Cancer pathways (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. ''Pathways in cancer''; https://www.genome.jp/pathway/map05200,

History

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Compare	Revision	Action	Time	User	Comment
	129459	view	01:04, 23 April 2024	Eweitz	Modified title
	129136	view	16:45, 12 March 2024	Khanspers	minor tweak to test
	128705	view	22:04, 20 February 2024	Egonw	Made a few pathways clickable
	128257	view	00:14, 30 January 2024	Khanspers	Modified description
	128256	view	00:11, 30 January 2024	Khanspers	updated lit ref
	128254	view	00:08, 30 January 2024	Khanspers	Ontology Term : 'cancer' added !
	128253	view	00:08, 30 January 2024	Khanspers	Ontology Term : 'altered signaling pathway' added !
	128252	view	00:06, 30 January 2024	Khanspers	added cell shape, legend, phospho sites
	127898	view	00:17, 10 January 2024	Khanspers	node sizing and layout
	127897	view	00:08, 10 January 2024	Khanspers	added cytokines and cytokine receptors
	127896	view	22:57, 9 January 2024	Khanspers	layout
	127895	view	22:51, 9 January 2024	Khanspers	added wnts
	127872	view	22:50, 3 January 2024	Khanspers	layout
	127871	view	19:59, 3 January 2024	Khanspers	complexes and interactions
	127866	view	23:51, 2 January 2024	Khanspers	interactions
	127865	view	23:38, 2 January 2024	Khanspers	updated interactions etc
	127864	view	22:58, 2 January 2024	Khanspers	layout and interactions
	127863	view	22:51, 2 January 2024	Khanspers	added gst
	127861	view	22:41, 2 January 2024	Khanspers	added ecm
	127859	view	22:33, 2 January 2024	Khanspers	added wnt, fzd
	127827	view	21:26, 21 December 2023	Khanspers	Ontology Term : 'cancer pathway' added !
	127826	view	21:25, 21 December 2023	Khanspers	Modified title
	127825	view	21:24, 21 December 2023	Khanspers	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
4-HNE	Metabolite	C21642 (KEGG Compound)
ABL1	GeneProduct	ABL1 (HGNC)
ADCY1	GeneProduct	ADCY1 (HGNC)
ADCY2	GeneProduct	ADCY2 (HGNC)
ADCY3	GeneProduct	ADCY3 (HGNC)
ADCY4	GeneProduct	ADCY4 (HGNC)
ADCY5	GeneProduct	ADCY5 (HGNC)
ADCY6	GeneProduct	ADCY6 (HGNC)
ADCY7	GeneProduct	ADCY7 (HGNC)
ADCY8	GeneProduct	ADCY8 (HGNC)
ADCY9	GeneProduct	ADCY9 (HGNC)
AGT	GeneProduct	AGT (HGNC)
AGTR1	GeneProduct	AGTR1 (HGNC)
AKT1	GeneProduct	AKT1 (HGNC)
AKT2	GeneProduct	AKT2 (HGNC)
AKT3	GeneProduct	AKT3 (HGNC)
ALK	GeneProduct	ALK (HGNC)
APAF1	GeneProduct	APAF1 (HGNC)
APC2	GeneProduct	APC2 (HGNC)
APC	GeneProduct	APC (HGNC)
APPL1	GeneProduct	APPL1 (HGNC)
ARAF	GeneProduct	ARAF (HGNC)
AR	GeneProduct	AR (HGNC)
ARHGEF11	GeneProduct	ARHGEF11 (HGNC)
ARHGEF12	GeneProduct	ARHGEF12 (HGNC)
ARHGEF1	GeneProduct	ARHGEF1 (HGNC)
ARNT2	GeneProduct	ARNT2 (HGNC)
ARNT	GeneProduct	ARNT (HGNC)
AXIN1	GeneProduct	AXIN1 (HGNC)
AXIN2	GeneProduct	AXIN2 (HGNC)
Acrolein	Metabolite	C01471 (KEGG Compound)
Adherens junction	Pathway
Androstenedione	Metabolite	HMDB00053 (HMDB)
Apoptosis	Pathway	WP254 (WikiPathways)
BAD	GeneProduct	BAD (HGNC)
BAK1	GeneProduct	BAK1 (HGNC)
BAX	GeneProduct	BAX (HGNC)
BBC3	GeneProduct	BBC3 (HGNC)
BCL2	GeneProduct	BCL2 (HGNC)
BCL2L11	GeneProduct	BCL2L11 (HGNC)
BCL2L1	GeneProduct	BCL2L1 (HGNC)
BCR	GeneProduct	BCR (HGNC)
BDKRB1	GeneProduct	BDKRB1 (HGNC)
BDKRB2	GeneProduct	BDKRB2 (HGNC)
BID	GeneProduct	BID (HGNC)
BIRC2	GeneProduct	BIRC2 (HGNC)
BIRC3	GeneProduct	BIRC3 (HGNC)
BIRC5	GeneProduct	BIRC5 (HGNC)
BIRC7	GeneProduct	BIRC7 (HGNC)
BMP2	GeneProduct	BMP2 (HGNC)
BMP4	GeneProduct	BMP4 (HGNC)
BRAF	GeneProduct	BRAF (HGNC)
BRCA2	GeneProduct	BRCA2 (HGNC)
CALML1	GeneProduct	CALML1 (HGNC)
CALML2	GeneProduct	CALML2 (HGNC)
CALML3	GeneProduct	CALML3 (HGNC)
CALML4	GeneProduct	CALML4 (HGNC)
CALML5	GeneProduct	CALML5 (HGNC)
CALML6	GeneProduct	CALML6 (HGNC)
CAMK2A	GeneProduct	CAMK2A (HGNC)
CAMK2B	GeneProduct	CAMK2B (HGNC)
CAMK2D	GeneProduct	CAMK2D (HGNC)
CAMK2G	GeneProduct	CAMK2G (HGNC)
CASP3	GeneProduct	CASP3 (HGNC)
CASP7	GeneProduct	CASP7 (HGNC)
CASP8	GeneProduct	CASP8 (HGNC)
CASP9	GeneProduct	CASP9 (HGNC)
CBL	GeneProduct	CBL (HGNC)
CCDC42	GeneProduct	CCDC42 (HGNC)
CCDC6	GeneProduct	CCDC6 (HGNC)
CCNA1	GeneProduct	CCNA1 (HGNC)
CCNA2	GeneProduct	CCNA2 (HGNC)
CCND1	GeneProduct	CCND1 (HGNC)
CCND2	GeneProduct	CCND2 (HGNC)
CCND3	GeneProduct	CCND3 (HGNC)
CCNE1	GeneProduct	CCNE1 (HGNC)
CCNE2	GeneProduct	CCNE2 (HGNC)
CDH1	GeneProduct	CDH1 (HGNC)
CDK2	GeneProduct	CDK2 (HGNC)
CDK4	GeneProduct	CDK4 (HGNC)
CDK6	GeneProduct	CDK6 (HGNC)
CDKN1A	GeneProduct	CDKN1A (HGNC)
CDKN1B	GeneProduct	CDKN1B (HGNC)
CDKN2A	GeneProduct	CDKN2A (HGNC)
CDKN2B	GeneProduct	CDKN2B (HGNC)
CEBPA	GeneProduct	CEBPA (HGNC)
CHUK	GeneProduct	CHUK (HGNC)
CKS1B	GeneProduct	CKS1B (HGNC)
COL4A1	GeneProduct	COL4A1 (HGNC)
COL4A2	GeneProduct	COL4A2 (HGNC)
COL4A3	GeneProduct	COL4A3 (HGNC)
COL4A4	GeneProduct	COL4A4 (HGNC)
COL4A5	GeneProduct	COL4A5 (HGNC)
COL4A6	GeneProduct	COL4A6 (HGNC)
CREBBP	GeneProduct	CREBBP (HGNC)
CRK	GeneProduct	CRK (HGNC)
CRKL	GeneProduct	CRKL (HGNC)
CSF1R	GeneProduct	CSF1R (HGNC)
CSF2RA	GeneProduct	CSF2RA (HGNC)
CSF3R	GeneProduct	CSF3R (HGNC)
CTBP1	GeneProduct	CTBP1 (HGNC)
CTBP2	GeneProduct	CTBP2 (HGNC)
CTNNA1	GeneProduct	CTNNA1 (HGNC)
CTNNA2	GeneProduct	CTNNA2 (HGNC)
CTNNA3	GeneProduct	CTNNA3 (HGNC)
CTNNB1	GeneProduct	CTNNB1 (HGNC)
CUL1	GeneProduct	CUL1 (HGNC)
CUL2	GeneProduct	CUL2 (HGNC)
CXCL12	GeneProduct	CXCL12 (HGNC)
CXCL8	GeneProduct	CXCL8 (HGNC)
CXCR4	GeneProduct	CXCR4 (HGNC)
CYCS	GeneProduct	CYCS (HGNC)
Ca2+	Metabolite	CHEBI:29108 (ChEBI)
Calcium signaling pathway	Pathway
Cell cycle	Pathway	WP179 (WikiPathways)
Cholesterol	Metabolite	HMDB00067 (HMDB)
Cortisol	Metabolite	HMDB00063 (HMDB)
Cortisone	Metabolite	HMDB02802 (HMDB)
DAG	Metabolite	C00165 (KEGG Compound)
DAPK1	GeneProduct	DAPK1 (HGNC)
DAPK2	GeneProduct	DAPK2 (HGNC)
DAPK3	GeneProduct	DAPK3 (HGNC)
DCC	GeneProduct	DCC (HGNC)
DDB2	GeneProduct	DDB2 (HGNC)
DLL1	GeneProduct	DLL1 (HGNC)
DLL3	GeneProduct	DLL3 (HGNC)
DLL4	GeneProduct	DLL4 (HGNC)
DNA	Metabolite	CHEBI:16991 (ChEBI)
DVL1	GeneProduct	DVL1 (HGNC)
DVL2	GeneProduct	DVL2 (HGNC)
DVL3	GeneProduct	DVL3 (HGNC)
Dehydroepiandrosterone	Metabolite	HMDB00077 (HMDB)
Dihydrotestosterone	Metabolite	HMDB02961 (HMDB)
E2F1	GeneProduct	E2F1 (HGNC)
E2F2	GeneProduct	E2F2 (HGNC)
E2F3	GeneProduct	E2F3 (HGNC)
EDN1	GeneProduct	EDN1 (HGNC)
EDNRA	GeneProduct	EDNRA (HGNC)
EDNRB	GeneProduct	EDNRB (HGNC)
EGF	GeneProduct	EGF (HGNC)
EGFR	GeneProduct	EGFR (HGNC)
EGLN1	GeneProduct	EGLN1 (HGNC)
EGLN2	GeneProduct	EGLN2 (HGNC)
EGLN3	GeneProduct	EGLN3 (HGNC)
ELK1	GeneProduct	ELK1 (HGNC)
ELOB	GeneProduct	ELOB (HGNC)
ELOC	GeneProduct	ELOC (HGNC)
EML4	GeneProduct	EML4 (HGNC)
EP300	GeneProduct	EP300 (HGNC)
EPAS1	GeneProduct	EPAS1 (HGNC)
ERBB2	GeneProduct	ERBB2 (HGNC)
ESR1	GeneProduct	ESR1 (HGNC)
ESR2	GeneProduct	ESR2 (HGNC)
ETS1	GeneProduct	ETS1 (HGNC)
Estradiol	Metabolite	HMDB00151 (HMDB)
Estrogen signaling pathway	Pathway	WP712 (WikiPathways)
F2	GeneProduct	F2 (HGNC)
F2R	GeneProduct	F2R (HGNC)
F2RL3	GeneProduct	F2RL3 (HGNC)
FADD	GeneProduct	FADD (HGNC)
FAS	GeneProduct	FAS (HGNC)
FASLG	GeneProduct	FASLG (HGNC)
FGF1	GeneProduct	FGF1 (HGNC)
FGFR1	GeneProduct	FGFR1 (HGNC)
FGFR2	GeneProduct	FGFR2 (HGNC)
FGFR3	GeneProduct	FGFR3 (HGNC)
FGFR4	GeneProduct	FGFR4 (HGNC)
FH	GeneProduct	FH (HGNC)
FLT3	GeneProduct	FLT3 (HGNC)
FLT3LG	GeneProduct	FLT3LG (HGNC)
FLT4	GeneProduct	FLT4 (HGNC)
FN1	GeneProduct	FN1 (HGNC)
FOS	GeneProduct	FOS (HGNC)
FOXO1	GeneProduct	FOXO1 (HGNC)
FRAT1	GeneProduct	FRAT1 (HGNC)
FRAT2	GeneProduct	FRAT2 (HGNC)
FZD10	GeneProduct	FZD10 (HGNC)
FZD1	GeneProduct	FZD1 (HGNC)
FZD2	GeneProduct	FZD2 (HGNC)
FZD3	GeneProduct	FZD3 (HGNC)
FZD4	GeneProduct	FZD4 (HGNC)
FZD5	GeneProduct	FZD5 (HGNC)
FZD6	GeneProduct	FZD6 (HGNC)
FZD7	GeneProduct	FZD7 (HGNC)
FZD8	GeneProduct	FZD8 (HGNC)
FZD9	GeneProduct	FZD9 (HGNC)
Flutamide	Metabolite	HMDB14642 (HMDB)
Focal adhesion	Pathway	WP306 (WikiPathways)
GADD45A	GeneProduct	GADD45A (HGNC)
GADD45B	GeneProduct	GADD45B (HGNC)
GADD45G	GeneProduct	GADD45G (HGNC)
GLI1	GeneProduct	GLI1 (HGNC)
GLI2	GeneProduct	GLI2 (HGNC)
GLI3	GeneProduct	GLI3 (HGNC)
GNA11	GeneProduct	GNA11 (HGNC)
GNA12	GeneProduct	GNA12 (HGNC)
GNA13	GeneProduct	GNA13 (HGNC)
GNAI1	GeneProduct	GNAI1 (HGNC)
GNAI2	GeneProduct	GNAI2 (HGNC)
GNAI3	GeneProduct	GNAI3 (HGNC)
GNAQ	GeneProduct	GNAQ (HGNC)
GNAS	GeneProduct	GNAS (HGNC)
GNB1	GeneProduct	GNB1 (HGNC)
GNB2	GeneProduct	GNB2 (HGNC)
GNB3	GeneProduct	GNB3 (HGNC)
GNB4	GeneProduct	GNB4 (HGNC)
GNB5	GeneProduct	GNB5 (HGNC)
GNG10	GeneProduct	GNG10 (HGNC)
GNG11	GeneProduct	GNG11 (HGNC)
GNG12	GeneProduct	GNG12 (HGNC)
GNG13	GeneProduct	GNG13 (HGNC)
GNG2	GeneProduct	GNG2 (HGNC)
GNG3	GeneProduct	GNG3 (HGNC)
GNG4	GeneProduct	GNG4 (HGNC)
GNG5	GeneProduct	ENSG00000174021 (Ensembl)
GNG7	GeneProduct	GNG7 (HGNC)
GNG8	GeneProduct	GNG8 (HGNC)
GNGT1	GeneProduct	GNGT1 (HGNC)
GNGT2	GeneProduct	GNGT2 (HGNC)
GRB2	GeneProduct	GRB2 (HGNC)
GSK3B	GeneProduct	GSK3B (HGNC)
GSTA1	GeneProduct	GSTA1 (HGNC)
GSTA2	GeneProduct	GSTA2 (HGNC)
GSTA3	GeneProduct	GSTA3 (HGNC)
GSTA4	GeneProduct	GSTA4 (HGNC)
GSTA5	GeneProduct	GSTA5 (HGNC)
GSTM1	GeneProduct	GSTM1 (HGNC)
GSTM2	GeneProduct	GSTM2 (HGNC)
GSTM3	GeneProduct	GSTM3 (HGNC)
GSTM4	GeneProduct	GSTM4 (HGNC)
GSTM5	GeneProduct	GSTM5 (HGNC)
GSTO1	GeneProduct	GSTO1 (HGNC)
GSTO2	GeneProduct	GSTO2 (HGNC)
GSTP1	GeneProduct	GSTP1 (HGNC)
GSTT1	GeneProduct	GSTT1 (HGNC)
GSTT2B	GeneProduct	GSTT2B (HGNC)
GSTT2	GeneProduct	GSTT2 (HGNC)
HDAC1	GeneProduct	HDAC1 (HGNC)
HDAC2	GeneProduct	HDAC2 (HGNC)
HES1	GeneProduct	HES1 (HGNC)
HES5	GeneProduct	HES5 (HGNC)
HEY1	GeneProduct	HEY1 (HGNC)
HEY2	GeneProduct	HEY2 (HGNC)
HEYL	GeneProduct	HEYL (HGNC)
HGF	GeneProduct	HGF (HGNC)
HHIP	GeneProduct	HHIP (HGNC)
HIF-1 signaling pathway	Pathway
HIF1A	GeneProduct	HIF1A (HGNC)
HMOX1	GeneProduct	HMOX1 (HGNC)
HRAS	GeneProduct	HRAS (HGNC)
HSP90AA1	GeneProduct	HSP90AA1 (HGNC)
HSP90AB1	GeneProduct	HSP90AB1 (HGNC)
HSP90B1	GeneProduct	HSP90B1 (HGNC)
Hedgehog signaling pathway	Pathway	WP4249 (WikiPathways)
Hydrogen peroxide	Metabolite	HMDB03125 (HMDB)
Hydroperoxyl radical	Metabolite	C21641 (ChEMBL compound)
Hydroxyl radical	Metabolite	C16844 (KEGG Compound)
IGF1	GeneProduct	IGF1 (HGNC)
IGF1R	GeneProduct	IGF1R (HGNC)
IGF2	GeneProduct	IGF2 (HGNC)
IKBKB	GeneProduct	IKBKB (HGNC)
IKBKG	GeneProduct	IKBKG (HGNC)
IL6	GeneProduct	IL6 (HGNC)
IP3	Metabolite	C01245 (KEGG Compound)
ITGA2B	GeneProduct	ITGA2B (HGNC)
ITGA2	GeneProduct	ITGA2 (HGNC)
ITGA3	GeneProduct	ITGA3 (HGNC)
ITGA6	GeneProduct	ITGA6 (HGNC)
ITGAV	GeneProduct	ITGAV (HGNC)
ITGB1	GeneProduct	ITGB1 (HGNC)
JAG1	GeneProduct	JAG1 (HGNC)
JAG2	GeneProduct	JAG2 (HGNC)
JAK1	GeneProduct	JAK1 (HGNC)
JAK2	GeneProduct	JAK2 (HGNC)
JAK3	GeneProduct	JAK3 (HGNC)
JUN	GeneProduct	JUN (HGNC)
JUP	GeneProduct	JUP (HGNC)
Jak-STAT signaling pathway	Pathway
KEAP1	GeneProduct	KEAP1 (HGNC)
KIF7	GeneProduct	KIF7 (HGNC)
KIT	GeneProduct	KIT (HGNC)
KITLG	GeneProduct	KITLG (HGNC)
KLK3	GeneProduct	KLK3 (HGNC)
KNG1	GeneProduct	KNG1 (HGNC)
KRAS	GeneProduct	KRAS (HGNC)
LAMA1	GeneProduct	LAMA1 (HGNC)
LAMA2	GeneProduct	LAMA2 (HGNC)
LAMA3	GeneProduct	LAMA3 (HGNC)
LAMA4	GeneProduct	LAMA4 (HGNC)
LAMA5	GeneProduct	LAMA5 (HGNC)
LAMB1	GeneProduct	LAMB1 (HGNC)
LAMB2	GeneProduct	LAMB2 (HGNC)
LAMB3	GeneProduct	LAMB3 (HGNC)
LAMB4	GeneProduct	LAMB4 (HGNC)
LAMC1	GeneProduct	LAMC1 (HGNC)
LAMC2	GeneProduct	LAMC2 (HGNC)
LAMC3	GeneProduct	LAMC3 (HGNC)
LEF1	GeneProduct	LEF1 (HGNC)
LPAR1	GeneProduct	LPAR1 (HGNC)
LPAR2	GeneProduct	LPAR2 (HGNC)
LPAR3	GeneProduct	LPAR3 (HGNC)
LPAR4	GeneProduct	LPAR4 (HGNC)
LPAR5	GeneProduct	LPAR5 (HGNC)
LPAR6	GeneProduct	LPAR6 (HGNC)
LRP5	GeneProduct	LRP5 (HGNC)
LRP6	GeneProduct	LRP6 (HGNC)
MAP2K1	GeneProduct	MAP2K1 (HGNC)
MAP2K2	GeneProduct	MAP2K2 (HGNC)
MAPK signaling pathway	Pathway	WP382 (WikiPathways)
MAPK10	GeneProduct	MAPK10 (HGNC)
MAPK1	GeneProduct	MAPK1 (HGNC)
MAPK3	GeneProduct	MAPK3 (HGNC)
MAPK8	GeneProduct	MAPK8 (HGNC)
MAPK9	GeneProduct	MAPK9 (HGNC)
MAX	GeneProduct	MAX (HGNC)
MDM2	GeneProduct	MDM2 (HGNC)
MECOM	GeneProduct	MECOM (HGNC)
MET	GeneProduct	MET (HGNC)
MGST1	GeneProduct	MGST1 (HGNC)
MGST2	GeneProduct	MGST2 (HGNC)
MGST3	GeneProduct	MGST3 (HGNC)
MITF	GeneProduct	MITF (HGNC)
MLH1	GeneProduct	MLH1 (HGNC)
MMP1	GeneProduct	MMP1 (HGNC)
MMP2	GeneProduct	MMP2 (HGNC)
MMP3	GeneProduct	MMP3 (HGNC)
MSH2	GeneProduct	MSH2 (HGNC)
MSH3	GeneProduct	MSH3 (HGNC)
MSH6	GeneProduct	MSH6 (HGNC)
MST1	GeneProduct	MST1 (HGNC)
MTOR	GeneProduct	MTOR (HGNC)
MYC	GeneProduct	MYC (HGNC)
Malate	Metabolite	CHEBI:30797 (ChEBI)
NCOA1	GeneProduct	NCOA1 (HGNC)
NCOA3	GeneProduct	NCOA3 (HGNC)
NCOA4	GeneProduct	NCOA4 (HGNC)
NFE2L2	GeneProduct	NFE2L2 (HGNC)
NFKB1	GeneProduct	NFKB1 (HGNC)
NFKB2	GeneProduct	NFKB2 (HGNC)
NFKBIA	GeneProduct	NFKBIA (HGNC)
NKX3-1	GeneProduct	NKX3-1 (HGNC)
NOS2	GeneProduct	NOS2 (HGNC)
NOTCH1	GeneProduct	NOTCH1 (HGNC)
NOTCH2	GeneProduct	NOTCH2 (HGNC)
NOTCH3	GeneProduct	NOTCH3 (HGNC)
NOTCH4	GeneProduct	NOTCH4 (HGNC)
NQO1	GeneProduct	NQO1 (HGNC)
NRAS	GeneProduct	NRAS (HGNC)
NTRK1	GeneProduct	NTRK1 (HGNC)
Nitric oxide	Metabolite	HMDB03378 (HMDB)
Notch signaling pathway	Pathway	WP268 (WikiPathways)
PA	Metabolite	C00416 (KEGG Compound)
PAX8	GeneProduct	PAX8 (HGNC)
PDGFA	GeneProduct	PDGFA (HGNC)
PDGFB	GeneProduct	PDGFB (HGNC)
PDGFRA	GeneProduct	PDGFRA (HGNC)
PDGFRB	GeneProduct	PDGFRB (HGNC)
PGE2	Metabolite	HMDB01220 (HMDB)
PGF	GeneProduct	PGF (HGNC)
PI3K-Akt signaling pathway	Pathway	WP4172 (KEGG Pathway)
PIK3CA	GeneProduct	PIK3CA (HGNC)
PIK3CB	GeneProduct	PIK3CB (HGNC)
PIK3CD	GeneProduct	PIK3CD (HGNC)
PIK3R1	GeneProduct	PIK3R1 (HGNC)
PIK3R2	GeneProduct	PIK3R2 (HGNC)
PIK3R3	GeneProduct	PIK3R3 (HGNC)
PIM1	GeneProduct	PIM1 (HGNC)
PIM2	GeneProduct	PIM2 (HGNC)
PIP3	Metabolite	C05981 (KEGG Compound)
PLCB1	GeneProduct	PLCB1 (HGNC)
PLCB2	GeneProduct	PLCB2 (HGNC)
PLCB3	GeneProduct	PLCB3 (HGNC)
PLCB4	GeneProduct	PLCB4 (HGNC)
PLCG1	GeneProduct	PLCG1 (HGNC)
PLCG2	GeneProduct	PLCG2 (HGNC)
PLD1	GeneProduct	PLD1 (HGNC)
PLD2	GeneProduct	PLD2 (HGNC)
PLEKHG5	GeneProduct	PLEKHG5 (HGNC)
PMAIP1	GeneProduct	PMAIP1 (HGNC)
PML	GeneProduct	PML (HGNC)
POLK	GeneProduct	POLK (HGNC)
PPAR signaling pathway	Pathway	WP3942 (WikiPathways)
PPARD	GeneProduct	PPARD (HGNC)
PPARG	GeneProduct	PPARG (HGNC)
PRKACA	GeneProduct	PRKACA (HGNC)
PRKACB	GeneProduct	PRKACB (HGNC)
PRKACG	GeneProduct	PRKACG (HGNC)
PRKCA	GeneProduct	PRKCA (HGNC)
PRKCB	GeneProduct	PRKCB (HGNC)
PRKCG	GeneProduct	PRKCG (HGNC)
PTCH1	GeneProduct	PTCH1 (HGNC)
PTCH2	GeneProduct	PTCH2 (HGNC)
PTEN	GeneProduct	PTEN (HGNC)
PTGER1	GeneProduct	PTGER1 (HGNC)
PTGER2	GeneProduct	PTGER2 (HGNC)
PTGER3	GeneProduct	PTGER3 (HGNC)
PTGER4	GeneProduct	PTGER4 (HGNC)
PTGS2	GeneProduct	PTGS2 (HGNC)
PTK2	GeneProduct	PTK2 (HGNC)
Progesterone	Metabolite	HMDB01830 (HMDB)
RAC1	GeneProduct	RAC1 (HGNC)
RAC2	GeneProduct	5880 (Entrez Gene)
RAC3	GeneProduct	RAC3 (HGNC)
RAD51	GeneProduct	RAD51 (HGNC)
RAF1	GeneProduct	RAF1 (HGNC)
RALA	GeneProduct	RALA (HGNC)
RALBP1	GeneProduct	RALBP1 (HGNC)
RALB	GeneProduct	RALB (HGNC)
RALGDS	GeneProduct	RALGDS (HGNC)
RARA	GeneProduct	RARA (HGNC)
RARB	GeneProduct	RARB (HGNC)
RASGRP1	GeneProduct	RASGRP1 (HGNC)
RASGRP2	GeneProduct	RASGRP2 (HGNC)
RASGRP3	GeneProduct	RASGRP3 (HGNC)
RASGRP4	GeneProduct	RASGRP4 (HGNC)
RASSF1	GeneProduct	RASSF1 (HGNC)
RASSF5	GeneProduct	RASSF5 (HGNC)
RB1	GeneProduct	RB1 (HGNC)
RBX1	GeneProduct	RBX1 (HGNC)
RELA	GeneProduct	RELA (HGNC)
RET	GeneProduct	RET (HGNC)
RHOA	GeneProduct	RHOA (HGNC)
ROCK1	GeneProduct	ROCK1 (HGNC)
ROCK2	GeneProduct	ROCK2 (HGNC)
RPS6KA5	GeneProduct	RPS6KA5 (HGNC)
RPS6KB1	GeneProduct	RPS6KB1 (HGNC)
RPS6KB2	GeneProduct	RPS6KB2 (HGNC)
RUNX1	GeneProduct	RUNX1 (HGNC)
RUNX1T1	GeneProduct	RUNX1T1 (HGNC)
RXRA	GeneProduct	RXRA (HGNC)
RXRB	GeneProduct	RXRB (HGNC)
RXRG	GeneProduct	RXRG (HGNC)
Retinoic Acid	Metabolite	CHEBI:15367 (ChEBI)
SHH	GeneProduct	SHH (HGNC)
SKP1	GeneProduct	SKP1 (HGNC)
SKP2	GeneProduct	SKP2 (HGNC)
SLC2A1	GeneProduct	SLC2A1 (HGNC)
SMAD2	GeneProduct	SMAD2 (HGNC)
SMAD3	GeneProduct	SMAD3 (HGNC)
SMAD4	GeneProduct	SMAD4 (HGNC)
SMO	GeneProduct	SMO (HGNC)
SOS1	GeneProduct	SOS1 (HGNC)
SOS2	GeneProduct	SOS2 (HGNC)
SP1	GeneProduct	ENSG00000185591 (Ensembl)
SPI1	GeneProduct	SPI1 (HGNC)
STAT1	GeneProduct	STAT1 (HGNC)
STAT2	GeneProduct	STAT2 (HGNC)
STAT3	GeneProduct	STAT3 (HGNC)
STAT4	GeneProduct	STAT4 (HGNC)
STAT5A	GeneProduct	STAT5A (HGNC)
STAT5B	GeneProduct	STAT5B (HGNC)
STAT6	GeneProduct	STAT6 (HGNC)
SUFU	GeneProduct	SUFU (HGNC)
Superoxide	Metabolite	HMDB02168 (HMDB)
TCF7L1	GeneProduct	TCF7L1 (HGNC)
TCF7L2	GeneProduct	TCF7L2 (HGNC)
TCF7	GeneProduct	TCF7 (HGNC)
TERC	GeneProduct	TERC (HGNC)
TERT	GeneProduct	TERT (HGNC)
TFG	GeneProduct	TFG (HGNC)
TGF-beta signaling pathway	Pathway	WP560 (WikiPathways)
TGFA	GeneProduct	TGFA (HGNC)
TGFB1	GeneProduct	TGFB1 (HGNC)
TGFB2	GeneProduct	TGFB2 (HGNC)
TGFB3	GeneProduct	TGFB3 (HGNC)
TGFBR1	GeneProduct	TGFBR1 (HGNC)
TGFBR2	GeneProduct	TGFBR2 (HGNC)
TP53	GeneProduct	TP53 (HGNC)
TPM3	GeneProduct	TPM3 (HGNC)
TPR	GeneProduct	TPR (HGNC)
TRAF1	GeneProduct	TRAF1 (HGNC)
TRAF2	GeneProduct	TRAF2 (HGNC)
TRAF3	GeneProduct	TRAF3 (HGNC)
TRAF4	GeneProduct	TRAF4 (HGNC)
TRAF5	GeneProduct	TRAF5 (HGNC)
TRAF6	GeneProduct	TRAF6 (HGNC)
TXNRD1	GeneProduct	TXNRD1 (HGNC)
TXNRD2	GeneProduct	TXNRD2 (HGNC)
TXNRD3	GeneProduct	TXNRD3 (HGNC)
Testosterone	Metabolite	HMDB00234 (HMDB)
VEGF signaling pathway	Pathway	WP3888 (WikiPathways)
VEGFA	GeneProduct	VEGFA (HGNC)
VEGFB	GeneProduct	VEGFB (HGNC)
VEGFC	GeneProduct	VEGFC (HGNC)
VEGFD	GeneProduct	VEGFD (HGNC)
VHL	GeneProduct	VHL (HGNC)
WNT10A	GeneProduct	WNT10A (HGNC)
WNT10B	GeneProduct	WNT10B (HGNC)
WNT11	GeneProduct	WNT11 (HGNC)
WNT16	GeneProduct	WNT16 (HGNC)
WNT1	GeneProduct	WNT1 (HGNC)
WNT2B	GeneProduct	WNT2B (HGNC)
WNT2	GeneProduct	WNT2 (HGNC)
WNT3A	GeneProduct	WNT3A (HGNC)
WNT3	GeneProduct	WNT3 (HGNC)
WNT4	GeneProduct	WNT4 (HGNC)
WNT5A	GeneProduct	WNT5A (HGNC)
WNT5B	GeneProduct	WNT5B (HGNC)
WNT6	GeneProduct	WNT6 (HGNC)
WNT7A	GeneProduct	WNT7A (HGNC)
WNT7B	GeneProduct	WNT7B (HGNC)
WNT8A	GeneProduct	WNT8A (HGNC)
WNT8B	GeneProduct	WNT8B (HGNC)
WNT9A	GeneProduct	WNT9A (HGNC)
WNT9B	GeneProduct	WNT9B (HGNC)
Wnt signaling pathway	Pathway	WP428 (WikiPathways)
XIAP	GeneProduct	XIAP (HGNC)
ZBTB16	GeneProduct	ZBTB16 (HGNC)
ZBTB17	GeneProduct	ZBTB17 (HGNC)
cAMP signaling pathway	Pathway
cAMP	Metabolite	CHEBI:17489 (ChEBI)
fumarate	Metabolite	CHEBI:29806 (ChEBI)
mTOR signaling pathway	Pathway	WP3932 (WikiPathways)
p53 signaling pathway	Pathway

Annotated Interactions

No annotated interactions