T cell receptor signaling pathway (Rattus norvegicus)

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Reaction through unknown mechanisms/moleculesLigandDDemethylationNUMethylationMolecular associationPMAutophosphorylationNU->CYAcetylationAccession Number: NetPath_11Endoplasmic reticulumGOPalmitoylationUbiquitinationGlycosylationDeubiquitinationMolecule in the pathwayActivationDephosphorylationRecruitmentProteolytic cleavageSumoylationNucleusExtracellularCytoplasmEndosomeECGene SymbolControlInhibitionCY->NUERDesumoylationENPhosphorylationDGolgi apparatusProteins in a complex interactionCY->PMTranslocationAntigenMT(Protein-protein interaction)Plasma membraneMitochondrionCY->NUDeacetylationEnzyme complexReceptorCYStk39Rac2Lax1Cd3eMap4k1Stat5aJunYWHAQDef6CblbGab2PtprhArhgef7Wipf1Mapk1PAG1Cd247BrafSHBPpp3cbItpr1Ripk2Muc1LatPtpn6Abl1CDC42Ptk2CebpbDusp3Zap70Git2Creb1DTX1DbnlSlaSh3bp2MAPK7GrapPtk2bItkShc1Dnm2Ptpn12Nfam1Tuba4aLynCd2Map3k1LckStat5bRasgrp2Sh2d2aCblTubb5RAPGEF1PxnCd2apPtpn3Skap1Cd8aSkap2VaspFosCd3dCrebbpDock2EnahHomer3Ctnnb1FynPrkd2Rasa1SykPlcg1Vav2Fcrl3Nfatc2TRB@Nedd9Cd4Vav3Sh2d3cTxkPik3r1Unc119JunAkt1Jak3EvlRap1aGrb2Map2k2Ptpn11Stat1Pstpip1CARD11Pak1CrkHdac7ArhgdibKhdrbs1Hdac7Cd3gSos1Acp1Mapk3Lcp2Cd3ePrkcqPik3r2Trat1Lime1TRA@Cd5FybCd247CrklWasf2PtprjAbi1Map2k1Stat5aSOS2Vav1Grap2Lcp2RGD1562071Lime1PtprcNcl-ps1Dlg1LNKStat5bNck1FybNck1Sit1Bcl10Cabin1SrcCishPtpn22Arhgef6WAS


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 91% conversion rate.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
118026view11:42, 23 May 2021EweitzModified title
69416view19:02, 8 July 2013MaintBotUpdated to 2013 gpml schema
67681view11:48, 26 June 2013DdiglesOntology Term : 'T cell receptor signaling pathway' added !
41739view02:39, 2 March 2011MaintBotRemoved redundant pathway information and comments
34112view19:24, 9 December 2009MaintBotAutomatic update of empty xrefs
31437view21:04, 13 August 2009MaintBotFixed text labels
30958view00:45, 30 July 2009MaintBotConverted from Homo sapiens
21417view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:T-Cell-Receptor NetPath 11]] moved to [[Pathway:WP352]]: Moved to stable identifier
8430view13:46, 7 January 2008MaintBot[[Pathway:Rat:T-Cell-Receptor NetPath 11]] moved to [[Pathway:Rattus norvegicus:T-Cell-Receptor NetPath 11]]: Renaming species
7832view16:21, 18 December 2007MaintBotfixed category names
7300view12:42, 4 November 2007MaintBotAdded categories to GPML
6600view22:20, 22 May 2007A.Pandeygpml file for [[Rat:T-Cell-Receptor_NetPath_11]]

External references

DataNodes

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NameTypeDatabase referenceComment
Abi1GeneProduct79249 (Entrez Gene)
Abl1GeneProduct311860 (Entrez Gene)
Acp1GeneProduct24161 (Entrez Gene)
Akt1GeneProduct24185 (Entrez Gene)
ArhgdibGeneProduct362456 (Entrez Gene)
Arhgef6GeneProduct363509 (Entrez Gene)
Arhgef7GeneProduct114559 (Entrez Gene)
Bcl10GeneProduct83477 (Entrez Gene)
BrafGeneProduct114486 (Entrez Gene)
CARD11GeneProduct304314 (Entrez Gene)
CDC42GeneProduct64465 (Entrez Gene)
Cabin1GeneProduct94165 (Entrez Gene)
CblGeneProduct500985 (Entrez Gene)
CblbGeneProduct171136 (Entrez Gene)
Cd247GeneProduct25300 (Entrez Gene)
Cd2GeneProduct497761 (Entrez Gene)
Cd2apGeneProduct316258 (Entrez Gene)
Cd3dGeneProduct25710 (Entrez Gene)
Cd3eGeneProduct315609 (Entrez Gene)
Cd3gGeneProduct300678 (Entrez Gene)
Cd4GeneProduct24932 (Entrez Gene)
Cd5GeneProduct54236 (Entrez Gene)
Cd8aGeneProduct24930 (Entrez Gene)
CebpbGeneProduct24253 (Entrez Gene)
CishGeneProduct83681 (Entrez Gene)
Creb1GeneProduct81646 (Entrez Gene)
CrebbpGeneProduct54244 (Entrez Gene)
CrkGeneProduct54245 (Entrez Gene)
CrklGeneProduct287942 (Entrez Gene)
Ctnnb1GeneProduct84353 (Entrez Gene)
DTX1GeneProduct
DbnlGeneProduct83527 (Entrez Gene)
Def6GeneProduct309642 (Entrez Gene)
Dlg1GeneProduct25252 (Entrez Gene)
Dnm2GeneProduct25751 (Entrez Gene)
Dock2GeneProduct360509 (Entrez Gene)
Dusp3GeneProduct498003 (Entrez Gene)
EnahGeneProduct360891 (Entrez Gene)
EvlGeneProduct79115 (Entrez Gene)
Fcrl3GeneProduct680697 (Entrez Gene)
FosGeneProduct314322 (Entrez Gene)
FybGeneProduct499537 (Entrez Gene)
FynGeneProduct25150 (Entrez Gene)
Gab2GeneProduct84477 (Entrez Gene)
Git2GeneProduct304546 (Entrez Gene)
Grap2GeneProduct366962 (Entrez Gene)
GrapGeneProduct363616 (Entrez Gene)
Grb2GeneProduct81504 (Entrez Gene)
Hdac7GeneProduct84582 (Entrez Gene)
Homer3GeneProduct29548 (Entrez Gene)
ItkGeneProduct363577 (Entrez Gene)
Itpr1GeneProduct25262 (Entrez Gene)
Jak3GeneProduct25326 (Entrez Gene)
JunGeneProduct24516 (Entrez Gene)
Khdrbs1GeneProduct117268 (Entrez Gene)
LNKGeneProduct
LatGeneProduct81511 (Entrez Gene)
Lax1GeneProduct498232 (Entrez Gene)
LckGeneProduct313050 (Entrez Gene)
Lcp2GeneProduct155918 (Entrez Gene)
Lime1GeneProduct362289 (Entrez Gene)
LynGeneProduct81515 (Entrez Gene)
MAPK7GeneProduct114509 (Entrez Gene)
Map2k1GeneProduct170851 (Entrez Gene)
Map2k2GeneProduct58960 (Entrez Gene)
Map3k1GeneProduct116667 (Entrez Gene)
Map4k1GeneProduct292763 (Entrez Gene)
Mapk1GeneProduct116590 (Entrez Gene)
Mapk3GeneProduct50689 (Entrez Gene)
Muc1GeneProduct24571 (Entrez Gene)
Nck1GeneProduct300955 (Entrez Gene)
Ncl-ps1GeneProduct64556 (Entrez Gene)
Nedd9GeneProduct291044 (Entrez Gene)
Nfam1GeneProduct362966 (Entrez Gene)
Nfatc2GeneProduct311658 (Entrez Gene)
PAG1GeneProduct
Pak1GeneProduct29431 (Entrez Gene)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct29741 (Entrez Gene)
Plcg1GeneProduct25738 (Entrez Gene)
Ppp3cbGeneProduct24675 (Entrez Gene)
PrkcqGeneProduct85420 (Entrez Gene)
Prkd2GeneProduct292658 (Entrez Gene)
Pstpip1GeneProduct300732 (Entrez Gene)
Ptk2GeneProduct25614 (Entrez Gene)
Ptk2bGeneProduct50646 (Entrez Gene)
Ptpn11GeneProduct25622 (Entrez Gene)
Ptpn12GeneProduct117255 (Entrez Gene)
Ptpn22GeneProduct295338 (Entrez Gene)
Ptpn3GeneProduct362524 (Entrez Gene)
Ptpn6GeneProduct116689 (Entrez Gene)
PtprcGeneProduct24699 (Entrez Gene)
PtprhGeneProduct171125 (Entrez Gene)
PtprjGeneProduct29645 (Entrez Gene)
PxnGeneProduct360820 (Entrez Gene)
RAPGEF1GeneProduct63881 (Entrez Gene)
RGD1562071GeneProduct499931 (Entrez Gene)
Rac2GeneProduct366957 (Entrez Gene)
Rap1aGeneProduct295347 (Entrez Gene)
Rasa1GeneProduct25676 (Entrez Gene)
Rasgrp2GeneProduct361714 (Entrez Gene)
Ripk2GeneProduct362491 (Entrez Gene)
SHBGeneProduct
SOS2GeneProduct85384 (Entrez Gene)
Sh2d2aGeneProduct310688 (Entrez Gene)
Sh2d3cGeneProduct362111 (Entrez Gene)
Sh3bp2GeneProduct305450 (Entrez Gene)
Shc1GeneProduct85385 (Entrez Gene)
Sit1GeneProduct500449 (Entrez Gene)
Skap1GeneProduct286975 (Entrez Gene)
Skap2GeneProduct155183 (Entrez Gene)
SlaGeneProduct338477 (Entrez Gene)
Sos1GeneProduct313845 (Entrez Gene)
SrcGeneProduct83805 (Entrez Gene)
Stat1GeneProduct25124 (Entrez Gene)
Stat5aGeneProduct24918 (Entrez Gene)
Stat5bGeneProduct25126 (Entrez Gene)
Stk39GeneProduct54348 (Entrez Gene)
SykGeneProduct25155 (Entrez Gene)
TRA@GeneProduct
TRB@GeneProduct
Trat1GeneProduct498075 (Entrez Gene)
Tuba4aGeneProduct316531 (Entrez Gene)
Tubb5GeneProduct29214 (Entrez Gene)
TxkGeneProduct305311 (Entrez Gene)
Unc119GeneProduct29402 (Entrez Gene)
VaspGeneProduct361517 (Entrez Gene)
Vav1GeneProduct25156 (Entrez Gene)
Vav2GeneProduct296603 (Entrez Gene)
Vav3GeneProduct295378 (Entrez Gene)
WASGeneProduct317371 (Entrez Gene)
Wasf2GeneProduct313024 (Entrez Gene)
Wipf1GeneProduct117538 (Entrez Gene)
YWHAQGeneProduct25577 (Entrez Gene)
Zap70GeneProduct301348 (Entrez Gene)

Annotated Interactions

No annotated interactions
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