Blood clotting cascade (Gallus gallus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Factor XIIaFactor XIaFactor VIIIaFactor IXaFactor XaFactor VaThrombinFibrin MonomerFactor XIIIaFibrin PolymerFactor VIIaIntrinsic PathwayExtrinsic PathwayTissue FactorPlasminFibrin Split Products+ThrombolysisTissue InjuryF12F11F9VWFF5F7F2F13BSERPINF2PLAUPLATPLGProthrombinase ComplexFibrinF10F10FGBFGAFGGSERPINB2SERPINE1F8F8A1Name: Blood clotting cascadeLast Modified: 5/1/2013Organism: Gallus gallus


Description

Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [Wikipedia](https://en.wikipedia.org/wiki/Coagulation)

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP272(r30179) with a 73% conversion rate.

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Quality Tags

Image:MissingXref.pngAnnotate nodes
Image:Curated.pngApproved version
Homology Converted

Ontology Terms

 

Bibliography

  1. Luchtman-Jones L, Broze GJ Jr; ''The current status of coagulation.''; Ann Med, 1995 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
136902
Approved
view19:24, 26 February 2025KhanspersModified description
117189view10:31, 18 May 2021EweitzModified title
72063view17:29, 24 October 2013MaintBotremoved data source from nodes without identifier
68812view17:15, 8 July 2013MaintBotUpdated to 2013 gpml schema
67095view10:05, 26 June 2013Christine ChichesterOntology Term : 'coagulation cascade pathway' added !
62669view18:31, 1 May 2013MaintBotUpdated Ensembl and UniProt data source
40946view22:53, 1 March 2011MaintBotRemoved redundant pathway information and comments
35086view12:31, 11 February 2010Thomasfixed group positions, removed incorrect line
35082view12:25, 11 February 2010Thomasadded literature, fixed lines
35071view12:03, 11 February 2010ThomasModified description
33874view17:51, 9 December 2009MaintBotAutomatic update of empty xrefs
33457view15:01, 30 November 2009MaintBotRemoved group label
30344view20:50, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
F10GeneProduct395876 (Entrez Gene)
F11GeneProduct422723 (Entrez Gene)
F12GeneProduct
F13BGeneProduct424355 (Entrez Gene)
F2GeneProduct395306 (Entrez Gene)
F5GeneProduct374052 (Entrez Gene)
F7GeneProduct395086 (Entrez Gene)
F8GeneProduct422199 (Entrez Gene)
F8A1GeneProduct
F9GeneProduct374258 (Entrez Gene)
FGAGeneProduct396307 (Entrez Gene)
FGBGeneProduct373926 (Entrez Gene)
FGGGeneProduct395837 (Entrez Gene)
FibrinMetabolite
PLATGeneProduct426791 (Entrez Gene)
PLAUGeneProduct396424 (Entrez Gene)
PLGGeneProduct421580 (Entrez Gene)
Prothrombinase ComplexGeneProduct
SERPINB2GeneProduct420896 (Entrez Gene)
SERPINE1GeneProduct
SERPINF2GeneProduct417561 (Entrez Gene)
VWFGeneProduct419031 (Entrez Gene)

Annotated Interactions

No annotated interactions
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