Macrophage-stimulating protein (MSP) signaling (Homo sapiens)
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A network map of Macrophage-stimulating protein (MSP) signaling
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- Thobe MN, Gurusamy D, Pathrose P, Waltz SE; ''The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells.''; Oncogene, 2010 PubMed Europe PMC Scholia
- Wei X, Hao L, Ni S, Liu Q, Xu J, Correll PH; ''Altered exon usage in the juxtamembrane domain of mouse and human RON regulates receptor activity and signaling specificity.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
- Santoro MM, Gaudino G, Villa-Moruzzi E; ''Protein phosphatase 1 binds to phospho-Ser-1394 of the macrophage-stimulating protein receptor.''; Biochem J, 2003 PubMed Europe PMC Scholia
- Moxley KM, Wang L, Welm AL, Bieniasz M; ''Short-form Ron is a novel determinant of ovarian cancer initiation and progression.''; Genes Cancer, 2016 PubMed Europe PMC Scholia
- Yu Q, Wang J, Li T, Xu X, Guo X, Ding S, Zhu L, Zou G, Chen Y, Zhang X; ''RON Mediates Tumor-Promoting Effects in Endometrial Adenocarcinoma.''; Biomed Res Int, 2021 PubMed Europe PMC Scholia
- Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, Huang M, Liu R, Lin Y, Tan C, Xu M, Zhang Z; ''Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer.''; Cell Biol Toxicol, 2021 PubMed Europe PMC Scholia
- Zhang J, Sun L, Li W, Wang Y, Li X, Liu Y; ''Overexpression of macrophage stimulating 1 enhances the anti-tumor effects of IL-24 in esophageal cancer via inhibiting ERK-Mfn2 signaling-dependent mitophagy.''; Biomed Pharmacother, 2019 PubMed Europe PMC Scholia
- Danilkovitch A, Skeel A, Leonard EJ; ''Macrophage stimulating protein-induced epithelial cell adhesion is mediated by a PI3-K-dependent, but FAK-independent mechanism.''; Exp Cell Res, 1999 PubMed Europe PMC Scholia
- Privette Vinnedge LM, Benight NM, Wagh PK, Pease NA, Nashu MA, Serrano-Lopez J, Adams AK, Cancelas JA, Waltz SE, Wells SI; ''The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers.''; Oncogene, 2015 PubMed Europe PMC Scholia
- Chanda D, Li T, Song KH, Kim YH, Sim J, Lee CH, Chiang JY, Choi HS; ''Hepatocyte growth factor family negatively regulates hepatic gluconeogenesis via induction of orphan nuclear receptor small heterodimer partner in primary hepatocytes.''; J Biol Chem, 2009 PubMed Europe PMC Scholia
- Baird AM, Easty D, Jarzabek M, Shiels L, Soltermann A, Klebe S, Raeppel S, MacDonagh L, Wu C, Griggs K, Kirschner MB, Stanfill B, Nonaka D, Goparaju CM, Murer B, Fennell DA, O'Donnell DM, Barr MP, Mutti L, Reid G, Finn S, Cuffe S, Pass HI, Opitz I, Byrne AT, O'Byrne KJ, Gray SG; ''When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?''; Front Endocrinol (Lausanne), 2019 PubMed Europe PMC Scholia
- Lu T, Wang Z, Prativa S, Xu Y, Wang T, Zhang Y, Yu L, Xu N, Tang J, You W, Chen G, Zhang JH; ''Macrophage stimulating protein preserves blood brain barrier integrity after intracerebral hemorrhage through recepteur d'origine nantais dependent GAB1/Src/β-catenin pathway activation in a mouse model.''; J Neurochem, 2019 PubMed Europe PMC Scholia
- Côté M, Miller AD, Liu SL; ''Human RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence.''; Biochem Biophys Res Commun, 2007 PubMed Europe PMC Scholia
- Chanda D, Li J, Oligschlaeger Y, Jeurissen ML, Houben T, Walenbergh SM, Shiri-Sverdlov R, Neumann D; ''MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.''; Exp Mol Med, 2016 PubMed Europe PMC Scholia
- Kauder SE, Santell L, Mai E, Wright LY, Luis E, N'Diaye EN, Lutman J, Ratti N, Sa SM, Maun HR, Stefanich E, Gonzalez LC, Graham RR, Diehl L, Faubion WA Jr, Keir ME, Young J, Chaudhuri A, Lazarus RA, Egen JG; ''Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.''; PLoS One, 2013 PubMed Europe PMC Scholia
- Iwama A, Yamaguchi N, Suda T; ''STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family.''; EMBO J, 1996 PubMed Europe PMC Scholia
- Zhao H, Chen MS, Lo YH, Waltz SE, Wang J, Ho PC, Vasiliauskas J, Plattner R, Wang YL, Wang SC; ''The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer.''; Oncogene, 2014 PubMed Europe PMC Scholia
- Ma Q, Guin S, Padhye SS, Zhou YQ, Zhang RW, Wang MH; ''Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein.''; Mol Cancer, 2011 PubMed Europe PMC Scholia
- Danilkovitch A, Donley S, Skeel A, Leonard EJ; ''Two independent signaling pathways mediate the antiapoptotic action of macrophage-stimulating protein on epithelial cells.''; Mol Cell Biol, 2000 PubMed Europe PMC Scholia
- Wilson CB, Ray M, Lutz M, Sharda D, Xu J, Hankey PA; ''The RON receptor tyrosine kinase regulates IFN-gamma production and responses in innate immunity.''; J Immunol, 2008 PubMed Europe PMC Scholia
- Gunella G, Bardelli C, Amoruso A, Viano I, Balbo P, Brunelleschi S; ''Macrophage-stimulating protein differently affects human alveolar macrophages from smoker and non-smoker patients: evaluation of respiratory burst, cytokine release andNF-kappaB pathway.''; Br J Pharmacol, 2006 PubMed Europe PMC Scholia
- Jeong BC, Oh SH, Lee MN, Koh JT; ''Macrophage-Stimulating Protein Enhances Osteoblastic Differentiation via the Recepteur d'Origine Nantais Receptor and Extracellular Signal-Regulated Kinase Signaling Pathway.''; J Bone Metab, 2020 PubMed Europe PMC Scholia
- Park JS, Choi HI, Kim DH, Kim CS, Bae EH, Ma SK, Kim SW; ''RON Receptor Tyrosine Kinase Regulates Epithelial Mesenchymal Transition and the Expression of Pro-Fibrotic Markers via Src/Smad Signaling in HK-2 and NRK49F Cells.''; Int J Mol Sci, 2019 PubMed Europe PMC Scholia
- Chaudhuri A, Wilson NS, Yang B, Paler Martinez A, Liu J, Zhu C, Bricker N, Couto S, Modrusan Z, French D, Cupp J, Ashkenazi A; ''Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages.''; Immunol Cell Biol, 2013 PubMed Europe PMC Scholia
- Ling Y, Kuang Y, Chen LL, Lao WF, Zhu YR, Wang LQ, Wang D; ''A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells.''; Oncotarget, 2017 PubMed Europe PMC Scholia
- Tsutsui S, Noorbakhsh F, Sullivan A, Henderson AJ, Warren K, Toney-Earley K, Waltz SE, Power C; ''RON-regulated innate immunity is protective in an animal model of multiple sclerosis.''; Ann Neurol, 2005 PubMed Europe PMC Scholia
- Faham N, Zhao L, Welm AL; ''mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential.''; NPJ Breast Cancer, 2018 PubMed Europe PMC Scholia
- Zhang K, Yao HP, Wang MH; ''Activation of RON differentially regulates claudin expression and localization: role of claudin-1 in RON-mediated epithelial cell motility.''; Carcinogenesis, 2008 PubMed Europe PMC Scholia
- Cunha S, Lin YC, Goossen EA, DeVette CI, Albertella MR, Thomson S, Mulvihill MJ, Welm AL; ''The RON receptor tyrosine kinase promotes metastasis by triggering MBD4-dependent DNA methylation reprogramming.''; Cell Rep, 2014 PubMed Europe PMC Scholia
- Ganesan R, Kolumam GA, Lin SJ, Xie MH, Santell L, Wu TD, Lazarus RA, Chaudhuri A, Kirchhofer D; ''Proteolytic activation of pro-macrophage-stimulating protein by hepsin.''; Mol Cancer Res, 2011 PubMed Europe PMC Scholia
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