Oxidative stress response (Mus musculus)
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Immediate-early
gene induction
repression
Reactive Oxygen Species
TF activation
Activation
Stress-regulated MAP kinase
Repression of ROS-
producing systems
TF inhibition
Adaptive response
Induction of
antioxidant genes
Inhibition of oxidases
Gclc
Cat
Txn2
Nfkb1
Mapk10
Fos
Junb
NRF2B1
Hmox1
Ugt1a1
Gstt2
Xdh
Mgst1
Gpx3
Cyp1a1
Mt1
Sod2
Gsr
Nfix
Mapk14
Sp1
Nqo1
Sod3
Maoa
Cyba
Txnrd1
Gpx1
Sod1
Txnrd2
Description
No description
Comments
GenMAPP notes
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks
Adapted from rat by GenMAPP.org
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History
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Compare
Revision
Action
Time
User
Comment
117038
view
14:11, 16 May 2021
Eweitz
Modified title
89965
view
18:18, 6 October 2016
Mkutmon
fix unconnected lines
69190
view
18:22, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67564
view
11:26, 26 June 2013
Ddigles
Ontology Term : 'oxidative stress response pathways' added !
41381
view
00:28, 2 March 2011
MaintBot
Removed redundant pathway information and comments
33386
view
14:42, 30 November 2009
MaintBot
Removed group label
33043
view
21:34, 7 October 2009
MaintBot
one more connector
33042
view
21:33, 7 October 2009
MaintBot
added connectors
29168
view
12:04, 9 April 2009
Evelo
Added annotations for SOD1, NRF2 (should be checked) and UGT1a
29166
view
11:49, 9 April 2009
Evelo
Cosmetic
21550
view
11:32, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Oxidative Stress]] moved to [[Pathway:WP412]]: Moved to stable identifier
8320
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Oxidative Stress]] moved to [[Pathway:Mus musculus:Oxidative Stress]]: Renaming species
7778
view
16:17, 18 December 2007
MaintBot
fixed category names
7483
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
19532
view
22:19, 22 May 2007
I.Reyes
gpml file for [[Mouse:Oxidative_Stress]]
6484
view
22:19, 22 May 2007
N.Reyes
gpml file for [[Mouse:Oxidative_Stress]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Cat
GeneProduct
12359 (Entrez Gene)
Cyba
GeneProduct
13057 (Entrez Gene)
Probe set ID: u18729
Cyp1a1
GeneProduct
13076 (Entrez Gene)
Fos
GeneProduct
14281 (Entrez Gene)
Gclc
GeneProduct
14629 (Entrez Gene)
Gpx1
GeneProduct
14775 (Entrez Gene)
Gpx3
GeneProduct
14778 (Entrez Gene)
Gsr
GeneProduct
14782 (Entrez Gene)
Gstt2
GeneProduct
14872 (Entrez Gene)
Hmox1
GeneProduct
15368 (Entrez Gene)
Junb
GeneProduct
16477 (Entrez Gene)
Maoa
GeneProduct
17161 (Entrez Gene)
Mapk10
GeneProduct
26414 (Entrez Gene)
Mapk14
GeneProduct
26416 (Entrez Gene)
Mgst1
GeneProduct
56615 (Entrez Gene)
Mt1
GeneProduct
17748 (Entrez Gene)
NRF2B1
GeneProduct
14391 (Entrez Gene)
Nfix
GeneProduct
18032 (Entrez Gene)
Nfkb1
GeneProduct
18033 (Entrez Gene)
Nqo1
GeneProduct
18104 (Entrez Gene)
Sod1
GeneProduct
20655 (Entrez Gene)
Sod2
GeneProduct
20656 (Entrez Gene)
Sod3
GeneProduct
20657 (Entrez Gene)
Sp1
GeneProduct
20683 (Entrez Gene)
Txn2
GeneProduct
56551 (Entrez Gene)
Txnrd1
GeneProduct
50493 (Entrez Gene)
Txnrd2
GeneProduct
26462 (Entrez Gene)
Ugt1a1
GeneProduct
394436 (Entrez Gene)
Xdh
GeneProduct
29289 (Entrez Gene)
Annotated Interactions
No annotated interactions
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