Development of pulmonary dendritic cells and macrophage subsets (Homo sapiens)

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1HSCCMPMDPcMoPLy6C-hiMonocytesCDPPre-cDCPre-cDCPre-cDCPre-cDC2Pre-pDCpDCpDCPre-cDC1Pre-cDC1Pre-cDC1MDP: Monocyte-macrophage DC progenitorPathways found in independent studiesCDP: Common DC progenitorCMP: Common myeloid progenitorHSC: Hematopoietic stem cellscMoP: Common monocyte progenitorcDC: Conventional DCYolksacFetalliverID2IRF4RUNX2FLT3LIkarosSTAT3IRF8CSF2PU.1TPOPU.1IRF8CSF1CSF1FLT3LPU.1CSF1STAT3FLT3LPU.1STAT3PU.1E2-2FLT3LFLT3LCSF1IRF8BATF3Pre-cDC2Pre-cDC2Ly6C-loMonocytesLy6C-hiMonocytesLy6C-hiMonocytesLy6C-loMonocytesLy6C-loMonocytesCSF1CD103+ DCIRF8BATF3CD11b+ DCFLT3LIRF4CSF1CSF2CD103+Monocyte-derived DCMonocyte-derivedmacrophageCD11b+ Monocyte-derivedmacrophageLy6C-loMonocytesLy6C-loMonocytesAlveolarmacrophageLungInterstitialmacrophageBloodBone MarrowPathways found in single study / controversialDC: Dendritic cellspDC: Plasmacytoid DC


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Hoffmann F, Ender F, Schmudde I, Lewkowich IP, Köhl J, König P, Laumonnier Y; ''Origin, Localization, and Immunoregulatory Properties of Pulmonary Phagocytes in Allergic Asthma.''; Front Immunol, 2016 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
129336view09:10, 27 March 2024MkutmonOntology Term : 'regulatory pathway' added !
129221view02:09, 16 March 2024EweitzOntology Term : 'hematopoietic stem cell' added !
129220view02:08, 16 March 2024EweitzOntology Term : 'common dendritic progenitor' added !
129219view02:07, 16 March 2024EweitzOntology Term : 'common myeloid progenitor' added !
129218view02:06, 16 March 2024EweitzOntology Term : 'plasmacytoid dendritic cell, human' added !
129217view02:06, 16 March 2024EweitzOntology Term : 'plasmacytoid dendritic cell' added !
120069view18:43, 27 October 2021Khanspersupdated interactions to graphical lines
106387view21:24, 28 August 2019KhanspersModified description
105569view06:26, 9 August 2019KhanspersModified description
89703view20:56, 26 September 2016KhanspersConnected interaction
89699view19:16, 26 September 2016Khanspersincreased cell label font size
89698view19:08, 26 September 2016Khanspersupdated colors for readability
89319view15:45, 1 September 2016KhanspersOntology Term : 'bone marrow hematopoietic cell' added !
89318view15:44, 1 September 2016KhanspersOntology Term : 'dendritic cell' added !
89317view15:44, 1 September 2016KhanspersOntology Term : 'macrophage dendritic cell progenitor' added !
89316view15:43, 1 September 2016KhanspersModified description
89314view15:40, 1 September 2016KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
BATF3GeneProductENSG00000123685 (Ensembl)
CSF1GeneProductENSG00000184371 (Ensembl)
CSF2GeneProductENSG00000164400 (Ensembl)
E2-2GeneProductENSG00000196628 (Ensembl)
FLT3LGeneProductENSG00000090554 (Ensembl)
ID2GeneProductENSG00000115738 (Ensembl)
IRF4GeneProductENSG00000137265 (Ensembl)
IRF8GeneProductENSG00000140968 (Ensembl)
IkarosGeneProductENSG00000185811 (Ensembl)
PU.1GeneProductENSG00000066336 (Ensembl)
RUNX2GeneProductENSG00000124813 (Ensembl)
STAT3GeneProductENSG00000168610 (Ensembl)
TPOGeneProductENSG00000115705 (Ensembl)

Annotated Interactions

No annotated interactions

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