Glycolysis and gluconeogenesis (Apis cerana)

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Description

Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO- and H+. The free energy released in this process is used to form the ATP and NADH.

Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids. Description adapted from [Wikipedia](http://www.wikipedia.org).

The original pathway (https://www.wikipathways.org/pathways/WP534) was lifted into Apis cerana.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J; ''A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.''; Science, 2012 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
142542view10:02, 16 March 2026Kotaro470change author
142536view09:49, 16 March 2026Kotaro470change the organism
142520view10:48, 13 March 2026Kotaro470New pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1,3BP-GlycerateMetaboliteHMDB0001270 (HMDB)
2P-GlycerateMetaboliteHMDB0000362 (HMDB)
3P-GlycerateMetaboliteHMDB0000807 (HMDB)
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
Ald1GeneProduct107994885 (Entrez Gene)
AspartateMetaboliteHMDB0000191 (HMDB)
DLDGeneProductSTRG.5224.1 (Other)
Dihydroxyacetone-PMetaboliteHMDB0001473 (HMDB)
ENO3GeneProductSTRG.4002.1 (Other)
EnoGeneProduct108002642 (Entrez Gene)
Fructose 6P (open)MetaboliteCHEBI:57579 (ChEBI) fructose-6-phosphate (2-) open form
Fructose 6PMetaboliteCHEBI:61527 (ChEBI)
Fructose-1,6BPMetaboliteHMDB0001058 (HMDB)
GAPDHGeneProductSTRG.2341.1 (Other)
GCKGeneProductSTRG.10060.11 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.12 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.13 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.14 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.16 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.17 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.18 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.1 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.2 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.3 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.4 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.5 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.6 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.7 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.8 (Other) Gck is mainly active in liver
GCKGeneProductSTRG.10060.9 (Other) Gck is mainly active in liver
GCKGeneProductg10034.t1 (Other) Gck is mainly active in liver
GOT1GeneProductSTRG.4583.1 (Other)
GOT1GeneProductSTRG.4583.2 (Other)
GOT1GeneProductg4619.t1 (Other)
GOT2GeneProductg10960.t1 (Other)
GPIGeneProductSTRG.538.1 (Other) glucose-6-phosphate isomerase
GPIGeneProductSTRG.538.2 (Other) glucose-6-phosphate isomerase
GPIGeneProductSTRG.538.3 (Other) glucose-6-phosphate isomerase
GPIGeneProductg405.t1 (Other) glucose-6-phosphate isomerase
Glucose-6P (open)MetaboliteCHEBI:57584 (ChEBI) D-Glucose-6-Phosphate (2-) open form
Glucose-6PMetaboliteCHEBI:75052 (ChEBI) Glucose-6-Phosphate (2-)
GlucoseMetaboliteHMDB0000122 (HMDB)
Glut1GeneProduct107999331 (Entrez Gene)
Glyceraldehyde 3PMetaboliteHMDB0001112 (HMDB)
Glycogen metabolismPathwayWP500 (WikiPathways)
Hex-AGeneProduct108000730 (Entrez Gene)
LOC107996114GeneProduct107996114 (Entrez Gene)
LOC107997339GeneProduct107997339 (Entrez Gene)
LOC107999802GeneProduct107999802 (Entrez Gene)
LOC108000456GeneProduct108000456 (Entrez Gene)
LactateMetaboliteHMDB0000190 (HMDB)
MDH1GeneProductSTRG.9701.1 (Other)
MDH1GeneProductSTRG.9701.3 (Other)
MDH2GeneProductSTRG.8124.2 (Other)
MDH2GeneProductg1039.t1 (Other)
MDH2GeneProductg4094.t1 (Other)
MDH2GeneProductg8087.t1 (Other)
MPC1GeneProductg1222.t1 (Other)
MPC2GeneProductSTRG.6836.3 (Other)
MalateMetaboliteHMDB0000744 (HMDB)
OxaloacetateMetaboliteHMDB0000223 (HMDB)
P-enolpyruvateMetaboliteHMDB0000263 (HMDB)
PCBGeneProduct108004016 (Entrez Gene)
PDHA1GeneProductSTRG.3951.1 (Other)
PDHA1GeneProductSTRG.741.1 (Other)
PDHA1GeneProductg612.t1 (Other)
PFKPGeneProductSTRG.2400.1 (Other)
PFKPGeneProductSTRG.2400.2 (Other)
PFKPGeneProductSTRG.2400.3 (Other)
PFKPGeneProductSTRG.2400.4 (Other)
PFKPGeneProductSTRG.2400.5 (Other)
PFKPGeneProductSTRG.2400.6 (Other)
PFKPGeneProductg2352.t1 (Other)
PGAM1GeneProductg4531.t1 (Other)
PGAM2GeneProduct108000761 (Entrez Gene)
PGIGeneProduct5.3.1.9 (Enzyme Nomenclature) phosphoglucose isomerase (PGI)
PGK1GeneProductg5409.t1 (Other)
Pentose phosphate pathwayPathwayWP134 (WikiPathways)
PfkGeneProduct108003046 (Entrez Gene)
PgkGeneProduct107993693 (Entrez Gene)
PyruvateMetaboliteHMDB0000243 (HMDB)
SLC2A1GeneProductSTRG.3262.2 (Other)
SLC2A1GeneProductSTRG.8499.10 (Other)
SLC2A1GeneProductSTRG.8499.11 (Other)
SLC2A1GeneProductSTRG.8499.12 (Other)
SLC2A1GeneProductSTRG.8499.13 (Other)
SLC2A1GeneProductSTRG.8499.14 (Other)
SLC2A1GeneProductSTRG.8499.15 (Other)
SLC2A1GeneProductSTRG.8499.16 (Other)
SLC2A1GeneProductSTRG.8499.17 (Other)
SLC2A1GeneProductSTRG.8499.18 (Other)
SLC2A1GeneProductSTRG.8499.19 (Other)
SLC2A1GeneProductSTRG.8499.1 (Other)
SLC2A1GeneProductSTRG.8499.20 (Other)
SLC2A1GeneProductSTRG.8499.24 (Other)
SLC2A1GeneProductSTRG.8499.25 (Other)
SLC2A1GeneProductSTRG.8499.26 (Other)
SLC2A1GeneProductSTRG.8499.29 (Other)
SLC2A1GeneProductSTRG.8499.30 (Other)
SLC2A1GeneProductSTRG.8499.32 (Other)
SLC2A1GeneProductSTRG.8499.33 (Other)
SLC2A1GeneProductSTRG.8499.3 (Other)
SLC2A1GeneProductSTRG.8499.4 (Other)
SLC2A1GeneProductSTRG.8499.6 (Other)
SLC2A1GeneProductSTRG.8499.7 (Other)
SLC2A1GeneProductSTRG.8499.8 (Other)
SLC2A1GeneProductSTRG.8499.9 (Other)
SLC2A1GeneProductg7248.t1 (Other)
SLC2A3GeneProductSTRG.3850.1 (Other)
SLC2A3GeneProductg3842.t1 (Other)
SLC2A4GeneProductSTRG.5504.1 (Other)
SLC2A4GeneProductSTRG.5504.6 (Other)
SLC2A4GeneProductSTRG.5504.8 (Other)
SLC2A4GeneProductg5569.t1 (Other)
TCA cyclePathwayWP78 (WikiPathways)
TPI1GeneProductSTRG.5313.1 (Other)
TPI1GeneProductg5378.t1 (Other)
Triglyceride synthesisPathwayWP325 (WikiPathways)
fbpGeneProduct107994224 (Entrez Gene)
mucGeneProduct107995101 (Entrez Gene)

Annotated Interactions

No annotated interactions

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