Actin cytoskeleton regulation (Bos taurus)

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Actin polymerizationPI3KGPCR+pGene ExpressionRTKFocal complexassembly?Stabilizationof actinRASPI3KAdherens junction pathwayGFGrowth Factor (GF)MAPK SignalingpathwayRTKChemotactic factorGPCR-pFocal adhesionassemblyLamellipodiaActomyosinassembly contractionFocal adhesion pathwayActin polymerizationstress fiberFilipodiaRASActin polymerizationstress fiberChemotatic factorFocal adhesion pathwayFGFR4PIP5K1CMAP2K2WASCHRM5CSKNRASFGFR1PFN1LOC442775LOC615374PPP1R12ALOC615374FGF4LOC615374FGF9MRASFGF20PIP2ARHGEF1PDGFBMSNLOC505611TMSB4XMYL3PIK3CGPAK4EGFRAC1P4RDXIQGAP1MYL1MAPK1CHRM3FGF14LOC537790PIP5K1ARHOAFGF23LOC615374ACTBFGF1FGF11LIMK1C11orf13SSH3ARHGEF6PIP4K2ARAC3PIK3CBFGF16VCLPIK3R5CDC42ARPC5ARPC5MAP2K1CRKBradykininPIK3R3APCFGF12Apc2LOC615374SLC9A1PXNABI2LOC513301PIK3R1MYH10ARHGEF7MAPK4FGF2CHRM2RRASLOC615374PIP4K2APIP3DOCK1MAPK6BAIAP2ROCK1PAK7FGF17SSH1NCKAP1PIK3CDFGF18FGFR2F2RFGF8PTK2FGF7WASF2PAK1CYFIP2FN1EZRBDKRB1MYLKGRLF1FGF6ITGA1PIP2GNG12PDGFRAGSNFGF22PIK3R2LOC100138040ACTG1KRASPik3c2bACTN1LOC785576CHRM1PDGFRBMAPK3FGF5BRAFPDGFASOS1SSH2PFN1AcetylcholinePIK3C3FGD1EGFRACTBCHRM4GNA12BAIAP2PAK2F2VIL1ACTBRAC2RAF1PAK3RAC1PIP5K1BARHGEF4PIP4K2CGIT1BDKRB2LPSMOSWASF1FGF13CFL1BCAR1CFL2FGF10PIP5KL1RRAS2ARHGEF6FGF3FGFR3PAK6VCLCD14ACTG1PIK3R4PIK3CAVAV1ACTG1ROCK2PIP4K2BENAH


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks 
Adapted from KEGG (right-click to see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r20783) with a 84% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
120933view09:05, 1 February 2022EgonwMade four pathways clickable
117595view11:36, 21 May 2021EweitzModified title
80894view15:30, 30 June 2015Mkutmonhomology conversion
72126view07:48, 25 October 2013Mkutmonadded datasource for pathway datanodes
71429view19:03, 17 October 2013MaintBotAutomated update of data sources
63458view17:18, 10 May 2013MaintBotUpdated to 2013 gpml schema
48126view05:45, 9 May 2012MaintBotUpdating from human to fix xref duplication
40593view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33830view00:28, 9 December 2009MaintBotAutomatic update of empty xrefs
32520view12:56, 17 August 2009MaintBotFixed text labels
32207view12:41, 15 August 2009MaintBotFixed text labels
31695view11:48, 14 August 2009MaintBotFixed group labels
31218view19:40, 13 August 2009MaintBotFixed text labels
30631view22:26, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct537711 (Entrez Gene)
ACTBGeneProduct280979 (Entrez Gene)
ACTG1GeneProduct404122 (Entrez Gene)
ACTN1GeneProduct524770 (Entrez Gene)
APCGeneProduct533233 (Entrez Gene)
ARHGEF1GeneProduct513377 (Entrez Gene)
ARHGEF4GeneProduct505852 (Entrez Gene)
ARHGEF6GeneProduct533823 (Entrez Gene)
ARHGEF7GeneProduct524352 (Entrez Gene)
ARPC5GeneProduct614345 (Entrez Gene)
AcetylcholineMetabolite
Apc2GeneProduct526572 (Entrez Gene)
BAIAP2GeneProduct507837 (Entrez Gene)
BCAR1GeneProduct527550 (Entrez Gene)
BDKRB1GeneProduct532119 (Entrez Gene)
BDKRB2GeneProduct538896 (Entrez Gene)
BRAFGeneProduct536051 (Entrez Gene)
BradykininMetabolite
C11orf13GeneProduct
CD14GeneProduct281048 (Entrez Gene)
CDC42GeneProduct532712 (Entrez Gene)
CFL1GeneProduct534553 (Entrez Gene)
CFL2GeneProduct539332 (Entrez Gene)
CHRM1GeneProduct281684 (Entrez Gene)
CHRM2GeneProduct522170 (Entrez Gene)
CHRM3GeneProduct281685 (Entrez Gene)
CHRM4GeneProduct512928 (Entrez Gene)
CHRM5GeneProduct281686 (Entrez Gene)
CRKGeneProduct512841 (Entrez Gene)
CSKGeneProduct509246 (Entrez Gene)
CYFIP2GeneProduct518833 (Entrez Gene)
DOCK1GeneProduct537203 (Entrez Gene)
EGFGeneProduct786061 (Entrez Gene)
EGFRGeneProduct407217 (Entrez Gene)
ENAHGeneProduct513095 (Entrez Gene)
EZRGeneProduct281574 (Entrez Gene)
F2GeneProduct280685 (Entrez Gene)
F2RGeneProduct526585 (Entrez Gene)
FGD1GeneProduct100124501 (Entrez Gene)
FGF10GeneProduct326285 (Entrez Gene)
FGF11GeneProduct613386 (Entrez Gene)
FGF12GeneProduct615823 (Entrez Gene)
FGF1GeneProduct281160 (Entrez Gene)
FGF13GeneProduct506924 (Entrez Gene)
FGF14GeneProduct
FGF16GeneProduct540758 (Entrez Gene)
FGF17GeneProduct
FGF18GeneProduct533929 (Entrez Gene)
FGF20GeneProduct539083 (Entrez Gene)
FGF22GeneProduct519657 (Entrez Gene)
FGF2GeneProduct281161 (Entrez Gene)
FGF23GeneProduct530239 (Entrez Gene)
FGF3GeneProduct618481 (Entrez Gene)
FGF4GeneProduct618474 (Entrez Gene)
FGF5GeneProduct536771 (Entrez Gene)
FGF6GeneProduct540317 (Entrez Gene)
FGF7GeneProduct616885 (Entrez Gene)
FGF8GeneProduct326284 (Entrez Gene)
FGF9GeneProduct
FGFR1GeneProduct281768 (Entrez Gene)
FGFR2GeneProduct404193 (Entrez Gene)
FGFR3GeneProduct281769 (Entrez Gene)
FGFR4GeneProduct317696 (Entrez Gene)
FN1GeneProduct280794 (Entrez Gene)
GIT1GeneProduct515088 (Entrez Gene)
GNA12GeneProduct515159 (Entrez Gene)
GNG12GeneProduct286850 (Entrez Gene)
GRLF1GeneProduct540310 (Entrez Gene)
GSNGeneProduct535077 (Entrez Gene)
IQGAP1GeneProduct532715 (Entrez Gene)
ITGA1GeneProduct535951 (Entrez Gene)
KRASGeneProduct541140 (Entrez Gene)
LIMK1GeneProduct535225 (Entrez Gene)
LOC100138040GeneProduct100138040 (Entrez Gene)
LOC442775GeneProduct
LOC505611GeneProduct505611 (Entrez Gene)
LOC513301GeneProduct513301 (Entrez Gene)
LOC537790GeneProduct537790 (Entrez Gene)
LOC615374GeneProduct615374 (Entrez Gene)
LOC785576GeneProduct785576 (Entrez Gene)
LPSMetaboliteC00338 (Kegg Compound)
MAP2K1GeneProduct533199 (Entrez Gene)
MAP2K2GeneProduct510434 (Entrez Gene)
MAPK1GeneProduct327672 (Entrez Gene)
MAPK3GeneProduct531391 (Entrez Gene)
MAPK4GeneProduct529183 (Entrez Gene)
MAPK6GeneProduct538094 (Entrez Gene)
MOSGeneProduct444869 (Entrez Gene)
MRASGeneProduct540803 (Entrez Gene)
MSNGeneProduct540426 (Entrez Gene)
MYH10GeneProduct317655 (Entrez Gene)
MYL1GeneProduct317657 (Entrez Gene)
MYL3GeneProduct618352 (Entrez Gene)
MYLKGeneProduct338037 (Entrez Gene)
NCKAP1GeneProduct787496 (Entrez Gene)
NRASGeneProduct506322 (Entrez Gene)
PAK1GeneProduct533729 (Entrez Gene)
PAK2GeneProduct
PAK3GeneProduct534526 (Entrez Gene)
PAK4GeneProduct539742 (Entrez Gene)
PAK6GeneProduct539224 (Entrez Gene)
PAK7GeneProduct513432 (Entrez Gene)
PDGFAGeneProduct505908 (Entrez Gene)
PDGFBGeneProduct540106 (Entrez Gene)
PDGFRAGeneProduct282301 (Entrez Gene)
PDGFRBGeneProduct527165 (Entrez Gene)
PFN1GeneProduct781603 (Entrez Gene)
PIK3C3GeneProduct534815 (Entrez Gene)
PIK3CAGeneProduct282306 (Entrez Gene)
PIK3CBGeneProduct517948 (Entrez Gene)
PIK3CDGeneProduct504531 (Entrez Gene)
PIK3CGGeneProduct530001 (Entrez Gene)
PIK3R1GeneProduct282307 (Entrez Gene)
PIK3R2GeneProduct282308 (Entrez Gene)
PIK3R3GeneProduct286865 (Entrez Gene)
PIK3R4GeneProduct507414 (Entrez Gene)
PIK3R5GeneProduct614838 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP4K2AGeneProduct533289 (Entrez Gene)
PIP4K2BGeneProduct539211 (Entrez Gene)
PIP4K2CGeneProduct540005 (Entrez Gene)
PIP5K1AGeneProduct100125224 (Entrez Gene)
PIP5K1BGeneProduct537654 (Entrez Gene)
PIP5K1CGeneProduct508819 (Entrez Gene)
PIP5KL1GeneProduct523736 (Entrez Gene)
PPP1R12AGeneProduct538606 (Entrez Gene)
PTK2GeneProduct506270 (Entrez Gene)
PXNGeneProduct517456 (Entrez Gene)
Pik3c2bGeneProduct537396 (Entrez Gene)
RAC1GeneProduct281440 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct327671 (Entrez Gene)
RAC3GeneProduct619066 (Entrez Gene)
RAF1GeneProduct521196 (Entrez Gene)
RDXGeneProduct517111 (Entrez Gene)
RHOAGeneProduct338049 (Entrez Gene)
ROCK1GeneProduct785911 (Entrez Gene)
ROCK2GeneProduct282041 (Entrez Gene)
RRAS2GeneProduct519269 (Entrez Gene)
RRASGeneProduct616503 (Entrez Gene)
SLC9A1GeneProduct317654 (Entrez Gene)
SOS1GeneProduct537682 (Entrez Gene)
SSH1GeneProduct538233 (Entrez Gene)
SSH2GeneProduct512652 (Entrez Gene)
SSH3GeneProduct514643 (Entrez Gene)
TMSB4XGeneProduct781334 (Entrez Gene)
VAV1GeneProduct617345 (Entrez Gene)
VCLGeneProduct783645 (Entrez Gene)
VIL1GeneProduct281573 (Entrez Gene)
WASGeneProduct
WASF1GeneProduct531488 (Entrez Gene)
WASF2GeneProduct504482 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1062"