Cytokines and inflammatory response (Pan troglodytes)
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Clonal expansion of T cells
NK cell
Tc
Eos
Tc
Hypothalamus
(fever)
B Cell
Tc
B Cell
B Cell
Th
B Cell
Hematopoietic Stem Cell
MHC II
Eos
T-helper
Hematopoiesis
antigen
Plasma Cell
Eos
Th
Macrophage
antibodies
Neutrophil
Th
Endothelial Cells
TCR
T-helper
Mast Cell
Lymphocyte Activated
Killer Cells (LAK)
Fibroblasts
IL15
IL4
IFNG
LOC473183
IFNG
IL13
IL5
IL3
IFN1@
IL6
IL4
IL1B
IL2
IL15
IL10
IFNG
IL1A
IL1A
IL7
IL4
IL15
TRB
IL10
IL5
CSF2
TRA
PDGFA
IL12B
PATR-DRA
IL1A
TNF
IL2
IL6
IL6
CXCL2
TNF
TGFB1
IL6
Inflammatory Response
TNF
CXCL1
IL1B
TGFB1
CD4
IL2
IL2
IL1A
IL1B
IL1B
IL3
IL11
IL2
IFN1@
CSF3
IL4
IL12
TNF
IL10
IL1A
IL2
IL6
IL12B
IL10
CSF2
TNF
IL4
HLA-DRB1
IL3
IL13
IL1B
IL2
TGFB1
TNF
IL3
CSF1
TNF
Description
See BioCarta version:
http://www.biocarta.com/pathfiles/h_inflamPathway.asp
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP530(r21794)
with a 80% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
Kataoka T; ''Chemical biology of inflammatory cytokine signaling.''; J Antibiot (Tokyo), 2009
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117385
view
10:32, 21 May 2021
Eweitz
Modified title
111168
view
13:35, 21 July 2020
Egonw
Made another pathway clickable
111046
view
12:27, 3 July 2020
L Dupuis
Connected lines
86905
view
08:00, 14 July 2016
Mkutmon
Ontology Term : 'inflammatory response pathway' added !
86904
view
08:00, 14 July 2016
Mkutmon
Ontology Term : 'PW:0000028' removed !
71866
view
21:23, 18 October 2013
MaintBot
Modified title
69273
view
18:39, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67131
view
10:10, 26 June 2013
Christine Chichester
Ontology Term : 'inflammatory response pathway' added !
41582
view
02:00, 2 March 2011
MaintBot
Removed redundant pathway information and comments
38655
view
12:55, 23 September 2010
FerryJagers
fixed database @ linked pathway
38652
view
12:44, 23 September 2010
FerryJagers
Linked pathway
35250
view
19:57, 11 February 2010
Thomas
added literature
34310
view
22:08, 9 December 2009
MaintBot
Automatic update of empty xrefs
33543
view
09:38, 1 December 2009
MaintBot
Removed group label
31573
view
21:59, 13 August 2009
MaintBot
Fixed text labels
30448
view
21:25, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Inflammatory Response
Pathway
WP920 (WikiPathways)
CD4
GeneProduct
450124 (Entrez Gene)
CSF1
GeneProduct
457127 (Entrez Gene)
CSF2
GeneProduct
471627 (Entrez Gene)
CSF3
GeneProduct
CXCL1
GeneProduct
740567 (Entrez Gene)
CXCL2
GeneProduct
740176 (Entrez Gene)
HLA-DRB1
GeneProduct
IFN1@
GeneProduct
IFNG
GeneProduct
449517 (Entrez Gene)
IL10
GeneProduct
469657 (Entrez Gene)
IL11
GeneProduct
736204 (Entrez Gene)
IL12
GeneProduct
IL12B
GeneProduct
471723 (Entrez Gene)
IL13
GeneProduct
449564 (Entrez Gene)
IL15
GeneProduct
737808 (Entrez Gene)
IL1A
GeneProduct
470485 (Entrez Gene)
IL1B
GeneProduct
450200 (Entrez Gene)
IL2
GeneProduct
461472 (Entrez Gene)
IL3
GeneProduct
471626 (Entrez Gene)
IL4
GeneProduct
449565 (Entrez Gene)
IL5
GeneProduct
743963 (Entrez Gene)
IL6
GeneProduct
463288 (Entrez Gene)
IL7
GeneProduct
464245 (Entrez Gene)
LOC473183
GeneProduct
473183 (Entrez Gene)
PATR-DRA
GeneProduct
462591 (Entrez Gene)
PDGFA
GeneProduct
TGFB1
GeneProduct
456060 (Entrez Gene)
TNF
GeneProduct
744399 (Entrez Gene)
TRA
GeneProduct
TRB
GeneProduct
Annotated Interactions
No annotated interactions
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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External references
DataNodes
Annotated Interactions
No annotated interactions