AOP416 KEs (Homo sapiens)

Description

Overview of key events of AOP416 from AOPwiki.org

View approved pathways at the new wikipathways.org.

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Name	Type	Database reference	Comment
Activation, AhR	Event	18 (AOP-Wiki KE)	Activation, AhR Type your comment here
Altered gene expression, NF-kB dependent Interleukin-6 pathway	Event	1921 (AOP-Wiki KE)	Altered gene expression, NF-kB dependent Interleukin-6 pathway Type your comment here
Ethanol metabolism production of ROS by CYP2E1	Pathway	WP4269 (WikiPathways)
Increase, Reactive Oxygen species	Event	1115 (AOP-Wiki KE)	Increase, Reactive Oxygen species Type your comment here
Increased, DNA damage and mutation	Event	1669 (AOP-Wiki KE)	Increased, DNA damage and mutation Type your comment here
Increased, Interleukin-6 production	Event	1933 (AOP-Wiki KE)	Increased, Interleukin-6 production Type your comment here
Interleukin-6 family signaling	Pathway	WP4122 (WikiPathways)
Lung cancer	Event	1670 (AOP-Wiki KE)	Lung cancer Type your comment here
non-small cell lung cancer	Pathway	WP4255 (WikiPathways)

No annotated interactions

Compare	Revision	Action	Time	User	Comment
	139100	view	12:23, 20 May 2025	Maick Helmes	Ontology Term : 'lung cancer' added !
	139092	view	11:55, 20 May 2025	Maick Helmes	New pathway