Thymic stromal lymphopoietin (TSLP) signaling pathway (Homo sapiens)

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MAPK9PMAP2K2PMAPK3PChemotaxis and ProteinMYCTSLPCRLF2STAT1STAT3PSTAT4PPMAPK1PPTPN11PJAK2PJAK1IL7RPMAP2K1PMAPK14PNFKBIAPRELBRELANFKB1NFKB2MAPK8PRELARELBNFKB1NFKB2TECPSTAT5ASTAT5BPPPI3KRPS6EIF4EBP1PPMTORC1AKT1PGAB2PSTAT6PPPI dissociation induced activationReceptorEnzyme family/complexmRNAProteinTransportPositive regulation of gene expressionLeads to through unknown mechanismTranslocation Induced catalysisProtein-protein interaction (PPI)LEGENDNucleusCytoplasmCYNUNUCYNUCYNUCYNUCYNUCYNUCYTSLP Signaling PathwaySRCPSTAT5BSTAT5APPLigandNUCYSTAT3TNFSF4IL8CISHIL2RAIL6CCL11survival ofeosinophilsAirway infllamatory responseDentritic cell mediatedProliferation ofTh2 responseCell proliferationAnti-apoptosisDentritic cell migrationInvasion of trophoblastsAirway infllamatory responsepre-ALL cells


Description

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
126371view17:51, 25 April 2023EgonwLicense is CCZero (more specific)
120724view01:31, 24 December 2021EweitzStandardize font, weight, case
117845view15:15, 22 May 2021EweitzModified title
105841view23:12, 15 August 2019KhanspersModified description
96065view17:58, 15 February 2018KhanspersModified description
86071view07:28, 29 June 2016MirellaKalafatiModified title
85046view09:39, 10 April 2016EgonwReplaced a mim-conversion with mim-stimulation.
78549view10:30, 7 January 2015MaintBotadded missing graphIds
77474view06:24, 15 September 2014NetPathPeriodical save, work in progress
72104view21:49, 24 October 2013AlexanderPicoadded EC number for PI3K complex
71374view18:38, 17 October 2013MaintBotAutomated update of data sources
70626view23:08, 18 August 2013MaintBotupdated gpml from NetPath
68943view17:35, 8 July 2013MaintBotUpdated to 2013 gpml schema
67728view11:55, 26 June 2013DdiglesOntology Term : 'interleukin-2 family mediated signaling pathway' added !
57845view18:21, 4 February 2013MaintBotModified categories
48521view06:58, 1 June 2012NetPathOntology Term : 'Jak-Stat signaling pathway' added !
48520view06:57, 1 June 2012NetPathOntology Term : 'cytokine mediated signaling pathway' added !
48519view06:54, 1 June 2012NetPathModified description
48518view06:51, 1 June 2012NetPathModified description
48517view06:48, 1 June 2012NetPathNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1Protein207 (Entrez Gene)
CCL11Rna6356 (Entrez Gene)
CISHRna1154 (Entrez Gene)
CRLF2Protein64109 (Entrez Gene)
EIF4EBP1Protein1978 (Entrez Gene)
GAB2Protein9846 (Entrez Gene)
IL2RARna3559 (Entrez Gene)
IL6Rna3569 (Entrez Gene)
IL7RProtein3575 (Entrez Gene)
IL8Rna3576 (Entrez Gene)
JAK1Protein3716 (Entrez Gene)
JAK2Protein3717 (Entrez Gene)
LigandProtein85480 (Entrez Gene)
MAP2K1Protein5604 (Entrez Gene)
MAP2K2Protein5605 (Entrez Gene)
MAPK14Protein1432 (Entrez Gene)
MAPK1Protein5594 (Entrez Gene)
MAPK3Protein5595 (Entrez Gene)
MAPK8Protein5599 (Entrez Gene)
MAPK9Protein5601 (Entrez Gene)
MTORProtein2475 (Entrez Gene)
MTORC1Complex
MYCRna4609 (Entrez Gene)
NFKB1Protein4790 (Entrez Gene)
NFKB2Protein4791 (Entrez Gene)
NFKBIAProtein4792 (Entrez Gene)
PI3KComplex
PIK3CAProtein5290 (Entrez Gene)
PIK42AProtein55361 (Entrez Gene)
PTPN11Protein5781 (Entrez Gene)
ProteinGeneProduct
RELAProtein5970 (Entrez Gene)
RELBProtein5971 (Entrez Gene)
RPS6Protein6194 (Entrez Gene)
SRCComplex
STAT1Protein6772 (Entrez Gene)
STAT3Protein6774 (Entrez Gene)
STAT4Protein6775 (Entrez Gene)
STAT5AProtein6776 (Entrez Gene)
STAT5BProtein6777 (Entrez Gene)
STAT6Protein6778 (Entrez Gene)
TECComplex
TNFSF4Rna7292 (Entrez Gene)
TSLPProtein85480 (Entrez Gene)

Annotated Interactions

No annotated interactions

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