Transcriptional activation by NRF2 (Bos taurus)

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1Phase II enzymesS-PCCAAT/XRET-PARES-PNucleusT-PMAFHMOX1NFE2L2PIK3CANQO1GSTA26-HITCC/EBP-betaAIMP2EPHB2GCLCPRKCAGCLMSulforaphaneMAPK8KEAP1NFE2L2Caffeic acid phenethyl esterCurcuminNFE2L2C/EBP-betaKEAP1


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP3(r29720) with a 83% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Surh YJ; ''Cancer chemoprevention with dietary phytochemicals.''; Nat Rev Cancer, 2003 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
105999view11:52, 16 August 2019MaintBotHMDB identifier normalization
80933view15:31, 30 June 2015Mkutmonhomology conversion
72383view15:30, 13 November 2013EgonwAdded a few metabolite identifiers.
72382view15:28, 13 November 2013EgonwFixed the PubChem-compound database name.
71409view19:01, 17 October 2013MaintBotAutomated update of data sources
63349view22:21, 9 May 2013MaintBotUpdated to 2013 gpml schema
40523view19:29, 1 March 2011MaintBotRemoved redundant pathway information and comments
33630view10:04, 1 December 2009MaintBotRemoved group label
30557view22:02, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
6-HITCMetaboliteFull name: 6-(Methylsulfinyl)hexylisothiocyanate, or Japanese horseradish wasabi
AIMP2GeneProduct520979 (Entrez Gene)
C/EBP-betaGeneProduct
Caffeic acid phenethyl esterMetabolite
CurcuminMetaboliteHMDB02269 (HMDB)
EPHB2GeneProduct535137 (Entrez Gene)
GCLCGeneProduct512468 (Entrez Gene)
GCLMGeneProduct525659 (Entrez Gene)
GSTA2GeneProduct
HMOX1GeneProduct513221 (Entrez Gene)
KEAP1GeneProduct532791 (Entrez Gene)
MAFGeneProduct782481 (Entrez Gene)
MAPK8GeneProduct539941 (Entrez Gene)
NFE2L2GeneProduct497024 (Entrez Gene)
NQO1GeneProduct519632 (Entrez Gene)
PIK3CAGeneProduct282306 (Entrez Gene)
PRKCAGeneProduct282001 (Entrez Gene)
SulforaphaneMetabolite5350 (PubChem)

Annotated Interactions

No annotated interactions