesis]] moved to [[Pathway:WP359]]: Moved to stable identifier
12756
view
08:01, 17 May 2008
MaintBot
automated metabolite conversion
8795
view
14:09, 7 January 2008
MaintBot
Added to category $category
8793
view
14:09, 7 January 2008
J.Heckman
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
BAT1
GeneProduct
S000001251 (SGD)
BAT2
GeneProduct
S000003909 (SGD)
Coenzyme A
Metabolite
64885-97-8 (CAS)
ILV1
GeneProduct
S000000888 (SGD)
ILV2
GeneProduct
S000004714 (SGD)
ILV3
GeneProduct
S000003777 (SGD)
ILV5
GeneProduct
S000004347 (SGD)
ILV6
GeneProduct
S000000515 (SGD)
L-Valine
Metabolite
72-18-4 (CAS)
L-glutamate
Metabolite
56-86-0 (CAS)
L-leucine
Metabolite
61-90-5 (CAS)
L-threonine
Metabolite
72-19-5 (CAS)
LEU1
GeneProduct
S000002977 (SGD)
LEU2
GeneProduct
S000000523 (SGD)
LEU4
GeneProduct
S000005048 (SGD)
LEU9
GeneProduct
S000005634 (SGD)
minor isozyme
NADH
Metabolite
53-84-9 (CAS)
NADPH
Metabolite
53-57-6 (CAS)
acetyl-CoA
Metabolite
72-89-9 (CAS)
Annotated Interactions
No annotated interactions
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