Actin cytoskeleton regulation (Bos taurus)

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Actomyosinassembly contractionRTK+p?stress fiberActin polymerizationGFPI3KFilipodiaFocal adhesionassemblyStabilizationof actinActin polymerizationstress fiberGene ExpressionRTKGPCRLamellipodiaRASPI3KGrowth Factor (GF)Chemotatic factorFocal complexassembly-pGPCRRASChemotactic factorActin polymerizationFGF4Apc2PIP2MAPK6INS1SSH2PDGFRAMAPK1CHRM2FGFR1PIP4K2BBRAFRRASAcetylcholinePAK6CD14FGF23ACTG1FGF22PIK3R4PDGFRBFGF11BradykininARHGEF6MYL3CSKPXNPIK3CGMAPK4KRASFGF12FGF20Focal AdhesionpathwayFGF8PIK3CAPFN1RAF1Focal AdhesionpathwayPIK3C2GFGF9VCLFGF21ENAHPIK3R3PIK3C3EZRNRASFGF14LIMK1ARHGEF7ARPC5FGFR2FGF16DIAP3ROCK2PIP2VIL1DIAP1SOS2FGF2SOS1FGF1PIK3R1CHRM3PAK4F2FN1FGFR4MAPK3PIP5KL1RASSF7FGF18PIP4K2CPAK3ACTBVCLLOC100336547GSNPIK3R2FGFR3PIP5K1CPIP4K2AAdherens junctionpathwayBAIAP2FGF15FGF17GNG12ARHGEF4PDGFBPIK3R5ACTBMYH10BRK1PIK3C2AITGA1BDKRB1RRAS2FGF3MAPK SignalingpathwayF2RPDGFAFGF7MOSCHRM4MYLKRAC1ACTN1CDC42PAK2LOC442775FGF6APCBAIAP2PIP4K2ACHRM1WASF1ACTG1BCAR1CFL1MAP2K1IQGAP1ABI2MYL1BDKRB2PIK3CDMRASACTBPIP5K1BLPSCYFIP2SLC9A1PAK7RAC3ARHGAP35FGD1ROCK1PPP1R12APIP5K1AFGF5ARPC5TMSB4XEGFRRAC2PIK3C2BPAK1GNA13RHOARDXCRKGIT1PTK2EGFARHGEF6MSNMAP2K2ACTG1WASF2RAC1P4FGF13GNA12INS2NCKAP1PFN1SSH3CFL2PIK3CBDOCK1FGF10SSH1VAV1ARHGEF1PIP3CHRM5


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r45278) with a 90% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
120933view09:05, 1 February 2022EgonwMade four pathways clickable
117595view11:36, 21 May 2021EweitzModified title
80894view15:30, 30 June 2015Mkutmonhomology conversion
72126view07:48, 25 October 2013Mkutmonadded datasource for pathway datanodes
71429view19:03, 17 October 2013MaintBotAutomated update of data sources
63458view17:18, 10 May 2013MaintBotUpdated to 2013 gpml schema
48126view05:45, 9 May 2012MaintBotUpdating from human to fix xref duplication
40593view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33830view00:28, 9 December 2009MaintBotAutomatic update of empty xrefs
32520view12:56, 17 August 2009MaintBotFixed text labels
32207view12:41, 15 August 2009MaintBotFixed text labels
31695view11:48, 14 August 2009MaintBotFixed group labels
31218view19:40, 13 August 2009MaintBotFixed text labels
30631view22:26, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct537711 (Entrez Gene)
ACTBGeneProduct280979 (Entrez Gene)
ACTG1GeneProduct404122 (Entrez Gene)
ACTN1GeneProduct524770 (Entrez Gene)
APCGeneProduct533233 (Entrez Gene)
ARHGAP35GeneProduct540310 (Entrez Gene)
ARHGEF1GeneProduct513377 (Entrez Gene)
ARHGEF4GeneProduct505852 (Entrez Gene)
ARHGEF6GeneProduct533823 (Entrez Gene)
ARHGEF7GeneProduct524352 (Entrez Gene)
ARPC5GeneProduct614345 (Entrez Gene)
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct507837 (Entrez Gene)
BCAR1GeneProduct527550 (Entrez Gene)
BDKRB1GeneProduct532119 (Entrez Gene)
BDKRB2GeneProduct538896 (Entrez Gene)
BRAFGeneProduct536051 (Entrez Gene)
BRK1GeneProduct540092 (Entrez Gene)
BradykininMetabolite58-82-2 (CAS)
CD14GeneProduct281048 (Entrez Gene)
CDC42GeneProduct532712 (Entrez Gene)
CFL1GeneProduct534553 (Entrez Gene)
CFL2GeneProduct539332 (Entrez Gene)
CHRM1GeneProduct281684 (Entrez Gene)
CHRM2GeneProduct522170 (Entrez Gene)
CHRM3GeneProduct281685 (Entrez Gene)
CHRM4GeneProduct512928 (Entrez Gene)
CHRM5GeneProduct281686 (Entrez Gene)
CRKGeneProduct512841 (Entrez Gene)
CSKGeneProduct509246 (Entrez Gene)
CYFIP2GeneProduct518833 (Entrez Gene)
DIAP1GeneProduct
DIAP3GeneProduct
DOCK1GeneProduct537203 (Entrez Gene)
EGFGeneProduct530315 (Entrez Gene)
EGFRGeneProduct407217 (Entrez Gene)
ENAHGeneProduct513095 (Entrez Gene)
EZRGeneProduct281574 (Entrez Gene)
F2GeneProduct280685 (Entrez Gene)
F2RGeneProduct526585 (Entrez Gene)
FGD1GeneProduct100124501 (Entrez Gene)
FGF10GeneProduct326285 (Entrez Gene)
FGF11GeneProduct613386 (Entrez Gene)
FGF12GeneProduct
FGF1GeneProduct281160 (Entrez Gene)
FGF13GeneProduct506924 (Entrez Gene)
FGF14GeneProduct
FGF15GeneProduct
FGF16GeneProduct540758 (Entrez Gene)
FGF17GeneProduct
FGF18GeneProduct533929 (Entrez Gene)
FGF20GeneProduct539083 (Entrez Gene)
FGF21GeneProduct785576 (Entrez Gene)
FGF22GeneProduct519657 (Entrez Gene)
FGF2GeneProduct281161 (Entrez Gene)
FGF23GeneProduct530239 (Entrez Gene)
FGF3GeneProduct618481 (Entrez Gene)
FGF4GeneProduct618474 (Entrez Gene)
FGF5GeneProduct536771 (Entrez Gene)
FGF6GeneProduct540317 (Entrez Gene)
FGF7GeneProduct616885 (Entrez Gene)
FGF8GeneProduct326284 (Entrez Gene)
FGF9GeneProduct613731 (Entrez Gene)
FGFR1GeneProduct281768 (Entrez Gene)
FGFR2GeneProduct404193 (Entrez Gene)
FGFR3GeneProduct281769 (Entrez Gene)
FGFR4GeneProduct317696 (Entrez Gene)
FN1GeneProduct
Focal Adhesion pathwayPathwayWP306
GIT1GeneProduct515088 (Entrez Gene)
GNA12GeneProduct515159 (Entrez Gene)
GNA13GeneProduct505611 (Entrez Gene)
GNG12GeneProduct286850 (Entrez Gene)
GSNGeneProduct535077 (Entrez Gene)
INS1GeneProduct
INS2GeneProduct
IQGAP1GeneProduct532715 (Entrez Gene)
ITGA1GeneProduct535951 (Entrez Gene)
KRASGeneProduct541140 (Entrez Gene)
LIMK1GeneProduct535225 (Entrez Gene)
LOC100336547GeneProduct100336547 (Entrez Gene)
LOC442775GeneProduct
LPSMetaboliteC00338 (KEGG Compound)
MAP2K1GeneProduct533199 (Entrez Gene)
MAP2K2GeneProduct510434 (Entrez Gene)
MAPK Signaling pathwayPathwayWP382
MAPK1GeneProduct327672 (Entrez Gene)
MAPK3GeneProduct531391 (Entrez Gene)
MAPK4GeneProduct
MAPK6GeneProduct538094 (Entrez Gene)
MOSGeneProduct444869 (Entrez Gene)
MRASGeneProduct540803 (Entrez Gene)
MSNGeneProduct540426 (Entrez Gene)
MYH10GeneProduct317655 (Entrez Gene)
MYL1GeneProduct317657 (Entrez Gene)
MYL3GeneProduct618352 (Entrez Gene)
MYLKGeneProduct
NCKAP1GeneProduct100300817 (Entrez Gene)
NRASGeneProduct506322 (Entrez Gene)
PAK1GeneProduct533729 (Entrez Gene)
PAK2GeneProduct513673 (Entrez Gene)
PAK3GeneProduct534526 (Entrez Gene)
PAK4GeneProduct539742 (Entrez Gene)
PAK6GeneProduct539224 (Entrez Gene)
PAK7GeneProduct513432 (Entrez Gene)
PDGFAGeneProduct505908 (Entrez Gene)
PDGFBGeneProduct540106 (Entrez Gene)
PDGFRAGeneProduct282301 (Entrez Gene)
PDGFRBGeneProduct527165 (Entrez Gene)
PFN1GeneProduct513895 (Entrez Gene)
PIK3C2AGeneProduct537790 (Entrez Gene)
PIK3C2BGeneProduct537396 (Entrez Gene)
PIK3C2GGeneProduct513301 (Entrez Gene)
PIK3C3GeneProduct534815 (Entrez Gene)
PIK3CAGeneProduct282306 (Entrez Gene)
PIK3CBGeneProduct517948 (Entrez Gene)
PIK3CDGeneProduct504531 (Entrez Gene)
PIK3CGGeneProduct530001 (Entrez Gene)
PIK3R1GeneProduct282307 (Entrez Gene)
PIK3R2GeneProduct282308 (Entrez Gene)
PIK3R3GeneProduct286865 (Entrez Gene)
PIK3R4GeneProduct507414 (Entrez Gene)
PIK3R5GeneProduct614838 (Entrez Gene)
PIP2MetaboliteC04637 (KEGG Compound)
PIP3MetaboliteC05981 (KEGG Compound)
PIP4K2AGeneProduct533289 (Entrez Gene)
PIP4K2BGeneProduct539211 (Entrez Gene)
PIP4K2CGeneProduct540005 (Entrez Gene)
PIP5K1AGeneProduct100125224 (Entrez Gene)
PIP5K1BGeneProduct537654 (Entrez Gene)
PIP5K1CGeneProduct508819 (Entrez Gene)
PIP5KL1GeneProduct523736 (Entrez Gene)
PPP1R12AGeneProduct
PTK2GeneProduct506270 (Entrez Gene)
PXNGeneProduct517456 (Entrez Gene)
RAC1GeneProduct281440 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct327671 (Entrez Gene)
RAC3GeneProduct619066 (Entrez Gene)
RAF1GeneProduct521196 (Entrez Gene)
RASSF7GeneProduct538490 (Entrez Gene)
RDXGeneProduct517111 (Entrez Gene)
RHOAGeneProduct338049 (Entrez Gene)
ROCK1GeneProduct785911 (Entrez Gene)
ROCK2GeneProduct282041 (Entrez Gene)
RRAS2GeneProduct519269 (Entrez Gene)
RRASGeneProduct616503 (Entrez Gene)
SLC9A1GeneProduct317654 (Entrez Gene)
SOS1GeneProduct537682 (Entrez Gene)
SOS2GeneProduct100138040 (Entrez Gene)
SSH1GeneProduct538233 (Entrez Gene)
SSH2GeneProduct512652 (Entrez Gene)
SSH3GeneProduct514643 (Entrez Gene)
TMSB4XGeneProduct
VAV1GeneProduct617345 (Entrez Gene)
VCLGeneProduct783645 (Entrez Gene)
VIL1GeneProduct281573 (Entrez Gene)
WASF1GeneProduct531488 (Entrez Gene)
WASF2GeneProduct504482 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1062"