Brain-derived neurotrophic factor (BDNF) signaling pathway (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

No bibliography

History

View all...

Compare	Revision	Action	Time	User	Comment
	126377	view	17:55, 25 April 2023	Egonw	License is CCZero (more specific)
	120727	view	01:41, 24 December 2021	Eweitz	Standardize font, weight, case
	116399	view	00:01, 7 May 2021	Eweitz	Modified title
	106345	view	21:34, 21 August 2019	Khanspers	Modified description
	106165	view	12:06, 16 August 2019	MaintBot	HMDB identifier normalization
	105546	view	06:09, 9 August 2019	Khanspers	Modified description
	94178	view	13:37, 25 August 2017	Mkutmon	added missing metabolite identifiers
	89803	view	11:37, 6 October 2016	Mkutmon	fixed special characters in description
	87427	view	11:51, 22 July 2016	Mkutmon	Modified description
	86036	view	12:36, 28 June 2016	Evelo	Modified title
	79953	view	11:49, 28 April 2015	Zari	Annotated IP3 and IKK
	79265	view	20:25, 19 March 2015	Zari	Chenged Identifier for NFC1
	71549	view	19:25, 17 October 2013	MaintBot	removed data source from nodes without identifier
	71001	view	15:55, 22 September 2013	Egonw	Added three metabolite IDs.
	67076	view	10:03, 26 June 2013	Christine Chichester	Ontology Term : 'brain-derived neurotrophic factor signaling pathway' added !
	61289	view	21:55, 6 April 2013	MaintBot	removed old publication references
	61232	view	17:23, 5 April 2013	MaintBot	updated pathway elements from provided gpml
	61042	view	04:48, 3 April 2013	NetPath	Modified description
	60957	view	10:30, 1 April 2013	NetPath	Periodical save, work in progress
	54595	view	18:45, 4 December 2012	MaintBot	Modified categories
	54573	view	07:11, 4 December 2012	NetPath	Modified description
	54552	view	13:14, 3 December 2012	NetPath	New pathway

External references

DataNodes

View all...

Name	Type	Database reference	Comment
ACACB	Protein	32 (Entrez Gene)
ADAM17	Protein	6868 (Entrez Gene)
AKT1	Protein	207 (Entrez Gene)
ALPL	Rna	249 (Entrez Gene)
APC	Protein	324 (Entrez Gene)
BAD	Protein	572 (Entrez Gene)
BCL2L11	Rna	10018 (Entrez Gene)
BDNF	Protein	627 (Entrez Gene)
BMP2	Rna	650 (Entrez Gene)
CAMK1	Protein	8536 (Entrez Gene)
CAMK2	Protein	815 (Entrez Gene)
CAMK4	Protein	814 (Entrez Gene)
CASP3	Protein	836 (Entrez Gene)
CDC42	Protein	998 (Entrez Gene)
CDH2	Protein	1000 (Entrez Gene)
CDK5	Protein	1020 (Entrez Gene)
CDK5R1	Protein	8851 (Entrez Gene)
CDKL5	Protein	6792 (Entrez Gene)
CEBPB	Protein	1385 (Entrez Gene)
CFL1	Protein	1072 (Entrez Gene)
CNR1	Protein	1268 (Entrez Gene)
CREB1	Protein	1385 (Entrez Gene)
CRTC1	Protein	23373 (Entrez Gene)
CSNK2A1	Protein	1457 (Entrez Gene)
CTNNB1	Protein	1499 (Entrez Gene)
CYFIP1	GeneProduct	23191 (Entrez Gene)
DAG	Metabolite
DLG1	Protein	1739 (Entrez Gene)
DOCK3	Protein	1795 (Entrez Gene)
DOK5	Protein	55816 (Entrez Gene)
DPYSL2	Protein	1808 (Entrez Gene)
EEF2	Protein	1938 (Entrez Gene)
EGR1	Rna	1958 (Entrez Gene)
EGR2	Rna	1959 (Entrez Gene)
EIF2S1	Protein	1965 (Entrez Gene)
EIF2S2	Protein	8894 (Entrez Gene)
EIF4E	Protein	1977 (Entrez Gene)
EIF4EBP1	Protein	1978 (Entrez Gene)
ELK1	Protein	2002 (Entrez Gene)
FOS	Rna	2353 (Entrez Gene)
FOXO3	Protein	2309 (Entrez Gene)
FRS2	Protein	10818 (Entrez Gene)
FRS3	Protein	10817 (Entrez Gene)
FYN	Protein	2534 (Entrez Gene)
GABRB3	Protein	2562 (Entrez Gene)
GNB2L1	Protein	10399 (Entrez Gene)
GRB2	Protein	2885 (Entrez Gene)
GRIA1	Protein	2890 (Entrez Gene)
GRIA2	Protein	2891 (Entrez Gene)
GRIA3	Protein	2892 (Entrez Gene)
GRIN1	Protein	2902 (Entrez Gene)
GRIN2B	Protein	2904 (Entrez Gene)
GRIP1	Protein	23426 (Entrez Gene)
GSK3B	Protein	2932 (Entrez Gene)
HRAS	Protein	3265 (Entrez Gene)
IGF2BP1	Protein	10642 (Entrez Gene)
IKK	Protein
IP3	Protein
IRS1	Protein	3667 (Entrez Gene)
IRS2	Protein	8660 (Entrez Gene)
JAK2	Protein	3717 (Entrez Gene)
JUN	Protein	3725 (Entrez Gene)
KCNA3	Protein	3738 (Entrez Gene)
KCNN2	Protein	3781 (Entrez Gene)
KIDINS220	Protein	57498 (Entrez Gene)
KSR1	Protein	8844 (Entrez Gene)
LINGO1	Protein	84894 (Entrez Gene)
MAP2K1	Protein	5604 (Entrez Gene)
MAP2K2	Protein	5605 (Entrez Gene)
MAP2K5	Protein	5607 (Entrez Gene)
MAP3K1	Protein	4214 (Entrez Gene)
MAP3K2	Protein	10746 (Entrez Gene)
MAPK10	Protein	5602 (Entrez Gene)
MAPK14	Protein	1432 (Entrez Gene)
MAPK1	Protein	5594 (Entrez Gene)
MAPK3	Protein	5595 (Entrez Gene)
MAPK7	Protein	5598 (Entrez Gene)
MAPK8	Protein	5599 (Entrez Gene)
MAPK9	Protein	5601 (Entrez Gene)
MAPT	Protein	4137 (Entrez Gene)
MARCKS	Protein	4082 (Entrez Gene)
MEF2A	Protein	4205 (Entrez Gene)
MEF2C	Protein	4208 (Entrez Gene)
MTOR	Protein	2475 (Entrez Gene)
NCAM1	Protein	4684 (Entrez Gene)
NCF1	Protein	4687 (Entrez Gene)
NCF2	Protein	4688 (Entrez Gene)
NCK1	Protein	4690 (Entrez Gene)
NCK2	Protein	8440 (Entrez Gene)
NFATC4	Protein	4776 (Entrez Gene)
NFKB1	Protein	4790 (Entrez Gene)
NFKBIA	Protein	4792 (Entrez Gene)
NGF	Protein	4803 (Entrez Gene)
NGFR	Protein	4804 (Entrez Gene)
NSF	Protein	4905 (Entrez Gene)
NTF3	Protein	4908 (Entrez Gene)
NTRK1	Protein	4914 (Entrez Gene)
NTRK2	Protein	4915 (Entrez Gene)
NTRK3	Protein	4916 (Entrez Gene)
PDPK1	Protein	5170 (Entrez Gene)
PIK3CA	Protein	5296 (Entrez Gene)
PIK3R1	Protein	5295 (Entrez Gene)
PIK3R2	Protein	5296 (Entrez Gene)
PIP2	Metabolite
PIP3	Metabolite
PLCG1	Protein	5335 (Entrez Gene)
PPP2CA	Protein	5515 (Entrez Gene)
PRKAA1	Protein	5562 (Entrez Gene)
PRKAA2	Protein	5563 (Entrez Gene)
PRKCD	Protein	5580 (Entrez Gene)
PTK2B	Protein	2185 (Entrez Gene)
PTPN11	Protein	5781 (Entrez Gene)
PTPRF	Protein	5792 (Entrez Gene)
RAB3A	Protein	5864 (Entrez Gene)
RAC1	Protein	5879 (Entrez Gene)
RAF1	Protein	5894 (Entrez Gene)
RANBP9	Protein	10048 (Entrez Gene)
RAP1A	Protein	5906 (Entrez Gene)
RASGRF1	Protein	5923 (Entrez Gene)
RELA	Protein	5970 (Entrez Gene)
RHOG	Protein	391 (Entrez Gene)
RPS6	Protein	6194 (Entrez Gene)
RPS6KA1	Protein	6195 (Entrez Gene)
RPS6KA3	Protein	6197 (Entrez Gene)
RPS6KA5	Protein	9252 (Entrez Gene)
RPS6KB1	Protein	6198 (Entrez Gene)
SH2B2	Protein	10603 (Entrez Gene)
SH2B	Protein	25970 (Entrez Gene)
SHC1	Protein	6464 (Entrez Gene)
SHC2	Protein	25759 (Entrez Gene)
SHC3	Protein	53358 (Entrez Gene)
SHC4	Protein	399694 (Entrez Gene)
SIRPA	Protein	140885 (Entrez Gene)
SORT1	Protein	6272 (Entrez Gene)
SPP1	Rna	6696 (Entrez Gene)
SQSTM1	Protein	8878 (Entrez Gene)
SRC	Protein	6714 (Entrez Gene)
STAT1	Protein	6772 (Entrez Gene)
STAT3	Protein	6774 (Entrez Gene)
STAT5A	Protein	6776 (Entrez Gene)
STAT5B	Protein	6777 (Entrez Gene)
SYN1	Protein	6853 (Entrez Gene)
TIAM1	Protein	7074 (Entrez Gene)
TRAF6	Protein	7189 (Entrez Gene)
TSC2	Protein	7249 (Entrez Gene)
VAV2	Protein	7410 (Entrez Gene)
VAV3	Protein	10451 (Entrez Gene)
YBX1	Protein	4904 (Entrez Gene)
cAMP	Metabolite

Annotated Interactions

No annotated interactions