ATM signaling in development and disease (Homo sapiens)

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1Hypotonic Stress DNA Damage AutophagyOxidative StressV(D)JCSRCDKp38MAPKATMINCEP63Reactive Oxygen Species CTIPNEMORNF20PP2ALamin-BRNF168uH2BLKB1Cdc25RNF40Mre11XLFCHK2PP5G6PDCell CycleATF2TSC2Bub1SMC1Nbs1HSP27MDC1NF-KBHMGN1TIP60HMGN1WIP1uH2AATRATMAMPKArtemis53BP1CHK1RNF8H2AXRad50Aurora BDNAPKcsKAP1p38RIF1mTORC1ATMATMATMMre11Rad50Nbs1ATMNbs1Mre11Rad50ATMATM


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Stracker TH, Roig I, Knobel PA, Marjanović M; ''The ATM signaling network in development and disease.''; Front Genet, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
128977view18:05, 26 February 2024Khanspersclarify connection to checkpoint activation
128958view14:50, 25 February 2024EgonwFixed a datasource
128600view02:05, 15 February 2024EweitzTweak placement
128599view02:04, 15 February 2024EweitzTuck straggling node
128598view02:01, 15 February 2024EweitzEconomize layout, standardize case
127927view19:35, 17 January 2024Khanspersupdated xrefs, lables
127911view07:10, 13 January 2024Khanspersupdated and xrefs and cleaned up pathway nodes
127910view06:34, 13 January 2024Khanspersupdated xrefs
123399view06:26, 23 July 2022EgonwMade a pathway clickable
117656view11:51, 22 May 2021EweitzModified title
106756view13:23, 17 September 2019MaintBotHMDB identifier normalization
105871view04:47, 16 August 2019KhanspersModified description
105432view04:33, 8 August 2019KhanspersModified description
89745view23:52, 29 September 2016KhanspersModified title
89623view19:41, 21 September 2016Khanspersupdated labels, some xrefs, added legend and coloring
88965view22:23, 17 August 2016AAR&CoModified description
88964view22:20, 17 August 2016AAR&CoModified description
88962view22:15, 17 August 2016AAR&CoModified description
88856view15:59, 16 August 2016AAR&CoModified description
88849view22:17, 15 August 2016AAR&CoOntology Term : 'G1 phase pathway' added !
88848view22:16, 15 August 2016AAR&CoOntology Term : 'DNA repair pathway' added !
88847view22:15, 15 August 2016AAR&CoAdded Literature Reference
88846view22:13, 15 August 2016AAR&CoNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
53BP1GeneProductENSG00000067369 (Ensembl)
AMPKGeneProductENSG00000132356 (Ensembl)
ATF2GeneProductENSG00000115966 (Ensembl)
ATMGeneProductENSG00000149311 (Ensembl)
ATMINGeneProductENSG00000166454 (Ensembl)
ATRGeneProductENSG00000175054 (Ensembl)
ArtemisGeneProductENSG00000152457 (Ensembl)
Aurora BGeneProductENSG00000178999 (Ensembl)
Bub1GeneProductENSG00000169679 (Ensembl)
CDKGeneProductENSG00000170312 (Ensembl)
CEP63GeneProductENSG00000182923 (Ensembl)
CHK1GeneProductENSG00000149554 (Ensembl)
CHK2GeneProductENSG00000183765 (Ensembl)
CTIPGeneProductENSG00000101773 (Ensembl)
Cdc25GeneProductENSG00000058335 (Ensembl)
Cell CyclePathwayWP45 (WikiPathways)
DNAPKcsGeneProductENSG00000253729 (Ensembl)
G6PDGeneProductENSG00000160211 (Ensembl)
H2AXGeneProductENSG00000188486 (Ensembl)
HMGN1GeneProductENSG00000205581 (Ensembl)
HSP27GeneProductENSG00000106211 (Ensembl)
KAP1GeneProductENSG00000130726 (Ensembl)
LKB1GeneProductENSG00000118046 (Ensembl)
Lamin-BGeneProductENSG00000143815 (Ensembl)
MDC1GeneProductENSG00000137337 (Ensembl)
Mre11GeneProductENSG00000242537 (Ensembl)
NEMOGeneProductENSG00000269335 (Ensembl)
NF-KBGeneProductENSG00000109320 (Ensembl)
Nbs1GeneProductENSG00000104320 (Ensembl)
PP2AGeneProductENSG00000113575 (Ensembl)
PP5GeneProductENSG00000011485 (Ensembl)
RIF1GeneProductENSG00000080345 (Ensembl)
RNF168GeneProductENSG00000163961 (Ensembl)
RNF20GeneProductENSG00000155827 (Ensembl)
RNF40GeneProductENSG00000103549 (Ensembl)
RNF8GeneProductENSG00000112130 (Ensembl)
Rad50GeneProductENSG00000113522 (Ensembl)
Reactive Oxygen Species MetaboliteHMDB03125 (HMDB)
SMC1GeneProductENSG00000072501 (Ensembl)
TIP60GeneProductENSG00000172977 (Ensembl)
TSC2GeneProductENSG00000103197 (Ensembl)
WIP1GeneProductENSG00000170836 (Ensembl)
XLFGeneProductENSG00000152457 (Ensembl)
mTORC1GeneProductENSG00000198793 (Ensembl)
p38GeneProductENSG00000176749 (Ensembl)
p38MAPKGeneProductENSG00000197442 (Ensembl)
uH2AGeneProductIdentifier not Found
uH2BGeneProductIdentifier not Found

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3878"