Nutrient control of ribosomal gene expression (Saccharomyces cerevisiae)

From WikiPathways

Revision as of 20:57, 12 January 2015 by Stacia (Talk | contribs)
Jump to: navigation, search
Transcription of5S RNA genestRNA genesActiveCrf1prepressorYak1pkinaseTpk3pkinaseFhl1pregulatorSch9pkinaseSfp1pTFRNA Pol ITorC1complexRNA Pol IIAmino acidpermeasesGpr1preceptoramino acidscAMPCyr1padenylatecyclaseTpk1pkinaseRrn3pTFD-GlucoseMaf1pregulatorTpk2pkinaseIfh1pactivatorRNA Pol IIISch9pkinaseamino acidsMaf1pregulatorMaf1pregulatorActiveSfp1pTFRrn3pTFTorC1complexCrf1prepressorActiveActiveActiveActivecytosolnucleusTranscription ofribosomal protein genesribosome biogenesis genesTranscription ofrDNA genes


Description

No description

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Mager WH, Planta RJ; ''Multifunctional DNA-binding proteins mediate concerted transcription activation of yeast ribosomal protein genes.''; Biochim Biophys Acta, 1990 PubMed Europe PMC Scholia
  2. Li B, Nierras CR, Warner JR; ''Transcriptional elements involved in the repression of ribosomal protein synthesis.''; Mol Cell Biol, 1999 PubMed Europe PMC Scholia
  3. Yamamoto RT, Nogi Y, Dodd JA, Nomura M; ''RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template.''; EMBO J, 1996 PubMed Europe PMC Scholia
  4. Fath S, Milkereit P, Peyroche G, Riva M, Carles C, Tschochner H; ''Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.''; Proc Natl Acad Sci U S A, 2001 PubMed Europe PMC Scholia
  5. Moir RD, Lee J, Willis IM; ''Recovery of RNA polymerase III transcription from the glycerol-repressed state: revisiting the role of protein kinase CK2 in Maf1 phosphoregulation.''; J Biol Chem, 2012 PubMed Europe PMC Scholia
  6. Mager WH, Planta RJ, Ballesta JG, Lee JC, Mizuta K, Suzuki K, Warner JR, Woolford J; ''A new nomenclature for the cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.''; Nucleic Acids Res, 1997 PubMed Europe PMC Scholia
  7. Huber A, Bodenmiller B, Uotila A, Stahl M, Wanka S, Gerrits B, Aebersold R, Loewith R; ''Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.''; Genes Dev, 2009 PubMed Europe PMC Scholia
  8. Philippi A, Steinbauer R, Reiter A, Fath S, Leger-Silvestre I, Milkereit P, Griesenbeck J, Tschochner H; ''TOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA production.''; Nucleic Acids Res, 2010 PubMed Europe PMC Scholia
  9. Zhao Y, McIntosh KB, Rudra D, Schawalder S, Shore D, Warner JR; ''Fine-structure analysis of ribosomal protein gene transcription.''; Mol Cell Biol, 2006 PubMed Europe PMC Scholia
  10. Rudra D, Warner JR; ''What better measure than ribosome synthesis?''; Genes Dev, 2004 PubMed Europe PMC Scholia
  11. Moir RD, Lee J, Haeusler RA, Desai N, Engelke DR, Willis IM; ''Protein kinase A regulates RNA polymerase III transcription through the nuclear localization of Maf1.''; Proc Natl Acad Sci U S A, 2006 PubMed Europe PMC Scholia
  12. Claypool JA, French SL, Johzuka K, Eliason K, Vu L, Dodd JA, Beyer AL, Nomura M; ''Tor pathway regulates Rrn3p-dependent recruitment of yeast RNA polymerase I to the promoter but does not participate in alteration of the number of active genes.''; Mol Biol Cell, 2004 PubMed Europe PMC Scholia
  13. Goetze H, Wittner M, Hamperl S, Hondele M, Merz K, Stoeckl U, Griesenbeck J; ''Alternative chromatin structures of the 35S rRNA genes in Saccharomyces cerevisiae provide a molecular basis for the selective recruitment of RNA polymerases I and II.''; Mol Cell Biol, 2010 PubMed Europe PMC Scholia
  14. Zhao Y, Sohn JH, Warner JR; ''Autoregulation in the biosynthesis of ribosomes.''; Mol Cell Biol, 2003 PubMed Europe PMC Scholia
  15. Gerber J, Reiter A, Steinbauer R, Jakob S, Kuhn CD, Cramer P, Griesenbeck J, Milkereit P, Tschochner H; ''Site specific phosphorylation of yeast RNA polymerase I.''; Nucleic Acids Res, 2008 PubMed Europe PMC Scholia
  16. Conrad M, Schothorst J, Kankipati HN, Van Zeebroeck G, Rubio-Texeira M, Thevelein JM; ''Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae.''; FEMS Microbiol Rev, 2014 PubMed Europe PMC Scholia
  17. Graczyk D, Debski J, Muszyńska G, Bretner M, Lefebvre O, Boguta M; ''Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation.''; Proc Natl Acad Sci U S A, 2011 PubMed Europe PMC Scholia
  18. Verschoor A, Warner JR, Srivastava S, Grassucci RA, Frank J; ''Three-dimensional structure of the yeast ribosome.''; Nucleic Acids Res, 1998 PubMed Europe PMC Scholia
  19. Lee J, Moir RD, Willis IM; ''Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway.''; J Biol Chem, 2009 PubMed Europe PMC Scholia
  20. Zaman S, Lippman SI, Zhao X, Broach JR; ''How Saccharomyces responds to nutrients.''; Annu Rev Genet, 2008 PubMed Europe PMC Scholia
  21. Venema J, Tollervey D; ''Ribosome synthesis in Saccharomyces cerevisiae.''; Annu Rev Genet, 1999 PubMed Europe PMC Scholia
  22. Jenner L, Melnikov S, Garreau de Loubresse N, Ben-Shem A, Iskakova M, Urzhumtsev A, Meskauskas A, Dinman J, Yusupova G, Yusupov M; ''Crystal structure of the 80S yeast ribosome.''; Curr Opin Struct Biol, 2012 PubMed Europe PMC Scholia
  23. Lempiäinen H, Shore D; ''Growth control and ribosome biogenesis.''; Curr Opin Cell Biol, 2009 PubMed Europe PMC Scholia
  24. Warner JR; ''The economics of ribosome biosynthesis in yeast.''; Trends Biochem Sci, 1999 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
110881view14:30, 17 June 2020EgonwReplaced an IntAct complex identifier with a Complex Portal identifier (the link out redirects to Complex Portal anyway)
107254view14:35, 17 September 2019MaintBotChEBI identifier normalization
107017view13:47, 17 September 2019MaintBotHMDB identifier normalization
89882view12:58, 6 October 2016MkutmonModified description
78912view20:25, 12 February 2015StaciaSpecify description
78870view18:33, 10 February 2015StaciaSpecify description
78762view13:12, 23 January 2015Bart SmeetsConnected all unconnected lines.
78761view13:08, 23 January 2015Bart SmeetsSpecify description
78760view13:07, 23 January 2015Bart SmeetsPeriodical save, work in progress
78759view12:57, 23 January 2015Bart SmeetsPeriodical save, work in progress
78703view18:04, 15 January 2015StaciaModified description
78702view17:54, 15 January 2015StaciaModified description
78688view05:56, 14 January 2015StaciaSpecify description
78687view05:51, 14 January 2015StaciaModified description
78686view05:32, 14 January 2015StaciaSpecify description
78685view05:29, 14 January 2015StaciaSpecify description
78678view00:35, 14 January 2015StaciaModified description
78677view00:34, 14 January 2015StaciaSpecify description
78676view00:32, 14 January 2015StaciaModified description
78675view00:00, 14 January 2015StaciaSpecify description
78674view23:53, 13 January 2015StaciaSpecify description
78673view23:50, 13 January 2015StaciaSpecify description
78672view23:23, 13 January 2015StaciaSpecify description
78669view00:04, 13 January 2015StaciaModified description
78668view00:04, 13 January 2015StaciaSpecify description
78667view00:03, 13 January 2015StaciaModified description
78666view23:54, 12 January 2015StaciaSpecify description
78665view23:50, 12 January 2015StaciaModified description
78664view23:16, 12 January 2015StaciaOntology Term : 'regulatory pathway' added !
78663view23:16, 12 January 2015StaciaOntology Term : 'signaling pathway' added !
78662view23:12, 12 January 2015StaciaSpecify description
78659view21:09, 12 January 2015StaciaSpecify description
78658view21:08, 12 January 2015StaciaSpecify description
78657view21:05, 12 January 2015StaciaSpecify description
78656view21:02, 12 January 2015StaciaSpecify description
78655view20:59, 12 January 2015StaciaSpecify description
78654view20:57, 12 January 2015StaciaSpecify description
78653view20:56, 12 January 2015StaciaSpecify description
78652view20:53, 12 January 2015StaciaPeriodical save, work in progress
78651view20:52, 12 January 2015StaciaSpecify description
78650view20:50, 12 January 2015StaciaSpecify description
78649view20:50, 12 January 2015StaciaSpecify description
78648view20:50, 12 January 2015StaciaSpecify description
78647view20:46, 12 January 2015StaciaSpecify description
78646view20:46, 12 January 2015StaciaSpecify description
78645view20:45, 12 January 2015StaciaSpecify description
78644view20:43, 12 January 2015StaciaSpecify description
78643view20:43, 12 January 2015StaciaPeriodical save, work in progress
78642view20:41, 12 January 2015StaciaSpecify description
78641view20:34, 12 January 2015StaciaSpecify description

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Amino acid permeases
Crf1p repressorProteinS000002631 (SGD)
Cyr1p

adenylate

cyclase		ProteinS000003542 (SGD)
D-GlucoseMetaboliteHMDB00122 (HMDB)
Fhl1p regulatorProteinS000006308 (SGD)
Gpr1p receptorProteinS000002193 (SGD)
Ifh1p activatorProteinS000004213 (SGD)
Maf1p regulatorProteinS000002412 (SGD)
RNA Pol IComplexEBI-2339149 (IntAct)
RNA Pol IIIComplexS000005642 (SGD)
RNA Pol IIComplexS000002299 (SGD)
Rrn3p TFProteinS000001608 (SGD)
Sch9p kinaseProteinS000001248 (SGD)
Sfp1p TFProteinS000004395 (SGD)
TorC1 complexComplexEBI-2435049 (IntAct)
Tpk1p kinaseProteinS000003700 (SGD)
Tpk2p kinaseProteinS000006124 (SGD)
Tpk3p kinaseProteinS000001649 (SGD)
Yak1p kinaseProteinS000003677 (SGD)
amino acidsMetabolite33709 (ChEBI)
cAMPMetaboliteHMDB00058 (HMDB)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2869"