Lung pathology of COVID-19 (Homo sapiens)

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1111111111Interferon 2Interleukin-6CXCL10CXCL11IFIH1interleukin 8CXCL9IL-18TNFNFKB1IRF3MAVSDDX58IL-1betaCSF2TLR7Interferon 1TLR8CGASAirway epithelial cellTLR3Cell DeathCCL2TMEM173TBK1IRF3NFKB1


Description

Beginning of a pathway on the Lung Pathology of COVID-19 based on a figure in a paper (Reference 1)

Comments

 
This pathway is based on figure 4 of Ref 1

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Quality Tags

Ontology Terms

 

Bibliography

  1. Harrison AG, Lin T, Wang P; ''Mechanisms of SARS-CoV-2 Transmission and Pathogenesis.''; Trends Immunol, 2020 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
128308view22:10, 30 January 2024EweitzOntology Term : 'epithelial cell' added !
128307view14:39, 30 January 2024Mkutmonchanged text to labels
120619view23:32, 18 December 2021EweitzLabel group of genes
120618view17:59, 18 December 2021EweitzRemove "Golgi" label due to WP-PathVisio graphics issue
120617view17:57, 18 December 2021EweitzFix WP-PathVisio graphics issue; label organelles, virus
120616view13:08, 18 December 2021EweitzUse official gene symbol, STING1
120615view13:04, 18 December 2021EweitzTighten graphics, refine datanodes, case
120379view23:48, 29 November 2021EweitzOntology Term : 'COVID-19' added !
120378view23:47, 29 November 2021EweitzModified title
120328view16:04, 26 November 2021XNautsNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Airway epithelial cell
CCL2GeneProductENSG00000108691 (Ensembl)
CGASGeneProductENSG00000164430 (Ensembl)
CSF2GeneProductENSG00000164400 (Ensembl)
CXCL10GeneProductENSG00000169245 (Ensembl)
CXCL11GeneProductENSG00000169248 (Ensembl)
CXCL9GeneProductENSG00000138755 (Ensembl)
Cell Death
DDX58GeneProductENSG00000107201 (Ensembl)
IFIH1GeneProductENSG00000115267 (Ensembl)
IL-18ProteinENSG00000150782 (Ensembl)
IL-1betaGeneProductENSG00000125538 (Ensembl)
IRF3GeneProductENSG00000126456 (Ensembl)
Interferon 1PF00143 (Pfam)
Interferon 2PF00714 (Pfam)
Interleukin-6ProteinB4DNV3 (Uniprot-TrEMBL)
MAVSGeneProductENSG00000088888 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
TBK1GeneProductENSG00000183735 (Ensembl)
TLR3GeneProductENSG00000164342 (Ensembl)
TLR7GeneProductENSG00000196664 (Ensembl)
TLR8GeneProductENSG00000101916 (Ensembl)
TMEM173GeneProductENSG00000184584 (Ensembl)
TNFGeneProductENSG00000232810 (Ensembl)
interleukin 8MetaboliteCHEBI:138181 (ChEBI)

Annotated Interactions

No annotated interactions
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