Oxidative stress response (Pan troglodytes)
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Inhibition of oxidases
Immediate-early
gene induction
TF activation
Reactive Oxygen Species
TF inhibition
Activation
Adaptive response
Stress-regulated MAP kinase
Induction of
antioxidant genes
Repression of ROS-
producing systems
Repression
UGT1A6
MAOA
SP1
SOD3
FOS
MGST1
GSR
MT1X
GCLC
NFIX
NQO1
JUNB
LOC453744
SOD2
GPX3
CAT
TXNRD2
SOD1
HMOX1
NFKB1
TXN2
GPX1
MAPK10
XDH
TXNRD1
GSTT2
Nrf2
MAPK14
LOC468068
Description
No description
Comments
GenMAPP notes
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks
Adapted from rat by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP408(r21540)
with a 79% conversion rate.
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
117037
view
14:11, 16 May 2021
Eweitz
Modified title
88285
view
14:42, 1 August 2016
Fehrhart
Ontology Term : 'oxidative stress response pathway' added !
71669
view
19:40, 17 October 2013
MaintBot
Automated update of data sources
69251
view
18:36, 8 July 2013
MaintBot
Updated to 2013 gpml schema
41558
view
01:59, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34289
view
22:01, 9 December 2009
MaintBot
Automatic update of empty xrefs
33584
view
09:50, 1 December 2009
MaintBot
Removed group label
31607
view
22:12, 13 August 2009
MaintBot
Fixed text labels
30501
view
21:42, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CAT
GeneProduct
451116 (Entrez Gene)
FOS
GeneProduct
453047 (Entrez Gene)
GCLC
GeneProduct
742732 (Entrez Gene)
GPX1
GeneProduct
461015 (Entrez Gene)
GPX3
GeneProduct
471703 (Entrez Gene)
GSR
GeneProduct
464099 (Entrez Gene)
GSTT2
GeneProduct
458962 (Entrez Gene)
HMOX1
GeneProduct
470195 (Entrez Gene)
JUNB
GeneProduct
468739 (Entrez Gene)
LOC453744
GeneProduct
453744 (Entrez Gene)
LOC468068
GeneProduct
468068 (Entrez Gene)
Probe set ID: u18729
MAOA
GeneProduct
740491 (Entrez Gene)
MAPK10
GeneProduct
461358 (Entrez Gene)
MAPK14
GeneProduct
450161 (Entrez Gene)
MGST1
GeneProduct
473380 (Entrez Gene)
MT1X
GeneProduct
736020 (Entrez Gene)
NFIX
GeneProduct
NFKB1
GeneProduct
461406 (Entrez Gene)
NQO1
GeneProduct
468012 (Entrez Gene)
Nrf2
GeneProduct
SOD1
GeneProduct
449637 (Entrez Gene)
SOD2
GeneProduct
449634 (Entrez Gene)
SOD3
GeneProduct
461143 (Entrez Gene)
SP1
GeneProduct
451939 (Entrez Gene)
TXN2
GeneProduct
TXNRD1
GeneProduct
467112 (Entrez Gene)
TXNRD2
GeneProduct
458654 (Entrez Gene)
UGT1A6
GeneProduct
739942 (Entrez Gene)
XDH
GeneProduct
470347 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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