Cholesterol metabolism (Homo sapiens)
From WikiPathways
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<Comment Source="WikiPathways-description">This pathway includes the following processes regarding cholesterol metabolism: I) Absorption of cholesterol in the enterocyte, II) Forming of chylomicrons and other lipid droplets, III) Distinction between Bloch and Kandutsch-Russell cholesterol biosynthesis, IV) Absorption of cholesterol in the hepatocyte and V) Transintestinal cholesterol excretion (TICE).</Comment> | <Comment Source="WikiPathways-description">This pathway includes the following processes regarding cholesterol metabolism: I) Absorption of cholesterol in the enterocyte, II) Forming of chylomicrons and other lipid droplets, III) Distinction between Bloch and Kandutsch-Russell cholesterol biosynthesis, IV) Absorption of cholesterol in the hepatocyte and V) Transintestinal cholesterol excretion (TICE).</Comment> | ||
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<Label TextLabel="Primary bile acid biosynthesis" GraphId="b1f5f"> | <Label TextLabel="Primary bile acid biosynthesis" GraphId="b1f5f"> | ||
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| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="996.2125262787836" CenterY="823.2255189615632" Width="375.57494744243286" Height="120.9037312319791" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="996.2125262787836" CenterY="823.2255189615632" Width="375.57494744243286" Height="120.9037312319791" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Hepatocyte" GraphId="ab671"> | <Shape TextLabel="Hepatocyte" GraphId="ab671"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
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</Shape> | </Shape> | ||
<Shape TextLabel="Golgi apparatus" GraphId="bd68c"> | <Shape TextLabel="Golgi apparatus" GraphId="bd68c"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="544.0597826086987" CenterY="918.4473061159663" Width="452.18478260868983" Height="240.17391304347848" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="544.0597826086987" CenterY="918.4473061159663" Width="452.18478260868983" Height="240.17391304347848" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Endoplasmic reticulum" GraphId="c90f8"> | <Shape TextLabel="Endoplasmic reticulum" GraphId="c90f8"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
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</Shape> | </Shape> | ||
<Shape TextLabel="Endoplasmic reticulum" GraphId="cdf79"> | <Shape TextLabel="Endoplasmic reticulum" GraphId="cdf79"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
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</Shape> | </Shape> | ||
<Shape TextLabel="Lipid droplets" GraphId="d4803"> | <Shape TextLabel="Lipid droplets" GraphId="d4803"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Vesicle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Vesicle"/> |
| - | <Graphics CenterX="1529.6703113467752" CenterY="2421.494801507711" Width="197.0441958624342" Height="121.72030200649334" ZOrder="16384" FontSize="12" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="1529.6703113467752" CenterY="2421.494801507711" Width="197.0441958624342" Height="121.72030200649334" ZOrder="16384" FontSize="12" Valign="Middle" ShapeType="Oval" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Mitochondrion" GraphId="da470"> | <Shape TextLabel="Mitochondrion" GraphId="da470"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
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</Shape> | </Shape> | ||
<Shape TextLabel="Peripheral tissue" GraphId="ee82d"> | <Shape TextLabel="Peripheral tissue" GraphId="ee82d"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
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</Shape> | </Shape> | ||
<Shape TextLabel="Endoplasmic reticulum" GraphId="ee934"> | <Shape TextLabel="Endoplasmic reticulum" GraphId="ee934"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="1848.727125" CenterY="674.895375" Width="1287.2789999999998" Height="731.6189999999999" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="1848.727125" CenterY="674.895375" Width="1287.2789999999998" Height="731.6189999999999" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Lysosome" GraphId="f17e4"> | <Shape TextLabel="Lysosome" GraphId="f17e4"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="1597.8756039573582" CenterY="1893.5627611118048" Width="1454.574737326481" Height="535.951400853314" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="1597.8756039573582" CenterY="1893.5627611118048" Width="1454.574737326481" Height="535.951400853314" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Endosome" GraphId="f4bd7"> | <Shape TextLabel="Endosome" GraphId="f4bd7"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="2814.496826305316" CenterY="1761.6345487568929" Width="737.2504185527329" Height="264.86596191176454" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="2814.496826305316" CenterY="1761.6345487568929" Width="737.2504185527329" Height="264.86596191176454" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Intestinal lumen" GraphId="fd3e0"> | <Shape TextLabel="Intestinal lumen" GraphId="fd3e0"> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Extracellular region" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Extracellular region"/> |
| - | <Graphics CenterX="584.7108749999995" CenterY="126.75993749999999" Width="1159.7197500000007" Height="160.90987499999997" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineStyle="Broken" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="584.7108749999995" CenterY="126.75993749999999" Width="1159.7197500000007" Height="160.90987499999997" ZOrder="16384" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineStyle="Broken" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Enterocyte" GraphId="affc6"> | <Shape TextLabel="Enterocyte" GraphId="affc6"> | ||
<BiopaxRef>c1d</BiopaxRef> | <BiopaxRef>c1d</BiopaxRef> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="1255.1726585234978" CenterY="674.7360583395014" Width="2497.540432953004" Height="758.7263320343868" ZOrder="32846" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0" /> | + | <Graphics CenterX="1255.1726585234978" CenterY="674.7360583395014" Width="2497.540432953004" Height="758.7263320343868" ZOrder="32846" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.0"/> |
</Shape> | </Shape> | ||
<Shape TextLabel="Endoplasmic reticulum" GraphId="e677c"> | <Shape TextLabel="Endoplasmic reticulum" GraphId="e677c"> | ||
| Line 3,734: | Line 3,734: | ||
<BiopaxRef>e3a</BiopaxRef> | <BiopaxRef>e3a</BiopaxRef> | ||
<BiopaxRef>d63</BiopaxRef> | <BiopaxRef>d63</BiopaxRef> | ||
| - | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle" /> | + | <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Organelle"/> |
| - | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" /> | + | <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/> |
| - | <Graphics CenterX="2213.960790671823" CenterY="3141.2661033408463" Width="2969.119430044402" Height="718.48524493529" ZOrder="33034" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.00877379177164725" /> | + | <Graphics CenterX="2213.960790671823" CenterY="3141.2661033408463" Width="2969.119430044402" Height="718.48524493529" ZOrder="33034" FontSize="24" Valign="Middle" ShapeType="RoundedRectangle" LineThickness="3.0" Color="c0c0c0" Rotation="0.00877379177164725"/> |
</Shape> | </Shape> | ||
| - | <Group GroupId="c1db4" Style="Complex" /> | + | <Group GroupId="c1db4" Style="Complex"/> |
| - | <Group GroupId="f5621" GraphId="a2d92" Style="Complex" /> | + | <Group GroupId="f5621" GraphId="a2d92" Style="Complex"/> |
<Group GroupId="faa37" GraphId="a6ba2" Style="Complex"> | <Group GroupId="faa37" GraphId="a6ba2" Style="Complex"> | ||
<BiopaxRef>d35</BiopaxRef> | <BiopaxRef>d35</BiopaxRef> | ||
</Group> | </Group> | ||
| - | <Group GroupId="afb7d" GraphId="adfc7" Style="Complex" /> | + | <Group GroupId="afb7d" GraphId="adfc7" Style="Complex"/> |
| - | <Group GroupId="c1ddc" GraphId="b0d0c" Style="Complex" /> | + | <Group GroupId="c1ddc" GraphId="b0d0c" Style="Complex"/> |
| - | <Group GroupId="eea6c" GraphId="b1cdd" Style="Complex" /> | + | <Group GroupId="eea6c" GraphId="b1cdd" Style="Complex"/> |
| - | <Group GroupId="dc33e" GraphId="b3205" Style="Complex" /> | + | <Group GroupId="dc33e" GraphId="b3205" Style="Complex"/> |
| - | <Group GroupId="aac46" GraphId="b5c60" Style="Complex" /> | + | <Group GroupId="aac46" GraphId="b5c60" Style="Complex"/> |
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| - | <Group GroupId="c3875" GraphId="bb102" Style="Complex" /> | + | <Group GroupId="c3875" GraphId="bb102" Style="Complex"/> |
| - | <Group GroupId="e4ffb" GraphId="bd433" Style="Complex" /> | + | <Group GroupId="e4ffb" GraphId="bd433" Style="Complex"/> |
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| - | <Group GroupId="d694a" GraphId="c0136" Style="Complex" /> | + | <Group GroupId="d694a" GraphId="c0136" Style="Complex"/> |
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| - | <Group GroupId="e06fb" GraphId="c7481" Style="Complex" /> | + | <Group GroupId="e06fb" GraphId="c7481" Style="Complex"/> |
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| - | <Group GroupId="f04af" GraphId="d1a9a" Style="Complex" /> | + | <Group GroupId="f04af" GraphId="d1a9a" Style="Complex"/> |
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| - | <Group GroupId="b02c4" GraphId="d7d1b" Style="Complex" /> | + | <Group GroupId="b02c4" GraphId="d7d1b" Style="Complex"/> |
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| - | <InfoBox CenterX="0.0" CenterY="0.0" /> | + | <InfoBox CenterX="0.0" CenterY="0.0"/> |
<Biopax> | <Biopax> | ||
<bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> | <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> | ||
| Line 3,927: | Line 3,927: | ||
<bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> | <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> | ||
</bp:openControlledVocabulary> | </bp:openControlledVocabulary> | ||
| - | </Biopax> | + | <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>hepatocyte</bp:TERM><bp:ID>CL:0000182</bp:ID><bp:Ontology>Cell Type</bp:Ontology></bp:openControlledVocabulary></Biopax> |
</Pathway> | </Pathway> | ||
Revision as of 03:31, 24 April 2024
Error rendering pathway page
This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.
Pathway history
View all... |
Error details
exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/b/be/WP5304_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
at org.pathvisio.core.Engine.importPathway(Unknown Source)
at org.pathvisio.core.util.Converter.main(Unknown Source)
<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/b/be/WP5304_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 129477)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
