Fatty acid biosynthesis (Rattus norvegicus)

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Mitochondrion6 iterationsless than 6 iterationsAcyl-CoA (n+2)Fasnbeta-hydroxybutyrylAcacaPalmityl-CoAFasnEchdc3Butyryl-CoAEchdc13-L-Hydroxyacyl-CoAScd1Acetyl-ACPFasnAcas2Acsl1FasnAcetoacetyl-ACPHadhscOxalacetic acidAcsl6Ech1Palmitic acidEchs1Triacylglyceride SynthesisFatty acid CoAEchdc2AcacbTCA CycleAcsl3Acetyl-CoADecr1Acsl5Pyruvic acidCrotonoyl-CoAMecrMalonyl-CoAAcaa2AclyAcetyl-synthasetrans-delta2-enoyl-CoAFasnMalonyl-ACPFasnPecrFasnAcsl4PcLong-Chain fatty acidFasnCitric acid3-ketoacyl-CoA


Description

The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.

Comments

GenMAPP notes 
Updated from Kam Dahlquist€™s original by Magali Jaillard, Marijke Vermeer, Michiel Adrieans, Ron Schormans and Chris Evelo
GenMAPP remarks 
http://www.bigcat.unimaas.nl/mapps/

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
125345view19:40, 3 February 2023AlexanderPicoremoved old genmapp comments
125344view19:38, 3 February 2023AlexanderPicoModified description
116962view10:09, 16 May 2021EweitzModified title
113955view06:22, 11 December 2020EgonwAnother clickable pathway
106996view13:45, 17 September 2019MaintBotHMDB identifier normalization
86164view08:38, 3 July 2016EgonwFixed a typo.
83031view02:39, 18 November 2015Mkutmonfix outdated identifiers and improved layout
70134view20:37, 12 July 2013MaintBotSpecify description
70133view20:37, 12 July 2013MaintBotPeriodical save, work in progress
70132view20:27, 12 July 2013MaintBotPeriodical save, work in progress
70131view20:17, 12 July 2013MaintBot
70130view20:16, 12 July 2013MaintBotupdated to 2013 schema
67241view10:25, 26 June 2013Christine ChichesterOntology Term : 'fatty acid biosynthetic pathway' added !
60202view15:21, 14 March 2013SusanAdd meta id
60201view14:59, 14 March 2013SusanSpecify description
41767view02:41, 2 March 2011MaintBotRemoved redundant pathway information and comments
34136view19:31, 9 December 2009MaintBotAutomatic update of empty xrefs
21738view11:32, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Fatty Acid Synthesis BiGCaT]] moved to [[Pathway:WP504]]: Moved to stable identifier
15839view15:44, 5 June 2008ThomasModified categories
15691view03:38, 1 June 2008ZhouyfReverted to version '22:20, 22 May 2007' by Zhouyf
8056view13:46, 7 January 2008MaintBot[[Pathway:Rat:Fatty Acid Synthesis BiGCaT]] moved to [[Pathway:Rattus norvegicus:Fatty Acid Synthesis BiGCaT]]: Renaming species
7650view16:07, 18 December 2007MaintBotfixed category names
7359view12:42, 4 November 2007MaintBotAdded categories to GPML
19462view22:20, 22 May 2007Evelogpml file for [[Rat:Fatty_Acid_Synthesis_BiGCaT]]
6541view22:20, 22 May 2007Kdahlquistgpml file for [[Rat:Fatty_Acid_Synthesis_BiGCaT]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
3-L-Hydroxyacyl-CoAMetabolite
3-ketoacyl-CoAMetabolite
Acaa2GeneProduct170465 (Entrez Gene)
AcacaGeneProductENSRNOG00000034013 (Ensembl)
AcacbGeneProduct116719 (Entrez Gene)
Acas2GeneProduct311569 (Entrez Gene)
Acetoacetyl-ACP Metabolite
Acetyl-ACPMetabolite
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
Acetyl-synthaseMetabolite
AclyGeneProduct24159 (Entrez Gene)
Acsl1GeneProduct25288 (Entrez Gene)
Acsl3GeneProduct114024 (Entrez Gene)
Acsl4GeneProduct113976 (Entrez Gene)
Acsl5GeneProduct94340 (Entrez Gene)
Acsl6GeneProduct117243 (Entrez Gene)
Acyl-CoA (n+2)Metabolite
Butyryl-CoAMetaboliteHMDB0001088 (HMDB)
Citric acidMetaboliteHMDB0000094 (HMDB)
Crotonoyl-CoAMetaboliteHMDB0002009 (HMDB)
Decr1GeneProduct117543 (Entrez Gene)
Ech1GeneProduct51798 (Entrez Gene)
Echdc1GeneProduct361465 (Entrez Gene)
Echdc2GeneProduct298381 (Entrez Gene)
Echdc3GeneProductENSRNOG00000048114 (Ensembl)
Echs1GeneProduct140547 (Entrez Gene)
FasnGeneProduct50671 (Entrez Gene)
Fatty acid CoAMetabolite
HadhscGeneProduct113965 (Entrez Gene)
Long-Chain fatty acidMetabolite
Malonyl-ACPMetabolite
Malonyl-CoAMetaboliteHMDB0001175 (HMDB)
MecrGeneProduct29470 (Entrez Gene)
Oxalacetic acidMetaboliteHMDB0000223 (HMDB)
Palmitic acidMetaboliteHMDB0000220 (HMDB)
Palmityl-CoAMetaboliteHMDB0001338 (HMDB)
PcGeneProduct25104 (Entrez Gene)
PecrGeneProduct113956 (Entrez Gene)
Pyruvic acidMetaboliteHMDB0000243 (HMDB)
Scd1GeneProduct246074 (Entrez Gene)
TCA CyclePathwayWP347 (WikiPathways)
Triacylglyceride SynthesisPathwayWP356 (WikiPathways)
beta-hydroxybutyrylMetabolite644065 (PubChem-compound)
trans-delta2-enoyl-CoAMetabolite

Annotated Interactions

No annotated interactions
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