Non-classical role of vitamin D (Homo sapiens)

Revision as of 10:55, 30 September 2021 by Susan (Talk | contribs)

Description

Non classical role of vitamin D3

View approved pathways at the new wikipathways.org.

Malek Mahdavi A; ''A brief review of interplay between vitamin D and angiotensin-converting enzyme 2: Implications for a potential treatment for COVID-19.''; Rev Med Virol, 2020 PubMed Europe PMC Scholia
Berridge MJ; ''Vitamin D deficiency and diabetes.''; Biochem J, 2017 PubMed Europe PMC Scholia
McLachlan CS; ''The angiotensin-converting enzyme 2 (ACE2) receptor in the prevention and treatment of COVID-19 are distinctly different paradigms.''; Clin Hypertens, 2020 PubMed Europe PMC Scholia
Pérez-Hernández N, Aptilon-Duque G, Nostroza-Hernández MC, Vargas-Alarcón G, Rodríguez-Pérez JM, Blachman-Braun R; ''Vitamin D and its effects on cardiovascular diseases: a comprehensive review.''; Korean J Intern Med, 2016 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
124643	view	12:59, 18 November 2022	NhungP	Adjust layout to improve readability
121511	view	03:29, 20 February 2022	Eweitz	Modified title
120956	view	10:17, 3 February 2022	Egonw	Modified description
120955	view	10:14, 3 February 2022	Egonw	Made six pathways clickable
120233	view	11:29, 17 November 2021	Eweitz	Modified title
120115	view	14:02, 4 November 2021	HumeraFiaz	Changes in references
120114	view	14:00, 4 November 2021	HumeraFiaz	Changes in bibliography
120113	view	13:54, 4 November 2021	HumeraFiaz	Updated some graphical elements and added bibliography.
120105	view	15:11, 3 November 2021	HumeraFiaz	Modified description
120104	view	15:07, 3 November 2021	HumeraFiaz	Ontology Term : 'diabetes mellitus' added !
120103	view	14:51, 3 November 2021	HumeraFiaz	Modified description
120095	view	12:12, 2 November 2021	Susan	Ontology Term : 'hypertension' added !
119959	view	10:56, 30 September 2021	Susan	Ontology Term : 'COVID-19' added !
119958	view	10:55, 30 September 2021	Susan	Ontology Term : 'vitamin D signaling pathway' added !
119957	view	10:55, 30 September 2021	Susan	Ontology Term : 'vitamin D metabolic pathway' added !
119949	view	17:31, 28 September 2021	HumeraFiaz	New pathway

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Name	Type	Database reference
1,25-dihydroxycholecalciferol	Metabolite	CHEBI:17823 (ChEBI)
1-alpha- hydroxylase	Protein	V9GYP0 (Uniprot-TrEMBL)
25-hydroxycholecalciferol	Metabolite	CHEBI:17933 (ChEBI)
25-hydroxylase	Protein	E9PS56 (Uniprot-TrEMBL)
7-Dehydrocholesterol	Metabolite	CHEBI:17759 (ChEBI)
ACE2	Protein	Q9BYF1 (Uniprot-TrEMBL)
ACE	Protein	A0A0A0MSN4 (Uniprot-TrEMBL)
Angiotensin II	Metabolite	HMDB01035 (HMDB)
Angiotensinogen	Protein	P01019 (Uniprot-TrEMBL)
Apoptosis	Pathway	WP254 (WikiPathways)
Cholecalciferol	Metabolite	CHEBI:28940 (ChEBI)
Fibrosis	Pathway	WP3624 (WikiPathways)
Inflammation	Pathway	WP4479 (WikiPathways)
ROS production	Pathway	WP4969 (WikiPathways)
Renal Type-1 angiotensin II receptor	Protein	P30556 (Uniprot-TrEMBL)
Renin	Protein	P00797 (Uniprot-TrEMBL)
Type-1 angiotensin II receptor	Protein	P30556 (Uniprot-TrEMBL)
Type-2 angiotensin II receptor	Protein	P50052 (Uniprot-TrEMBL)
Vasodilation	Pathway	WP4580 (WikiPathways)
aldosterone	Metabolite	Q184564 (Wikidata)
angiotensin I	Metabolite	CHEBI:2718 (ChEBI)
cytokines and inflammation	Pathway	WP530 (WikiPathways)
vitamin D receptor agonists	Metabolite	CHEBI:139503 (ChEBI)

No annotated interactions