Thymic stromal lymphopoietin (TSLP) signaling pathway (Homo sapiens)

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MAP2K2S226MAPK3Y204T202T207Survival and chemotaxis ofeosinophilsDissociationTSLPCRLF2STAT1Y701STAT3S727Y705STAT4Y693MAPK1T185Y187PTPN11JAK2Y542Y1008JAK1Y570Y1007Y1035Y1034IL7RMAP2K1S218S222MAPK14Y182T180NFKBIAPRELBRELANFKB1NFKB2MAPK8T183Y185RELARELBNFKB1NFKB2TECY519PI3KRPS6S236EIF4EBP1S236T70MTORC1AKT1T308S473GAB2PSTAT6Y641Thymic stromal lymphopoietin Signaling PathwaySRCY419STAT5BY699STAT5AY694CCL11Dentritic cell-mediatedTh2 responseProliferation ofpre-ALL cellsCell proliferationAnti-apoptosisDentritic cell migrationInvasion of trophoblastsAirway inflammatory responseSTAT5BY699STAT5AY694STAT3S727Y705MAPK9T183Y185MYCIL8IL2RAIL6CISHTNFSF4NUCYNUCYNUCYNUCYNUCYNUCYNUCYYES1LCKY426BTKY394Y551FESY713HCKT412Y411FYNLYNY420Y397Cell proliferationAirway inflammatory response


Description

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Bibliography

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History

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CompareRevisionActionTimeUserComment
126371view17:51, 25 April 2023EgonwLicense is CCZero (more specific)
120724view01:31, 24 December 2021EweitzStandardize font, weight, case
117845view15:15, 22 May 2021EweitzModified title
105841view23:12, 15 August 2019KhanspersModified description
96065view17:58, 15 February 2018KhanspersModified description
86071view07:28, 29 June 2016MirellaKalafatiModified title
85046view09:39, 10 April 2016EgonwReplaced a mim-conversion with mim-stimulation.
78549view10:30, 7 January 2015MaintBotadded missing graphIds
77474view06:24, 15 September 2014NetPathPeriodical save, work in progress
72104view21:49, 24 October 2013AlexanderPicoadded EC number for PI3K complex
71374view18:38, 17 October 2013MaintBotAutomated update of data sources
70626view23:08, 18 August 2013MaintBotupdated gpml from NetPath
68943view17:35, 8 July 2013MaintBotUpdated to 2013 gpml schema
67728view11:55, 26 June 2013DdiglesOntology Term : 'interleukin-2 family mediated signaling pathway' added !
57845view18:21, 4 February 2013MaintBotModified categories
48521view06:58, 1 June 2012NetPathOntology Term : 'Jak-Stat signaling pathway' added !
48520view06:57, 1 June 2012NetPathOntology Term : 'cytokine mediated signaling pathway' added !
48519view06:54, 1 June 2012NetPathModified description
48518view06:51, 1 June 2012NetPathModified description
48517view06:48, 1 June 2012NetPathNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1Protein207 (Entrez Gene)
BTKProtein695 (Entrez Gene)
CCL11Rna6356 (Entrez Gene)
CISHRna1154 (Entrez Gene)
CRLF2Protein64109 (Entrez Gene)
EIF4EBP1Protein1978 (Entrez Gene)
FESProtein2242 (Entrez Gene)
FYNProtein2534 (Entrez Gene)
GAB2Protein9846 (Entrez Gene)
HCKProtein3055 (Entrez Gene)
IL2RARna3559 (Entrez Gene)
IL6Rna3569 (Entrez Gene)
IL7RProtein3575 (Entrez Gene)
IL8Rna3576 (Entrez Gene)
JAK1Protein3716 (Entrez Gene)
JAK2Protein3717 (Entrez Gene)
LCKProtein3932 (Entrez Gene)
LYNProtein4067 (Entrez Gene)
MAP2K1Protein5604 (Entrez Gene)
MAP2K2Protein5605 (Entrez Gene)
MAPK14Protein1432 (Entrez Gene)
MAPK1Protein5594 (Entrez Gene)
MAPK3Protein5595 (Entrez Gene)
MAPK8Protein5599 (Entrez Gene)
MAPK9Protein5601 (Entrez Gene)
MTORProtein2475 (Entrez Gene)
MTORC1Complex2475 (Entrez Gene)
MYCRna4609 (Entrez Gene)
NFKB1Protein4790 (Entrez Gene)
NFKB2Protein4791 (Entrez Gene)
NFKBIAProtein4792 (Entrez Gene)
PI3KComplex2.7.1.153 (Enzyme Nomenclature)
PIK3CAProtein5290 (Entrez Gene)
PIK42AProtein55361 (Entrez Gene)
PTPN11Protein5781 (Entrez Gene)
RELAProtein5970 (Entrez Gene)
RELBProtein5971 (Entrez Gene)
RPS6Protein6194 (Entrez Gene)
SRCProtein6714 (Entrez Gene)
STAT1Protein6772 (Entrez Gene)
STAT3Protein6774 (Entrez Gene)
STAT4Protein6775 (Entrez Gene)
STAT5AProtein6776 (Entrez Gene)
STAT5BProtein6777 (Entrez Gene)
STAT6Protein6778 (Entrez Gene)
TECProtein7006 (Entrez Gene)
TNFSF4Rna7292 (Entrez Gene)
TSLPProtein85480 (Entrez Gene)
YES1Protein7525 (Entrez Gene)

Annotated Interactions

No annotated interactions

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