B cell receptor signaling pathway (Bos taurus)

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MACY->NUEndoplasmic reticulumCYCY->PMAccesion Number: NetPath 12NUCY->PMDCY->PMCY->NURecruitmentDeacetylationDCY->PMCY->PMCY->NUProteolytic cleavageERDesumoylationGolgi apparatusExtracellularCY->NUECPM->CYDEndosomeDPlasma membraneDeubiquitinationCY->PMDCY->PM(Protein-protein interaction)CY->NUDCY->NUDLigandGlycosylationMitochondriaSumoylationCY->NUDCY->PMPM->CYMethylationDDDCY->PMMolecule in the pathwayEnzyme ComplexCY->PMInhibitionDMTNU->CYAcetylationDCY->NUControlTranslocationCY->MTENCY->PMActivationDMolecular associationPhosphorylationDephosphorylationCytoplasmDAutophosphorylationReceptorReaction through unknown mechanisms/moleculesPalmitoylationARP2/3DProteins in a complex interactionCY->PMCY->PMDemethylationCY->PMCY->PMCY->PMCY->PMNU->CYUbiquitinationPMGONucleusComplexMT->CYCY->PMPIP5K1CDAPP1FCGR2BELK1RAPGEF1MAPKAPK2SYKBLNKARPC5CD79ABTKPIP4K2APLEKHA2CD79APRKCBMAP2K2BCL10LOC100138040PDK2PIK3CGCD22LOC509843LOC100138311CASP7CDK7CBLBPIP4K2BPIK3R2SH3BP2SH2B2ARPC3NFATC2CCNA2GSK3ACHUKBANK1MAPK4NFATC3PIK3R1CCND3PLCG1ATF2LOC509843PRKCDGTF2ISHC1RAPGEF1HDAC5CBLITPR2SYKPRKD1CCND2DAPP1STAT1RB1IKBKGPTK2BAKT1CYCSCSKLYNPTK2PRKCQCHUKPTPN6PLCG2CRKBTKPRKCBVAV1GRB2BAXINPP5DINPP5DCDK6TECCTNNB1HDAC5PPP3CAIGHMBRAFCREB1LOC506618NFATC1CDK4RPS6KB1PILRBSYKJUNRPS6KA1SLA2PPP3CBGAB1GAB2ITPR1RPS6RELCARD11LCKRELACRKBCL2L11CD5CD72AKT1DOK1PIP4K2BWASLCP2BLKSOS1ITKRELACTNNB1MAP2K1ACTR3NFATC3RHOASHC1BCL6MAP3K7BCAR1VAV2HCLS1PIP5K1BCD19PIP4K2CPPP3R1LAT2PTPN6RAP2APIP4K2BDUSP6RASA1PRKCDCARD11PIP5K1Acd21PIP5K1BHCLS1CASP9MAPK8CYCSARPC2PRKCEZAP70RELIKBKBGTF2IBAXGene SymbolLAT2CD81BRAGFYNRASGRP3ARPC1BLOC100138311GSK3BACTR2BCL2PLCG2DUSP4HCKDOK3IKBKBNEDD9PLEKHA1RAF1GAB1PLEKHA1NFATC2MAPK14RASGRP3PTPN6NCK1PRKCEATP2B4STAP1CCNE1LYNGRB2HNRNPKPTPN18MAP4K1CD79BLIME1MAPK3ARPC4PTPN11BLNKPIP5K1BNFKBIAPTPRCLYNCRKLCMTM3RPS6KA1LOC100138102HCLS1STAT3CDK2PLEKHA2MAPK1


Description

No description

Comments

GenMAPP notes 
NetPath 12 - B Cell Receptor Signaling pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP23(r20725) with a 85% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A; ''NetPath: a public resource of curated signal transduction pathways.''; Genome Biol, 2010 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117479view10:59, 21 May 2021EweitzModified title
115959view08:25, 22 March 2021EgonwCopied the NetPath paper into the literature list
115949view07:12, 22 March 2021EgonwModified description
89901view13:19, 6 October 2016MkutmonModified description
80807view15:26, 30 June 2015Mkutmonhomology conversion
67068view10:02, 26 June 2013Christine ChichesterOntology Term : 'B cell receptor signaling pathway' added !
63478view17:22, 10 May 2013MaintBotupdating gpml
40541view19:30, 1 March 2011MaintBotRemoved redundant pathway information and comments
35705view23:14, 12 February 2010AlexanderPico
33782view00:09, 9 December 2009MaintBotAutomatic update of empty xrefs
32499view12:48, 17 August 2009MaintBotFixed text labels
31197view19:32, 13 August 2009MaintBotFixed text labels
30594view22:13, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACTR2GeneProduct538486 (Entrez Gene)
ACTR3GeneProduct281597 (Entrez Gene)
AKT1GeneProduct280991 (Entrez Gene)
ARPC1BGeneProduct326600 (Entrez Gene)
ARPC2GeneProduct540838 (Entrez Gene)
ARPC3GeneProduct506596 (Entrez Gene)
ARPC4GeneProduct539459 (Entrez Gene)
ARPC5GeneProduct614345 (Entrez Gene)
ATF2GeneProduct509827 (Entrez Gene)
ATP2B4GeneProduct282146 (Entrez Gene)
BANK1GeneProduct616565 (Entrez Gene)
BAXGeneProduct785708 (Entrez Gene)
BCAR1GeneProduct527550 (Entrez Gene)
BCL10GeneProduct540824 (Entrez Gene)
BCL2GeneProduct281020 (Entrez Gene)
BCL2L11GeneProduct507390 (Entrez Gene)
BCL6GeneProduct539020 (Entrez Gene)
BLKGeneProduct532587 (Entrez Gene)
BLNKGeneProduct510393 (Entrez Gene)
BRAFGeneProduct536051 (Entrez Gene)
BRAGGeneProduct
BTKGeneProduct533459 (Entrez Gene)
CARD11GeneProduct515377 (Entrez Gene)
CASP7GeneProduct526279 (Entrez Gene)
CASP9GeneProduct100140945 (Entrez Gene)
CBLGeneProduct527418 (Entrez Gene)
CBLBGeneProduct525906 (Entrez Gene)
CCNA2GeneProduct281667 (Entrez Gene)
CCND2GeneProduct615414 (Entrez Gene)
CCND3GeneProduct540547 (Entrez Gene)
CCNE1GeneProduct533526 (Entrez Gene)
CD19GeneProduct517359 (Entrez Gene)
CD22GeneProduct514582 (Entrez Gene)
CD5GeneProduct280745 (Entrez Gene)
CD72GeneProduct783725 (Entrez Gene)
CD79AGeneProduct281674 (Entrez Gene)
CD79BGeneProduct
CD81GeneProduct511435 (Entrez Gene)
CDK2GeneProduct519217 (Entrez Gene)
CDK4GeneProduct510618 (Entrez Gene)
CDK6GeneProduct511754 (Entrez Gene)
CDK7GeneProduct515462 (Entrez Gene)
CHUKGeneProduct281073 (Entrez Gene)
CMTM3GeneProduct787512 (Entrez Gene)
CREB1GeneProduct281713 (Entrez Gene)
CRKGeneProduct512841 (Entrez Gene)
CRKLGeneProduct
CSKGeneProduct509246 (Entrez Gene)
CTNNB1GeneProduct539003 (Entrez Gene)
CYCSGeneProduct510767 (Entrez Gene)
DAPP1GeneProduct533156 (Entrez Gene)
DOK1GeneProduct514962 (Entrez Gene)
DOK3GeneProduct514894 (Entrez Gene)
DUSP4GeneProduct540380 (Entrez Gene)
DUSP6GeneProduct515310 (Entrez Gene)
ELK1GeneProduct786886 (Entrez Gene)
FCGR2BGeneProduct282229 (Entrez Gene)
FYNGeneProduct527263 (Entrez Gene)
GAB1GeneProduct540085 (Entrez Gene)
GAB2GeneProduct529346 (Entrez Gene)
GRB2GeneProduct535298 (Entrez Gene)
GSK3AGeneProduct536561 (Entrez Gene)
GSK3BGeneProduct790875 (Entrez Gene)
GTF2IGeneProduct534669 (Entrez Gene)
Gene SymbolGeneProduct
HCKGeneProduct280814 (Entrez Gene)
HCLS1GeneProduct508445 (Entrez Gene)
HDAC5GeneProduct504242 (Entrez Gene)
HNRNPKGeneProduct528135 (Entrez Gene)
IGHMGeneProduct404057 (Entrez Gene)
IKBKBGeneProduct281854 (Entrez Gene)
IKBKGGeneProduct281855 (Entrez Gene)
INPP5DGeneProduct507329 (Entrez Gene)
ITKGeneProduct522311 (Entrez Gene)
ITPR1GeneProduct317697 (Entrez Gene)
ITPR2GeneProduct281878 (Entrez Gene)
JUNGeneProduct280831 (Entrez Gene)
LAT2GeneProduct505016 (Entrez Gene)
LCKGeneProduct508890 (Entrez Gene)
LCP2GeneProduct513244 (Entrez Gene)
LIME1GeneProduct
LOC100138040GeneProduct100138040 (Entrez Gene)
LOC100138102GeneProduct100138102 (Entrez Gene)
LOC100138311GeneProduct100138311 (Entrez Gene)
LOC506618GeneProduct506618 (Entrez Gene)
LOC509843GeneProduct509843 (Entrez Gene)
LYNGeneProduct534996 (Entrez Gene)
MAP2K1GeneProduct533199 (Entrez Gene)
MAP2K2GeneProduct510434 (Entrez Gene)
MAP3K7GeneProduct529146 (Entrez Gene)
MAP4K1GeneProduct522002 (Entrez Gene)
MAPK1GeneProduct327672 (Entrez Gene)
MAPK14GeneProduct534492 (Entrez Gene)
MAPK3GeneProduct531391 (Entrez Gene)
MAPK4GeneProduct529183 (Entrez Gene)
MAPK8GeneProduct539941 (Entrez Gene)
MAPKAPK2GeneProduct788091 (Entrez Gene)
NCK1GeneProduct536154 (Entrez Gene)
NEDD9GeneProduct504967 (Entrez Gene)
NFATC1GeneProduct511224 (Entrez Gene)
NFATC2GeneProduct530401 (Entrez Gene)
NFATC3GeneProduct541127 (Entrez Gene)
NFKBIAGeneProduct282291 (Entrez Gene)
PDK2GeneProduct524075 (Entrez Gene)
PIK3CGGeneProduct530001 (Entrez Gene)
PIK3R1GeneProduct282307 (Entrez Gene)
PIK3R2GeneProduct282308 (Entrez Gene)
PILRBGeneProduct
PIP4K2AGeneProduct533289 (Entrez Gene)
PIP4K2BGeneProduct539211 (Entrez Gene)
PIP4K2CGeneProduct540005 (Entrez Gene)
PIP5K1AGeneProduct100125224 (Entrez Gene)
PIP5K1BGeneProduct537654 (Entrez Gene)
PIP5K1CGeneProduct508819 (Entrez Gene)
PLCG1GeneProduct281987 (Entrez Gene)
PLCG2GeneProduct281988 (Entrez Gene)
PLEKHA1GeneProduct513040 (Entrez Gene)
PLEKHA2GeneProduct530879 (Entrez Gene)
PPP3CAGeneProduct286852 (Entrez Gene)
PPP3CBGeneProduct790867 (Entrez Gene)
PPP3R1GeneProduct282321 (Entrez Gene)
PRKCBGeneProduct282325 (Entrez Gene)
PRKCDGeneProduct505708 (Entrez Gene)
PRKCEGeneProduct507041 (Entrez Gene)
PRKCQGeneProduct505901 (Entrez Gene)
PRKD1GeneProduct533270 (Entrez Gene)
PTK2GeneProduct506270 (Entrez Gene)
PTK2BGeneProduct541008 (Entrez Gene)
PTPN11GeneProduct533590 (Entrez Gene)
PTPN18GeneProduct617215 (Entrez Gene)
PTPN6GeneProduct512312 (Entrez Gene)
PTPRCGeneProduct407152 (Entrez Gene)
RAF1GeneProduct521196 (Entrez Gene)
RAP2AGeneProduct522707 (Entrez Gene)
RAPGEF1GeneProduct520454 (Entrez Gene)
RASA1GeneProduct282032 (Entrez Gene)
RASGRP3GeneProduct523745 (Entrez Gene)
RB1GeneProduct534712 (Entrez Gene)
RELGeneProduct509135 (Entrez Gene)
RELAGeneProduct508233 (Entrez Gene)
RHOAGeneProduct338049 (Entrez Gene)
RPS6GeneProduct782738 (Entrez Gene)
RPS6KA1GeneProduct533908 (Entrez Gene)
RPS6KB1GeneProduct404181 (Entrez Gene)
SH2B2GeneProduct617840 (Entrez Gene)
SH3BP2GeneProduct
SHC1GeneProduct507196 (Entrez Gene)
SLA2GeneProduct514398 (Entrez Gene)
SOS1GeneProduct537682 (Entrez Gene)
STAP1GeneProduct507296 (Entrez Gene)
STAT1GeneProduct510814 (Entrez Gene)
STAT3GeneProduct508541 (Entrez Gene)
SYKGeneProduct515515 (Entrez Gene)
TECGeneProduct504733 (Entrez Gene)
VAV1GeneProduct617345 (Entrez Gene)
VAV2GeneProduct
WASGeneProduct
ZAP70GeneProduct504509 (Entrez Gene)
cd21GeneProduct407126 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1025"